2/12/13

Question 1

What is the pathophysiology of aplastic anemia not due to toxins/drugs?

Answer 1

Killer T-cells attack bone marrow

Question 2

What is the preferred Tx of (non-toxic) aplastic anemia for pts under 50?

Answer 2

BM transplant if there is a donor

Question 3

What is the Tx of (non-toxic) aplastic anemia in pts over 50 or w/o a matched BM donor?

Answer 3

cyclosporine and anti-thymocyte Ig

Question 4

When do you transfuse whole blood?

Answer 4

never!

Question 5

What is the appropriate blood product to administer for anemia?

Answer 5

packed RBCs

Question 6

In pts w/ preexisting disease, hemoglobin should be maintained above a level of ___.

Answer 6

10 g/L

Question 7

What level must hemoglobin be maintatined above in pts w/ no preexisting disease?

Answer 7

7 g/L

Question 8

What kind of heart failure does Chagas disease cause?

Answer 8

systolic and diastolic

Question 9

What is the most common cause of constrictive pericarditis in the Third World?

Answer 9

TB

Question 10

What is the best Tx of hypercalcemia in the acute setting? What is given next?

Answer 10

fluid resuscitation followed by loop diuretics; then treat the underlying cause

Question 11

The gevelopment of a palpable mass in the epigastrium four weeks after the onset of acute pancreatitis is highly suggestive of _______.

Answer 11

pancreatic pseudocyst

Question 12

Why are pancreatic pseudocysts not true cysts?

Answer 12

capsule is fibrotic not epithelial

Question 13

A bluish-grey coloration of the flanks (Grey Turner sign) or periumbilical region (Cullen sign) w/ pancreatic disease indicates what?

Answer 13

hemorrhagic pancreatitis

Question 14

Which cranial nerve is responsible for corneal sensation?

Answer 14

trigeminal

Question 15

What are the typical lung sounds for asbestosis?

Answer 15

fine bibasilar end-inspiratory crackles

Question 16

What is the best diagnostic test for acoustic neuroma?

Answer 16

MRI w/ gadolinium

Question 17

What causes pulsus parvus et tardus?

Answer 17

aortic stenosis

Question 18

What is the most characteristic arrhythmia of digitalis toxicity?

Answer 18

atrial tachycardia w/ variable AV block

Question 19

What is considered a positive induration on PPD test for a normal, healthy person with no risk factors for TB exposure?

Answer 19

> 15 mm

Question 20

What is a positive induration on PPD test for an at-risk person (e.g. healthcare/prison worker, from endemic region, IV drug user, chronic kidney disease, hematologic malignancy, fibrotic lung)?

Answer 20

> 10 mm