general immunology / 1st line of defense Flashcards
plants
infection triggers chemical response that destroys infected and adjacent cells, thus localizing the effects
mammals
use specific immune response triggered by natural or artificial agents that disrupt dynamic homeostasis
lymphocytes
WBC, specific, makes antibodies
monocyte
WBC, precursor to macrophages
eosinophils
WBC, help break down blood clots and kill parasites
basophils
WBC, make histamine, heparin (anticoagulant)
neutrophils
WBC, phagocyte
are white blood cells bound the blood vessels?
no they can leave and scavenge for pathogens
3 lines of defense
- skin/mucous membranes (nonspecific & innate)
- inflammatory response / wound healing (nonspecific and innate)
- acquired immune system (specific)
skin
1st line, oily and acidic (pH 3-5), lysozyme
saliva/tears
1st line, lysozyme
cilia
1st line - in respiratory tract, sweeps out invaders in our throat as we swallow them
stomach
1st line, acidic (pH 2)
birth canal
1st line, acidic
nose hairs
1st line, filter the air we breathe
symbiotic bacteria
1st line, good bacteria that competes with bad
mucous membrane
1st line, traps microbes
lysozyme
enzymes capable of inhibiting or killing microbes
antibiotics
chemicals derived from bacteria and fungi, only works on bacteria
vaccines
stimulate B cells, you are exposed to actual viruses that are inactivated or fragmented. some are synthetic. if you come into contact with the real thing you can start an immune response before it does any damage
autoimmune disease
when the immune system turns against its own bodies cells. rheumatoid arthritis (attack bone/cartilage), lupus (DNA), MS (myelin sheaths)
immunodeficiency diseases
all or part of the immune system is lacking
stress
can decrease immune activity
allergies
abnormal sensitivity to antigens in our environment, children exposed to cigarette smoke are more likely to develop allergies. When exposed to the same allergens over and over, it causes a greater and greater release of histamine. This eventually causes allergy symptoms.