G&E: Linkage and Epistasis COPY Flashcards
Sex-linked characteristics
The allele that codes for it is located on a sex chromosome.
Why are males more likely to show recessive phenotypes for genes that are sex-linked?
- Most genes on sex chromosomes are only carried on the X chromosome.
- Males only have one X chromosome and so often only have one allele for sex-linked genes.
- As they only have one copy, they express the characteristic even if it is recessive.
Why is colour blindness much rarer in women than men?
Sex-linked disorder.
Males only need one copy of the recessive allele to be colourblind, while females need two.
Autosome
Chromosome that isn’t a sex chromosome.
Autosomal linkage
When two genes are on the same chromosome so stay together during the independent segragation of chromosomes in meiosis I.
Epistasis
When the allele of one gene mask the expression of the alleles of other genes.
What is the phenotypic ratio of a dihiybrid cross involving a recessive epistatic allele?
2 homozygous parents
9:3:4
dominant both : dominant epistatic recessive other : recessive epistatic
What is the phenotypic ratio of a dihydrib cross involving a dominant epistatic allele?
2 homozygous parents
12 : 3 : 1
dominant epistatic : recessive epistatic dominant other : recessive both