2/7/13 b Flashcards
What is the difference in pulmonary capillary wedge pressure (PCWP) between ARDS and CHF?
<18 in ARDS
What is Conn’s syndrome?
primary hyperaldosteronism
What is the bicarb level in Conn’s syndrome? Why?
high; H+ excreted in exchange for Na+
Which type of WBCs will glucocorticoids be most likely to increase?
PMNs
How do glucocorticoids increase serum neutrophil count?
mobilizing the marginated neutrophil pool
How do you define diabetic nephropathy?
albumin:creatinine >30mg/g
What are ythe most common side fx of digoxin toxicity?
GI: anorexia, nausea, vomiting
What is the cause of hypertension in hyperthyroidism?
“hyperdynamic circulation”
Febrile reaction, a common transfusion reaction that is usu. relieved w/ acetaminophen or NSAIDs, is a result of the pt’s plasma reacting with the donor’s _______.
leukocytes
What is the most common type of nephrotic syndrome in adults?
focal segmental glomerulosclerosis
In membranous nephropathy caused by HBV, what deposits in the glomeruli?
HBeAg or the corresponding Ab
What is the classic CSF finding in Guillain-Barre syndrome?
albumino-cytologic dissociation
What is the only medication for ALS?
riluzole
What is the Tx for inflammatory myopathies such as polymyositis and dermatomyositis?
hi-dose corticosteroids
Positive nitrites in a urine dipstick in a pt w/ UTI specifically indicate the presence of _______.
Enterobacteriaciae (e.g. E. coli)
How would you characterize the cervical lymphadenopathy of cancer?
hard and immobile
What are the additional risk factors for focal segmental glomerulosclerosis?
African American, HIV, obesity, and heroin use
What diseases would predispose to amyloidosis?
multiple myeloma and chronic inflammatory disease (e.g. RA)
Tinnitus, fever, tachypnea, nausea, and vomiting are highly suggestive of toxicity with _______.
aspirin (salicylates)
How does aspirin toxicity cause alkalosis?
stimulates respiratory centers
What 2 acid-base abnormalities does salicylate poisoning cause concurrently?
respi alk and meta acid (anion gap)
Fever, tinnitus, and tachypnea should make you suspect what toxicity?
aspirin
What is the most common genetic hypercoagulability disorder?
Factor V Leiden
What is unusual about Factor V in Factor V Leiden?
resistant to inactivation by protein C
Which type of inflammatory arthritis causes dactyltis (“sausage fingers”)?
psoriatic arthritis
What is the most common cutaneous manifestation of sarcoidosis?
erythema nodosum
What is erythema nodosum?
inflammation of the fat cells underneath the skin of both shins
What 3 kinds of meds are used to Tx psoriatic arthritis?
NSAIDs, anti-TNF, and MTX
What kind of drug, used to treat other inflammatory conditions is relatively contraindicated in psoriatic arthritis?
corticosteroids
What is thought to be the pathogenesis of neuropathic arthropathy?
lack of proprioception –> repeated trauma –> destruction of joint
Which group of ppl is neuropathic arthritis seen most commonly in?
diabetics
