Fundamentals of Infertility Flashcards
1
Q
classic definition of infertility
A
1 year of attempted pregnancy, normal repro age with regular monthly cycles
2
Q
Normal chance of becoming pregnant in 6 months
A
20% chance/month
3
Q
Which days of menstrual cycle + intercourse = likely pregnancy?
A
Day of ovulation and 2 days before
4
Q
hirusitism and oligomennorhea
A
PCOS
5
Q
clomiphene
A
acts by blocking estrogen negative feedback at the estrogen receptor in the hypothalamus –> increased GnRH secretion from the hypothalamus that stimulates FSH secretion from the pituitary
6
Q
letrozole
A
aromatase inhibitor
block production of estrogen so that negative feedback is reduced (increases GnRH secretion from hypothalamus –> stimulates FSH secretion from pituitary)
7
Q
effects of obesity on fertility
A
- inc rate of miscarriage
- inc rate of ovulatory dysfunction
- dec responsiveness to clomiphene
- dec preg rate even w/ regulator ovulatory cycles
