General anesthetics Flashcards
State characterized by analgesia, amnesia, LOC, inhibition of reflexes, and skeletal muscle relaxation
State of general anesthesia
Stages of general anesthesia
Analgesia
Excitement
Surgical anesthesia
Medullary depression
Concentration of inhaled anesthetic which produces immobility in 50% of subjects exposed to a noxious stimulus
Minimum alveolar concentration
MAC where nearly 100% of subjects will not respond to stimuli
1.3 MAC
Toxicity of nitrous oxide
Second gas effect
Diffusion hypoxia
Inhaled general anesthetics associated with nephrotoxicity
Methoxyflurane
Enflurane
Sevoflurane
Treatment for malignant hyperthermia
Dantrolene
Toxicity of halothane
Sensitizes the heart to epi-induced arrhythmias
Halothane induced hepatitis
Inhaled general anesthetic commonly used for induction in children
Halothane
Most rapid onset of action and recovery of the halogenated general anesthesias
Desflurane
Side effects of desflurane
Irritating to airway in awake pts, causing coughing, salivation, and bronchospasm
Types of barbiturate general anesthetics
Thiopental
Methohexital
Side effects of barbiturates
Cerebral metabolism, oxygen utilization, and cerebral blood flow decreased
Prcipitate porphyria
Used as premedication prior to induction of general anesthesia, producing anxiolysis, amnesia, and sedation
Benzodiazepines
Benzodiazepine with a a more rapid onset and shorter elimination half-life
Midazolam
General anesthetic agent of choice in ambulatory surgery
Propofol
Agent effective in producing prolonged sedation in pts in critical care
Propofol
General anesthetic with little effect on CV and respiration, used in pts with CAD, cardiomyopathy, cerebra vascular disease, and hypovolemia
Etomidate
Side effects of etomidate
Post-op nausea
Adrenocortical suppression
Neuroleptanalgesia
State of analgesia and amnesia caused by combining fentanyl and droperidol
Dissociative anesthetic that produces a cataleptic state that includes analgesia and amnesia
Ketamine
General anesthetic that causes CVS stimulation
Ketamine
Emergence phenomena of ketamine
Post-op disorientation
Sensory and perceptual illusions
Vivid dreams