Gastrointestinal Drugs QUIZ

Question 1

NSAIDs cause gastric ulcers by which mechanism:
1. increase gastric acid production
2. all of the choices are correct
3. decrease bicarbonate buffers
4. block mucous production by prostaglandins

Answer 1

2. all of the choices are correct

Question 2

Which OTC (over-the-counter) intestinal protectant changes feces to a black color?
1. Ranitidine (Zantac)
2. Bismuth subsalicylate (Peptobismal)
3. Calcium carbonate (Tums)
4. Omeprazole (Prilosec)

Answer 2

2. Bismuth subsalicylate (Peptobismal)

Question 3

Opiate-related drugs (such as loperamide) control diarrhea by which mechanism?
1. Antibiotic activity agains anaerobes
2. Inhibit parasympathetic nervous system
3. Presence of insoluble fiber
4. Decreasing peristalsis & increasing segmental contractions

Answer 3

4. Decreasing peristalsis & increasing segmental contractions

Question 4

Histamine-2 receptor antagonists (H2 Blockers) function by:
1. none of the choices is correct
2. inhibit histamine induced HCl acid production
3. increasing bicarbonate buffering
4. adhere to the ulcer to speed healing

Answer 4

2. inhibit histamine induced HCl acid production

Question 5

Which class of antiemetic has the side effect of hypotension?
1. NK-1 Receptor Antagonist (Cerenia)
2. Procainamide derivatives (Metoclopramide)
3. Antihistamines (Dramamine)
4. phenothiazine derivatives (Chlorpromazine)

Answer 5

4. phenothiazine derivatives (Chlorpromazine)

Question 6

Centrally acting emetics (apomorphine) work by:
1. stimulate dopamine receptors in the chemoreceptor trigger zone (CRTZ)
2. paralyzing the vestibular apparatus
3. chemical irritation of the pylorous
4. activating the parasympathetic nervous system

Answer 6

1. stimulate dopamine receptors in the chemoreceptor trigger zone (CRTZ)

Question 7

Proton-pump Inhibitors (omeprazole, Nexium) treat ulcers by:
1. preventing the parietal cell from making HCl
2. improving liver function
3. increasing gastric motility
4. preventing gastrin release

Answer 7

1. preventing the parietal cell from making HCl

Question 8

Before inducing vomiting, the veterinary team must evaluate the patient for contraindications.
List 3 possible contraindications for inducing emesis.

Answer 8

1. If a caustic substance has been ingested
2. Stomach or esophagus is at risk to rupture
3. Decreased consciousness or unconscious

Question 9

Diarrhea is caused by an imbalance of fluid secretion and fluid reabsorption in the intestinal tract.
Name two possible mechanisms for this imbalance to occur.

1. Exudative

Answer 9

1. Malabsorption (ex: parvo)
2. Osmotic

Question 10

Dr. Smith (DVM) has diagnosed Giardia in Brandy Johnson (canine). If the dose is 25mg/kg BID for 5 days, and Brandy weighs 45#; how many 500mg tablets will you dispense for Brandy?
a. 20
b. 5
c. 10
d. 40

Answer 10

c. 10