general immunology / 1st line of defense Flashcards

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1
Q

plants

A

infection triggers chemical response that destroys infected and adjacent cells, thus localizing the effects

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2
Q

mammals

A

use specific immune response triggered by natural or artificial agents that disrupt dynamic homeostasis

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3
Q

lymphocytes

A

WBC, specific, makes antibodies

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4
Q

monocyte

A

WBC, precursor to macrophages

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5
Q

eosinophils

A

WBC, help break down blood clots and kill parasites

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6
Q

basophils

A

WBC, make histamine, heparin (anticoagulant)

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7
Q

neutrophils

A

WBC, phagocyte

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8
Q

are white blood cells bound the blood vessels?

A

no they can leave and scavenge for pathogens

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9
Q

3 lines of defense

A
  1. skin/mucous membranes (nonspecific & innate)
  2. inflammatory response / wound healing (nonspecific and innate)
  3. acquired immune system (specific)
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10
Q

skin

A

1st line, oily and acidic (pH 3-5), lysozyme

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11
Q

saliva/tears

A

1st line, lysozyme

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12
Q

cilia

A

1st line - in respiratory tract, sweeps out invaders in our throat as we swallow them

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13
Q

stomach

A

1st line, acidic (pH 2)

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14
Q

birth canal

A

1st line, acidic

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15
Q

nose hairs

A

1st line, filter the air we breathe

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16
Q

symbiotic bacteria

A

1st line, good bacteria that competes with bad

17
Q

mucous membrane

A

1st line, traps microbes

18
Q

lysozyme

A

enzymes capable of inhibiting or killing microbes

19
Q

antibiotics

A

chemicals derived from bacteria and fungi, only works on bacteria

20
Q

vaccines

A

stimulate B cells, you are exposed to actual viruses that are inactivated or fragmented. some are synthetic. if you come into contact with the real thing you can start an immune response before it does any damage

21
Q

autoimmune disease

A

when the immune system turns against its own bodies cells. rheumatoid arthritis (attack bone/cartilage), lupus (DNA), MS (myelin sheaths)

22
Q

immunodeficiency diseases

A

all or part of the immune system is lacking

23
Q

stress

A

can decrease immune activity

24
Q

allergies

A

abnormal sensitivity to antigens in our environment, children exposed to cigarette smoke are more likely to develop allergies. When exposed to the same allergens over and over, it causes a greater and greater release of histamine. This eventually causes allergy symptoms.

25
Q

epitope

A

antigenic determinant (where Ab binds)