Chlamydia and Rickettsia pt. 2 Flashcards

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1
Q

What does Legionella pneumophila cause

A
  • Legionaire’s disease
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2
Q

What does Bordetella pertussis cause

A
  • Whooping cough
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3
Q

What does Haemophilus influenzae cause

A
  • meningitis and septicaemia in children < 6 months
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4
Q

What is the characteristics of Legionella pneumophila

A
  • non spore forming, gram negative rods that form short thin forms to longer filamentous forms
  • motile via a single polar flagellum
  • aerobic
  • grow in tap water and water
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5
Q

What is the most common form of transmission for Legionella

A
  • inhalation of contaminated aerosols produced in conjunction with water sprays, jets or mists
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6
Q

Explain Legionnaire’s disease

A
  • acute pneumonia. Bacterium multiplies in alveolar macrophages
  • produce cytokines that elict an influx of monocyte and polymorphonuclear cells
  • obliteration of the air spaces compromises respiratory function
  • fevers, cough, breathlessness
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7
Q

Explain the chain of causation for legionella infection

A
  • enviornmental reservoir ->
  • multiplication (stagnation, temperature nutrients) ->
  • Dissemination by aerosol generation (running tap, shower, toilet flush, spraying flowers, jacuzzis, cooling towers etc) ->
  • inhalation into lungs by suseptible host (age, sex, etc)
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8
Q

What are the general characteristics for bordetella pertussis

A
  • aerobic, gram negative, small coccobacillus, specific to humans only, colonizes the respiratory tract to cause whooping cough
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9
Q

What is the transmission to bordatella pertussis

A
  • transmission via droplets, inhalation
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10
Q

What happens in whooping cough

A
  • colonisation of the bacteria in the upper respiratory tract, production of toxins
  • forceful, hacking successive coughs
  • title time for breating
  • whoop when air rushes back into the lungs
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11
Q
A
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