E&T: Gas Exchange in Humans Flashcards

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1
Q

Describe the key components of the human gas exchange system:

A
  • Trachea
  • Splits into bronchi - one enters each lung
  • Each branches off into bronchioles
  • End in alveoli
  • Ribcage, intercostal muscles and diaphragm work together to move air in and out
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2
Q

What are the two layers of intercostal muscle called?

A

Internal and external

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3
Q

What are the two stages of ventilation?

A

Inspiration and expiration

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4
Q

Describe inspiration:

A
  • External IM and diaphragm contract (internal relaxes)
  • Ribcage moves upwards and outwards
  • Diaphragm flattens
  • Increases volume of thoracic cavity
  • This decrease lung pressure below atmospheric pressure
  • Air flows down trachea and into lungs

Active process!

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5
Q

Is inspiration active or passive?

A

Active

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6
Q

Describe normal expiration

A
  • External IM and diaphragm relax
  • Ribcage moves downwards adn inwards
  • Diaphragm curves
  • Decreases thoracic cavity
  • Lung pressure increases above atmospheric
  • Air forced down pressure gradient and out of lungs

Passive!!

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7
Q

Describe forced expiration

A
  • External intercostal muscles relax
  • Internal muscles contract
  • Pulls ribcage further down and in
  • This is antagonistic - opposite
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8
Q

Where does gas exchange happen in humans?

A

Alveoli

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9
Q

What is each alveoli made from?

A

Single layer of thin, flat cells called alveolar epithelium

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10
Q

Describe gas exchange in alveoli:

A
  • Alveoli increase SA and are surrounded by capillaries
  • O2 diffuses out of alveoli, across alveolar epithelium and capillary endothelium into haemoglobin.
  • CO2 diffuses into alveoli from blood and is breathed out.
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11
Q

Briefly summarise gas exchange in humans:

A
  • O2 moves down trachea, bronchi and bronchioles in to alveoli.
  • Happens down a pressure gradient.
  • In alveoli, O2 diffuses across alveolar epithelium, capillary endothelium and into capillary.
  • Happens down a diffusion gradient.
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12
Q

How are the alveoli adapted for gas exchange?

A
  • Thin exchange surface - alveolar epithelium is one cell thick - short diffusion pathway.
  • Large surface area - due to large number of alveoli.
  • Steep concentration of O2 and CO2 between alveoli and capillaries - increase rate of diffusion.
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