embryology Flashcards

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1
Q

stages of development

A

egg&sperm –> fertilization –> cleavage –> gastrulation –> organogenesis –> metamorphosis

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2
Q

cleavage

A

division of zygote into smaller cells every 12-24 hours

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3
Q

morula

A

solid ball of cells

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4
Q

blastula

A

hollow ball of cells

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5
Q

gastrulation

A
  • the movement of cells to create germ layers
  • starts at dorsal lip
  • results in gastrula
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6
Q

3 germ layers

A

ectoderm, mesoderm, endoderm

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7
Q

ectoderm

A

skin, nervous system, teeth, lens

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8
Q

mesoderm

A

blood, skeletal, muscular, circulatory, and lymphatic system

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9
Q

endoderm

A

linings of respiratory, excretory, reproductive, and digestive system

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10
Q

deuterosomes

A

anus first

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11
Q

protostomes

A

mouth first

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12
Q

differentiation

A
  • all cells have the same genes
  • due to the expression or silencing of genes for specific proteins, determined by location of cells, and signaled by the environment
  • signals are the same for many organisms
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13
Q

noggin and chordin

A

induce mesoderm to change to muscle and notochord (spine)

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14
Q

retinoic acid

A

regulates limb development and regeneration

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15
Q

homeotic selector genes

A
  • genes whose expression affects the overall body plan / sequences
  • bithorax/antennapedia are due to mutations in drosophila
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16
Q

lineage map

A
  • tracing the cells during development and creating a map

- allows us to know what cells will become what structures

17
Q

organogenesis

A
  • organ formation begins

- apoptosis and gene activation/silencing are very important

18
Q

apoptosis

A

hollows out blood vessels, creates fingers and toes, necessary for proper brain development and more

19
Q

complete metamorphosis

A
egg
larva
pupa
adult
butterfly, mosquito, beetles, frogs
20
Q

aging

A
  • depends on genes and environment

- as we age our cells are less likely to divide and more likely to die

21
Q

embryonic stem cell retrieval

A

~100 cells total

blastocyst