Chlamydia and Rickettsia Flashcards

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1
Q

What taxonomy is Chlamydiaceae?

A
  • Phylogeny
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2
Q

What are the two genera of Chlamydiaceae?

A
  • Chlamydia and Chlamydophila
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3
Q

What are the two Chlamydal Morphologies

A
  • Elementary bodies (EB)
  • Reticular bodies (RB)
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4
Q

What are Elementary bodies?

A
  • infectious form, metabolically inactive, electron dense, nucleoid, granular cytoplasm, spherical, approx 0.2-0.3 microns in diameter
  • one of the chlamydial morphologies
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5
Q

What are Reticular bodies (RB)

A
  • intracellular reproductive form, metabolically active, chromatin dispersed (transcription)
  • approx 0.5-2 microns in diameter, can divide by binary fission resulting in new RBs
  • chlamydial morphologies
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6
Q

What are the general features of Chlamydiaceae

A
  • Non-motile, obligate intracellular coccoid bacilli
  • inhabit epithelial cells/macrophages
  • energy parasites: lack ATP-generating ability and must obtain from host cell
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7
Q

What is the most common preventable cause of blindness

A
  • Chlamydia trachomatis
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8
Q

What is Chlamyda Trachomatis types A, B and C

A
  • Infection of conjunctival epithelial cells, repeated clinical/subclinical infection and cell infiltration can cause cornea to cloud/scar
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9
Q

How is Chlamydia Trachomatis types A, B and C transmitted

A
  • by flies, fomites, touch
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10
Q

A Patient lives in a HOT, DRY CLIMATE and has symptoms on their eyes such as CORNEAL OPACITY, TRACHOMATOUS SCARRING and TRACHOMATOUS TRICHIASIS, what specific disease does he have

A
  • Chlamydia Trachomatis types A, B , C
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11
Q

What are the two different forms of Chlamydia Trachomatis Types D to K

A
  • Neonatal and Adult form
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12
Q

Explain the neonatal form of Chlamydia trachomatis

A
  • Inclusion blenorrhoea can develop when infant is in birth canal and appears 5-12 days after birth
  • can precede infant pneumonia (can also develop independenty)
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13
Q

Explain the adult form of chlamydia trachomatis

A
  • Associated with sexual contact via STD form, also from swimming pools contaminated with chlamydia from genital secretions (“swimming pool conjunctivitis”)
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14
Q

Explain the Genital chlamydiasis in men

A
  • urethritis (NGU), 7-28 days after infection, mild burning, more frequent need to urinate, white discharge from penis
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15
Q

Explain the Genital chlaydiasis in women

A
  • Urethritis, cervicitis, PID, infertility, ectopic pregnancy, premature delivery, postpartum fever, LGV
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16
Q

What causes parrot fever

A
  • Chamydia psittaci
17
Q

What are the risk groups for parrot fever

A
  • occupational disease, pigeon farmers, pet shop owners, veterinarians, poultry workers etc
18
Q

What taxonomy is Rickettsiae?

A
  • Phylogeny
18
Q

What taxonomy is Rickettsia

A
  • genera
19
Q

What is Typhus caused by

A
  • Rickettsia prowazekii
20
Q

Patient x has been infected by a disease by faeces. after 7-14 days, patient x suffers from hgih fever, chills, headaches, and a coma, what disease does he have

A
  • Typhus
21
Q

What is the difference between Typhus and Typhoid

A
  • Typhus: caused by Rickettsia typhi or proowzekii. Vectors: flea, Prevention: good hygiene and insect repellants, insecticides
  • Typhoid: caused by Salmonella typhi. Vectors: contaminated food, Prevention: good hygiene, vaccine
22
Q
A