Chlamydia and Rickettsia Flashcards
What taxonomy is Chlamydiaceae?
- Phylogeny
What are the two genera of Chlamydiaceae?
- Chlamydia and Chlamydophila
What are the two Chlamydal Morphologies
- Elementary bodies (EB)
- Reticular bodies (RB)
What are Elementary bodies?
- infectious form, metabolically inactive, electron dense, nucleoid, granular cytoplasm, spherical, approx 0.2-0.3 microns in diameter
- one of the chlamydial morphologies
What are Reticular bodies (RB)
- intracellular reproductive form, metabolically active, chromatin dispersed (transcription)
- approx 0.5-2 microns in diameter, can divide by binary fission resulting in new RBs
- chlamydial morphologies
What are the general features of Chlamydiaceae
- Non-motile, obligate intracellular coccoid bacilli
- inhabit epithelial cells/macrophages
- energy parasites: lack ATP-generating ability and must obtain from host cell
What is the most common preventable cause of blindness
- Chlamydia trachomatis
What is Chlamyda Trachomatis types A, B and C
- Infection of conjunctival epithelial cells, repeated clinical/subclinical infection and cell infiltration can cause cornea to cloud/scar
How is Chlamydia Trachomatis types A, B and C transmitted
- by flies, fomites, touch
A Patient lives in a HOT, DRY CLIMATE and has symptoms on their eyes such as CORNEAL OPACITY, TRACHOMATOUS SCARRING and TRACHOMATOUS TRICHIASIS, what specific disease does he have
- Chlamydia Trachomatis types A, B , C
What are the two different forms of Chlamydia Trachomatis Types D to K
- Neonatal and Adult form
Explain the neonatal form of Chlamydia trachomatis
- Inclusion blenorrhoea can develop when infant is in birth canal and appears 5-12 days after birth
- can precede infant pneumonia (can also develop independenty)
Explain the adult form of chlamydia trachomatis
- Associated with sexual contact via STD form, also from swimming pools contaminated with chlamydia from genital secretions (“swimming pool conjunctivitis”)
Explain the Genital chlamydiasis in men
- urethritis (NGU), 7-28 days after infection, mild burning, more frequent need to urinate, white discharge from penis
Explain the Genital chlaydiasis in women
- Urethritis, cervicitis, PID, infertility, ectopic pregnancy, premature delivery, postpartum fever, LGV