General Internal Medicine Flashcards

0
Q

What is mycophenolate mofetil?

A

immunosuppressant commonly used for transplant pts

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1
Q

What defines strong familial risk for colorectal cancer?

A

multiple first-degree relatives or 1 first-degree relative Dxed at or before age 60.

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2
Q

How should immunosuppressed pts be protected during an influenza epidemic?

A

oseltamivir and vaccination of close contacts

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3
Q

What strains of influenza is oseltamivir effective against?

A

A and B

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4
Q

What strains of influenza is rimantadine effective against?

A

neither - used to be effective against A, but now resistant

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5
Q

What kind of vaccine is the standard influenza vaccine given each fall?

A

inactivated

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6
Q

What is the normal JVP (in cm H2O)?

A

6-8 cm H2O

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7
Q

What do a systolic murmur, S3 heart sound, increased HR, and peripheral edema indicate in a pregnant woman?

A

normal findings

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8
Q

What are 2 potential causes of syncope in hypertrophic cardiomyopathy?

A

LV outflow obstruction, arrhythmia

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9
Q

What is neurocardiogenic syncope? Briefly describe the pathophysiology.

A

vasovagal episode; stimulus of tractus solitarius in brainstem leads to increased parasympathetic tone and decreased sympathetic tone –> hypotension and bradycardia

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10
Q

Dysthymia is a chronic mood disorder characterized by depressed mood or anhedonia at least half of the time for at least _______ accompanied by 2 or more vegetative or psychological symptoms and functional impairment.

A

2 years

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11
Q

What are the indications for polysomnography?

A

suspicion of sleep-related breathing disorder, narcolepsy, or sleepwalking, or if pt is pilot or truck driver

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12
Q

Fluoxetine’s brand name.

A

Prozac

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13
Q

Sertraline’s brand name.

A

Zoloft

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14
Q

Which antidepressant has the least sexual side effects and does not cause weight gain?

A

Bupropion

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15
Q

What is a major side effect of mirtazapine?

A

increased appetite

16
Q

What class of drugs includes citalopram?

A

SSRIs

17
Q

What drugs are contraindicated in cocaine-induced myocardial infarction? why?

A

β-blockers; unopposed α activity worsens htn

18
Q

What is the cause of spinal stenosis?

A

narrowing of the spinal canal

19
Q

What are the 2 most common locations of spinal stenosis?

A

cervical and lumbar spine?

20
Q

What are the typical Sx of lumbar spinal stenosis?

A

pain in the low back/buttocks/legs that occurs upon standing and is relieved by sitting or leaning forward