General Path: General concepts

Question 1

Pathology is the bridge between ___ and ____

Answer 1

basic sciences and clinical sciences

Question 2

_____ is used to describe the specific mechanism of how a disease develops

Answer 2

pathogenesis

Question 3

anatomic pathology involves what?

Answer 3

gross and histologic changes in tissues (necropsy, biopsy)

Question 4

clincial pahtology involves what?

Answer 4

the changes in the chemistry of fluids and the hematology, structure, and function of cells (cytology)

Question 5

clinical diagnosis is based on what?

Answer 5

data obtained from the case history, clinical signs, physical examination, and lab tests

Question 6

morphologic diagnosis is based on what?

Answer 6

predominant changes (lesions) in the tissues; macroscopic or microscopic

Question 7

morphologic diagnosis includes

Answer 7

severity, duration, distribution, nature of lesion

Question 8

what is the purpose of morphologic dx?

Answer 8

to relay info the the clinician to formulate a prognosis

Question 9

what are the special stains

Answer 9

giemsa stain
gomori methenamine silver (GMS)
gram stain

Question 10

immunohistochemistry

Answer 10

detection of ANTIGENS by specific antibodies linked to a chromagen

Question 11

IHC is commonly used to diagnose what?

Answer 11

neoplasia (infectious agents can also be targeted)

Question 12

subcellular structure of cells and microbes can be examined using

Answer 12

electronmicroscopy

Question 13

general pathology is the study of

Answer 13

basic responses of cells and tissues to injury

Question 14

systemic pathology is the study of

Answer 14

how each organ system reacts to injury associated with specific diseases