Gallbladder Flashcards

1
Q
A
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2
Q

Cholelithiasis

A

stones in the gallbladder from impaired metabolism of cholesterol, bilirubin, and bile acids

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3
Q

Types of cholelithiasis

A

Cholesterol, pigmented, mixed stones

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4
Q

Cholelithiasis patho

A

Crystals saturate with bile and sit and form stones

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5
Q

Risk factors for cholelithiasis

A

Obese, female, middle ages (around 40), oral contraceptives, rapid wt loss, indigenous Americans or white people, genetic predisposition, pancreatic/lipase disease

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6
Q

What are CM for cholelithiasis based on?

A

Severity and location of the obstruction

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7
Q

When will cholelithiasis be asymptomatic

A

If stones are just in the gallbadder

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8
Q

CM of cholelithiasis

A

Epigastric and RUQ pain, intolerance to fatty foods, heartburn, flatulence, epigastric discomfort, biliary colic, jaundice, dark amber urine that foams when shaken, clay colored stool, steatorrhea, pruritis, bleeding

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9
Q

Why does cholelithiasis cause epigastric pain

A

when stones are lodged in the cystic duct or common bile duct

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10
Q

Why does cholelithiasis cause intolerance to fatty foods and cabbage?

A

no bile in small intestine to help with digestion

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11
Q

When does biliary colic occur after eating fatty meals

A

30 minutes to several hours after eating fatty meals

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12
Q

Why does cholelithiasis cause jaundice

A

When stones are lodged in the bile duct so bile can’t flow into the duodenum

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13
Q

Why does cholelithiasis cause dark amber urine

A

Conjugated bilirubin builds up into the blood and solube bile seeps into the urine

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14
Q

Why does cholelithiasis cause clay colored stools

A

bilirubin can’t reach the small intestine to convert into urobilogen which is what usually gives stool its brown color

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15
Q

Steatorrhea

A

Occurs when there are no bile salts in the duodenum to prevent fat digestion

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16
Q

Why does cholelithiasis cause pruritis

A

bile salts deposit in the skin

17
Q

Why does cholelithiasis cause bleeding

A

there is decreased absorption of vitamin K when bile is not present

18
Q

Cholecystitis

A

acute or chronic inflammation and distention of the gallbladder

19
Q

What is often the cause of cholecystitis

A

Gallstones are lodged in the cystic duct

20
Q

Is pain with cholecystitis common?

A

Yes, pain is similar to that of biliary colic and cholelithiasis

21
Q

Complications of distention of the wall of the gallbladder

A

decrease BF, ischemia, necrosis, perforation

22
Q

Sx of cholecystitis

A

Abdominal distention, fever, leukocytosis, guarding, rebound tenderness, inc alk phos and bilirubin

23
Q

What is the biggest risk with cholecystitis

A

Pressure on the distended wall of the gallbladder

24
Q

Which sx are different between cholelithiasis and cholecystitis

A

Cystitis has fever, leukocytosis, guarding, and rebound tenderness and lithiasis doesn’t

25
Q

What can cholecystitis lead to

A

scarring

26
Q

What is often the tx for cholecystitis

A

Removal

26
Q

Drug pharm for cholecystitis

A
  • Ketorolac (NSAIDs) or opioids
  • antiemetic for n/v
  • anticholinergics
  • bile acids
26
Q

Bile acids for cholecystitis

A

dissolve stones; often used if pt can’t have surgery

26
Q

How do anticholinergics help with cholecystitis

A

they dec gallbladder secretions and stop spasms that might lodge more stones in the ducts