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MMD1047 > Fungus > Flashcards

Fungus Flashcards

1
Q

What are the ideal targets for antifungal drugs

A

You would want to target components of fungi that are proper to fungi for example
Membrane cellulaire -> Ergostérol
Paroi cellulaire -> Chitine, glucans

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2
Q

What are dimorphe fungi

A

These are fungi that can be either LEVURES OR FILAMENTEUX depending on the temperature

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3
Q

Describe the morphological classification of fungi
Draw it

A

Fungi ->
macroscopique = champignon
microscopic:
levure, dimorphe, filamenteux

filamenteux:
Hyphomycètes
(Hyphes septés)
Mucorales = Zygomycètes
(Hyphes non septés

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4
Q

What type of fungi is Mucorales = Zygomycètes

A

Filamenteux: Hyphes non septés

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5
Q

What type of fungi is Hyphomycètes

A

Filamenteux: Hyphes septés

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6
Q

3 types of Levures

A

Candida
Cryptococcus
Malassezia

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7
Q

3 type of Dimorphiques

A

Histoplasma
Blastomyces
Coccidioides

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8
Q

2 big families of Filamenteux

A

Hyphomycètes
Mucorales (Zygomycètes)

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9
Q

What family does this go :
Aspergillus

A
  • Filamenteux
  • Hyphomycètes
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10
Q

What family are those:
* Rhizopus
* Mucor

A

Mucorales (Zygomycètes) -> filamenteaux

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11
Q

What type is Pneumocystis

A

Autres

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12
Q

What do we target and how do we kill using Azolés

A

Target Ergostérol
Action: Inhibition de la synthèse de
l’ergostérol

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13
Q

What do we target and how do we kill using Allylamines

A

Target Ergostérol
Action: Inhibition de la synthèse de
l’ergostérol

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14
Q

What do we target and how do we kill using Polyènes

A

Target Ergostérol
Action: Interaction directe avec l’ergostérol modifiant la perméabilité de la membrane

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15
Q

What do we target and how do we kill using Échinocandines

A

Target Paroi
Action: Inhibition de la synthèse du
glucan

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16
Q

Mycoses superficielles et profondes cause what?

A

Infections

17
Q

Organisme cause directement le dommage. WHich one:
Mycotoxicoses
Mycoses superficielles et profondes
Syndromes d’hypersensibilité

A

Mycoses superficielles et profondes
+
Mycotoxicoses

18
Q

Organisme cause allergies. WHich one:
Mycotoxicoses
Mycoses superficielles et profondes
Syndromes d’hypersensibilité

A

Syndromes d’hypersensibilité

19
Q

Organisme does not invade the tissue. WHich one:
Mycotoxicoses
Syndromes d’hypersensibilité

A

Both of them

20
Q

Organisme cause Empoisonnement. WHich one:
Mycotoxicoses
Mycoses superficielles et profondes
Syndromes d’hypersensibilité

A

Mycotoxicoses

21
Q

Organisme doesnt cause damage itself The host does. WHich one:
Mycotoxicoses
Syndromes d’hypersensibilité
Mycoses

A

Syndromes d’hypersensibilité

22
Q

Candida auris
Give niche, colonising spots, wher ewe find it, resistancy level, presence in quebec

A

Niche écologique peu connue (environnementale ?)
Colonise la peau* Narines, aisselles, aines
Persiste dans l’environnement hospitalier
Résistant aux antifongiques
Présent au Québec depuis 2012

23
Q

Which fungus is this:
Niche écologique peu connue
* Origine environnementale
* Virulence similaire à C. albicans
* Colonise la peau
* Narines, aisselles, aines
* Persiste dans l’environnement hospitalier
* Résistant aux antifongiques
* Émergence globale
* Présent au Québec depuis 2012

A

Candida auris

24
Q

Name the two primary fungus and not opportunistic

A

Endémiques
Dermatophytes

25
Q

Which ones here cause pneumonia:
Candida Cryptococcus Aspergillus Mucorales Endémiques Pneumocystis Dermatophytes

A

Cryptococcus,
Aspergillus,
Endémiques,
Pneumocystis

26
Q

Which ones have VIH/SIDE infection as a risk factor:
Candida Cryptococcus Aspergillus Mucorales Endémiques Pneumocystis Dermatophytes

A

Candida
Cryptococcus
Endémiques
Pneumocystis

27
Q

Which ones has interhuman transmission:
Candida Cryptococcus Aspergillus Mucorales Endémiques Pneumocystis Dermatophytes

A

Candida (rare)
Pneumocystis
Dermatophytes

28
Q

This causes Tinea: pied d’athlete:

Candida Cryptococcus Dermatophytes Aspergillus Mucorales Endémiques Pneumocystis

A

Dermatophytes

29
Q

Common with Vulvovaginite

Candida Cryptococcus Aspergillus Mucorales Endémiques Pneumocystis Dermatophytes

A

Candida

30
Q

Corticostéroïdes are a risk factor:
Candida Cryptococcus Aspergillus Mucorales Endémiques Pneumocystis Dermatophytes

A

Candida
Cryptococcus
Aspergillus
Pneumocystis

MMD1047 (23 decks)

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