Encephalitis Flashcards
Cause of epidemic encephalitis
West Nile virus
Encephalomyelitis
Encephalitis with simultaneous involvement of spinal cord
General symptoms of encephalitis
HA, mild
Fever
Altered mentation
Focal neurologic deficit
Most common cause of sporadic encephalitis in the US
HSV-1
Positive sense, enveloped, ssRNA ARBOvirus of the flaviviridae family
West Nile virus
Vector of West Nile virus
Culex mosquito
Reservoir host for West Nile virus
Birds
Pt presents with flaccid paralysis, hyporeflexia, muscle weakness, tremors, ataxia, fever, and HA after spending time outdoors
West Nile virus encephalitis
DWI MRI reveals restricted diffusion in L or R medial temporal lobe
HSV I encephalitis
Treatment for HSV 1 encephalitis
Acyclovir
Envelopled, negative sense, ssRNA in a bullet-shaped capsule
Rabies
Primary source of rabies in US
Bats
Negri bodies
Eosinophilic cytoplasmic inclusions seen in rabies
Passive immunization after rabies exposure
Inject hyperimmune anti-rabies gamma globulin around wound site
Active immunization for rabies
5 doses of human diploid cell vaccine (HDCV)