Chlamydia and Rickettsia pt. 2 Flashcards
1
Q
What does Legionella pneumophila cause
A
- Legionaire’s disease
2
Q
What does Bordetella pertussis cause
A
- Whooping cough
3
Q
What does Haemophilus influenzae cause
A
- meningitis and septicaemia in children < 6 months
4
Q
What is the characteristics of Legionella pneumophila
A
- non spore forming, gram negative rods that form short thin forms to longer filamentous forms
- motile via a single polar flagellum
- aerobic
- grow in tap water and water
5
Q
What is the most common form of transmission for Legionella
A
- inhalation of contaminated aerosols produced in conjunction with water sprays, jets or mists
6
Q
Explain Legionnaire’s disease
A
- acute pneumonia. Bacterium multiplies in alveolar macrophages
- produce cytokines that elict an influx of monocyte and polymorphonuclear cells
- obliteration of the air spaces compromises respiratory function
- fevers, cough, breathlessness
7
Q
Explain the chain of causation for legionella infection
A
- enviornmental reservoir ->
- multiplication (stagnation, temperature nutrients) ->
- Dissemination by aerosol generation (running tap, shower, toilet flush, spraying flowers, jacuzzis, cooling towers etc) ->
- inhalation into lungs by suseptible host (age, sex, etc)
8
Q
What are the general characteristics for bordetella pertussis
A
- aerobic, gram negative, small coccobacillus, specific to humans only, colonizes the respiratory tract to cause whooping cough
9
Q
What is the transmission to bordatella pertussis
A
- transmission via droplets, inhalation
10
Q
What happens in whooping cough
A
- colonisation of the bacteria in the upper respiratory tract, production of toxins
- forceful, hacking successive coughs
- title time for breating
- whoop when air rushes back into the lungs
11
Q
A