2/5/13 Flashcards

1
Q

Loss to follow-up on prospective studies creates a potential for _______ bias.

A

selection

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2
Q

What physical exam finding can easily differentiate methemoglobinemia from carbon monoxide and CN- poisoning?

A

Skin color - pink in CO and CN-, blue in MetHb

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3
Q

Serum levels of ______ will confirm the Dx of CO poisoning.

A

Carboxyhemoglobin

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4
Q

What kind of nephropathy are HBV, HCV, malaria, and syphilis all associated with?

A

Membranous nephropathy

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5
Q

What is hepatorenal syndrome?

A

Renal failure d/t portal htn

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6
Q

In a pt w/ pulmonary embolism, heparin and warfarin should be started simultaneously. After how many days can heparin usu. be stopped?

A

5-7

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7
Q

How long should warfarin be given to a pt after the first PE?

A

6 mos.

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8
Q

How long should warfarin be given to a pt after 2nd PE?

A

For life

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9
Q

In the cause of an out-of-hospital cardiac arrest, when should CPR be started before defibrillation?

A

When >4-5 mins will pass before defibrillator arrives or event was unwitnessed

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10
Q

What aerobic, Gram(+), partially acid-fast branching rods cause pulmonary, CNS, or cutaneous manifestations, particularly in people with deficient cell-mediated immunity?

A

Nocardia

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11
Q

What is the Tx for nocardiasis?

A

TMP-SMX

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12
Q

Electrical alternans is an EKG sign fairly specific for _______.

A

pericardial effusion

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13
Q

What is electrical alternans on EKG? What is thoguht to be the mechanism?

A

amplitude changes from beat to beat as heart swingsback and forth in pericardial fluid.

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14
Q

What benign tumor of the liver causes sheets of enlarged hepatocytes containing lipid and glycogen with loss of hepatic architecture (nodules, bile ducts)?

A

hepatic adenoma

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15
Q

Who is at increased risk for hepatic adenoma?

A

young women w/ a long Hx of oral contraceptive use, anabolic androgen users, glycogen storage disease, DM, and pregnancy

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16
Q

What are the 2 most feared complications of hepatic adenoma?

A

intratumor bleed and malignant transformation

17
Q

What serum marker can indicate malignant transformation ofr hepatic adenoma?

A

alpha-fetoprotein

18
Q

What 2 situations might increased GGT or Alk Phos indicate in pts w/ hepatic adenoma?

A

multiple adenomas or intratumor bleed

19
Q

About ___ in 10 ps w/ hepatic adenoma will experience malignant transformation.

A

1

20
Q

What is the conservative Tx of asymptomatic hepatic adenomas?

A

discontinuation of oral contraceptives followed by serial imaging and measurement of serum AFP.

21
Q

What is the more aggressive Tx of hepatic adenoma, which musdt be performed in symptomatic cases?

A

resection

22
Q

What is a benign hepatic tumor that, unlike adenoma, shows sinusoids and Kupffer cells and is not associated w/ oral contraceptive use?

A

focal nodular hyperplasia (FNH)

23
Q

What assumption is necessary in order to conclude that the exposure-odds ratio is roughly equal to the relative risk?

A

rare disease assumption

24
Q

_______ deficiency can cause RBC fragility, HYPOreflexia, muscle weakness, and blindness.

A

Vit E