Bichem Flashcards

1
Q

Ouabain inhibits what

A

K+ site by binding to it

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2
Q
Bone
Skin
Tendon
Dentin
Fascia Lata
And cornea 

Name that collagen

A

Type 1

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3
Q

Name that collagen

Cartilage
Vitreous body
Nucleus pulpsous

A

Type 2

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4
Q

Name that collagen

Reticulin 
Blood vessels
Uterus
Fetal tissue 
Granulation tissue
A

Type 3

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5
Q

Name that collagen

Basement membrane

A

Type 4

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6
Q

Owls eye inclusion

A

CMV

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7
Q

Negri bodies

A

Rabies

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8
Q

Cowdry bodies

A

Herpes

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9
Q

Lewy bodies

A

Parkinson’s

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10
Q

Bronchiectasis
Situs in versus
Recurrent sinusitis

A

Kartageners syndrome

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11
Q

6 steps to collagen synthesis

A
  1. Synthesis - translation of collagen alpha chains (preprocollagen)
  2. Hydroxylation - of proline and lysine
  3. Glycosylation
  4. Exocytosis
  5. Proteolytic processing
  6. Cross liking
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12
Q

Osteogenesis imperfecta has what two common genetic defects

A

Col1A1

Col1A2

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13
Q

Form of osteogenesis imperfecta where child dies in uterine and it is autosomal recessive

A

Type 2

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14
Q

Vascular type of ED has a problem with what

A

Type 3 collagen

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15
Q

What is the mutated gene in ED type 4

A

Lysyl hydroxylase

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