Genera Vibrio, Campylobacter and Helicobacter Flashcards
1
Q
What taxonomy is Campylobacterales
A
- Order
2
Q
What is the general morphological and biochemical characteristics of Campylobacteraceae
A
- 3 genera
- Gram negative spiral shaped
- Microaerophilic
- Oxidase positive
- Catalase positive
- Nitrate reductase positive
- motile
3
Q
what is the genera of Campylobacteraceae
A
- Campylobacter
- Helicobacter
4
Q
What is the clinical symptoms of Campylobacter jejuni
A
- day 1-3 fever, vomiting, headaches
- day 3 watery/bloody diarrhoea with abdominal pain; stools contain inflammatory cells and colonic biopsies
5
Q
What are the steps in infection for Campylobacter jejuni
A
- Ingestion of bacteria
- reaches small intestine
- mucosal damage
- invades via transcellular and paracellular routes
- provokes an immune response
- virulence gene expression
- eventually cleared from host
6
Q
What is campylobacter jejuni virulence factors
A
- motility (flagella)
- lipooligosaccharide (LOS) and capsule
- colonisation and invasion (e.g. outer membrane adhesions)
- toxin production
7
Q
What is the main reservoir of campylobacter spp.
A
- Chickens
8
Q
What is the highest rate of Helicobacter pylori ?
A
- Africa (79.1%)
9
Q
What is the route for Helicobacter pylori
A
- Oral, mainly spread by intrafamilial transmissions
10
Q
Name some Helicobacter pylori virulence factors
A
- urease production
- flagella / motility
- adhesins
- toxins
11
Q
What taxonomy is Virbrionales
A
Order-
12
Q
what is the general morphological and biochemical characteristics of Vibrionaceae
A
- 4 genera
- gram negative straight / curved rod
- Facultative anaerobe
- Oxidase positive (most)
- Catalase positive
- Nitrate reducatase positive
13
Q
Name a genera for Vibrionales
A
- Vibrio
14
Q
Name some species of Vibrio
A
- cholerae, parahaemolyticus, vulnificus
15
Q
What is the disease of Vibrio cholerae
A
- diarrhoeal infection caused by igestion of food or water contaminated with the bacterium
