Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

First Aid Pharmacology > Gastrointestinal System > Flashcards

Gastrointestinal System Flashcards

1
Q

name the four H2 blockers

A

Cimetidine
Ranitidine
Famotidine
Nizatidine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

H2 Blockers (Cimetidine, Ranitidine, Famotidine, NIzatidine)

MOA
Use
UDE

A
  • reversibly block H2 receptors and decreases H+ secretion by parietal cells
    -peptic ulcer, gastritis and esophageal reflux
    -Cimetidine decreases libido in men and inhibits P450 and can crosse placenta and BBB
    Ranitidine and Cimetidine decreases renal excretion of creatinin
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

name some PPU

A

omeprazole
lansoprazole
esomeprazole

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

PPI

MOA
Use
UDE

A
  • irreversibly inhibit H+/K+ in stomach parietal cells
  • peptic ulcer and gastritis
  • risk of C diff infection and decrease calcium and can cause osteoporosis
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

UDE of the antacid aluminum hydroxide

A

constipation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Bismuth and Sucralfate (peptobismol)

MOA
Use
UDE

A
  • bind to the ulcer base and provide protection (secrete HCO3)
  • increase ulcer healing
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

misoprostol

MOA
Use
UDE

A
  • PGE1 analogue increases secretion of gastric mucous
  • prevention of NSAID damage, maintains PDA
  • Diarrhea
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Ocreotide

MOA
Use
UDE

A

Somatostatin analogue (long acting)

  • acromegaly, acute viral bleeds, VIPoma and carcinoid tumors
  • risk of gall stones due to the inhibition go CCK
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Magnesium Hydroxide, Magnesium Citrate, Polyethylene Glycol and Lactulose

MOA
Use
UDE

A

OSMOTIC LAXATIVES

- provides osmotic pull
- constipaiton
lactulose treats hepatic encephalopathy
- diarrhea

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Sulfasalazine

MOA
Use
UDE

A

combined with sulfapyridine ( antibacterial) and 5- aminosalicyclic acid

  • ulcerative colitis and crohns
  • sulfonamide toxicity and reversible oligospermia
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Loperamide

MOA
Use
UDE

A
  • agonist at u opioid receptors that slows gut motility
  • diarrhea
  • constipation
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

ondansetron

MOA
Use
UDE

A
  • 5HT3 antagonist, decreases vagal stimulation (antiemetic-powerful)
  • controls post op vomiting and people on chemo
  • QT prolongation
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Metoclopramide

MOA
Use
UDE

A
  • D2 receptor antagonist, increases resting tone, LES tone and motility
  • post surgery gastroparesis
  • don’t give to people with small bowl obstruction or Parkinsons because of the D2 blockade
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Orlistat

MOA
Use
UDE

A
  • inhibits gastric and pancreatic lipase (decreases the breakdown and absorption of dietary fats)
  • weight loss
  • steatorrhea
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Ursodiol

MOA
Use
UDE

A

non toxic bile acid that increases bile secretion and decreases cholesterol secretion and reabsorption

  • primary biliary cirrhosis ad gallstone prevention
How well did you know this?
1
Not at all
2
3
4
5
Perfectly

First Aid Pharmacology (13 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions