Functional Organisation of the Nervous System Flashcards

1
Q

What are the 4 main features of cortical organisation

A

Regional specialization
Distributed networks
Functional asymmetry
Maps over the cortical surface

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2
Q

Describe the regional specialization in the cortex

What regional function is associated with

  • frontal
  • prefrontal
  • parietal
  • occipital
  • temporal
A

Principle processing of different functions
Areas feed into each other and interact

Frontal, motor cortex
Prefrontal, cognition
Parietal, sensory cortex
Occipital, visual cortex
Temporal, hearing
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3
Q

Describe how the specialized regions of the brain contribute to vision

What are these regions associated with

A

Visual activity activates the occipital region

Activates dorsal and ventral regions

Dorsal
-Spatial processing

Ventral
-Object processing

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4
Q

Describe how the specialized regions of the brain contribute to decision making

What regions of the brain are activated

What happens if you can’t use one of these regions

A

Decision making => activates frontal and parietal regions

Without it

  • Impatient
  • Impulsive
  • Difficulty making decisions
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5
Q

Describe the functional asymmetry found in the brain in relation to language

What lobes are involved
Describe the pathway for processing

What happens if the corpus callosum is cut

A

Language => temporal lobe

Reading in left visual field => processed in R side of the brain
Signal passes through corpus callous => L brain in word form area

If corpus callosum cut, can see words, can’t read them

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6
Q

Descibe the cortical maps found in the motor and sensory regions of the frontal and parietal lobes

Describe the distribution of each body part to each section of the cortical map

A

Alongside central sulcus

As you move down the central sulcus laterally, the brain receives impulses from body parts from the bottom up

The most important motor/sensory functions get larger proportions of the cortex

L brain controls muscles on R side and vice versa

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7
Q

What is the main function of the cortex

A

Takes info about

  • metabolism
  • physiology
  • behaviour

Takes this data and makes decisions based on this

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8
Q

Describe the 2 properties about local motor circuit functions

What are the 3 types and what do they do

How do these local motor circuits relate to the cortex

A

Control behaviour
Can act autonomously

Spinal cord and hindbrain
-Sensory input => motor output

Midbrain
-Integrated startle response and eye movement

Monitored and modified via long connections to and from the cortex

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9
Q

Describe the organisation of the spinal cord and the structures that allow for localized motor circuit function

A

Sensory info integrated => motor input
Enlargement of lumbar and cervical spinal cord
-Larger ventral horn => motor info transmitted

Sensory
-pressure, touch, pain info

Central pattern generator
-gives integrated limb movement

Motor
-coordinated flexion and extension

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10
Q

Where is the hindbrain

What cranial nerves are associated with this region

What functions are associated with this region

A

Medulla + pons

Cranial V- XII

Local circuits used in muscle control and sensation
Hearing

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11
Q

What cranial nerves are associated with the midbrain

What functions are associated with this region

A

Cranial nerves III-IV

Motor eye movements driven by both visual and auditory cues (startle reflex in sup and inf colliculus)

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12
Q

How is metabolic regulation controlled in the brain

A

ANS and endocrine inputs integrated by the hypothalamus

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13
Q

What are the 6 main functions of the hypothalamus

A
Circadian rhythms
Energy metabolism
Reproductive behavior
Body temp
Aggression/defensive behavior
Blood pressure/electrolytes

Basically integrates what your body and brain does

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14
Q

Where is the hypothalamus in the brain

A

In ventral diencephalon

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15
Q

What is the importance of the thalamus and how does it relate to the cortex

A

Reciprocal connections with every part of the cortex

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16
Q

Where is the thalamus in the brain

A

In dorsal diencephalon

17
Q

What structure in the brain is associated with the thalamus and reward

How does it function
What pathology is associated with the lack of a response

A

Basal ganglia
-found deep in the cerebral hemispheres

Modulates response when there is a memory of a reward

Parkinsons
-response not modulated => hard to start/stop moving

18
Q

What structure in the brain is associated with the thalamus and error calculation

A

Cerebellum
-under occipital lobe

Constantly calculating errors and adjusting fine movement

19
Q

How does sensory input relate to the thalamus

A

Any sensory input => thalamus => cortex

20
Q

What are the 4 key features of the learning and output capacity of the cerebral cortex

Where is the output pattern distributed to

What pathology is associated with a damaged thalamus

A

Assemble large tasks
Compare to stored patterns
Predict and decide on output pattern
Distribute output pattern

Corticospinal
Corticobulbar (hindbrain)
BYPASSES THALAMUS

Locked in syndrome

21
Q

Describe the 3 axis of the head and brain

A

Ventral/ant <=> Dorsal/post (front and back of neck)

Rostral <=> Caudal
(frontal lobe <=> spinal cord)

Ventral/inf <=> Dorsal/sup
(mouth <=> top of head)

22
Q

What is the basic structure of the CNS

A

Tube with a continuous inner lumen filled with CSF

23
Q

Describe the development of the regions of the brain along the rostrocaudal axis

A

Forebrain, midbrain, hindbrain, spinal cord

Forebrain => Diencephalon at the bottom and telencephalon at the top

24
Q

Describe the formation of the CNS tube

A

Ectoderm folds => neural tube closes => defines dorsal midline

Dorsal midline, origin of neural crest => PNS formed from migration of the neural crest

Major central subdivisions map to neutral rostrocaudal axis

25
Q

How are the ventricles formed

A

Neural tube expands => ventricles to form CSF

26
Q

Name 3 neurulation defects and why they occur

A

Anencephaly
-Telencephaly formation fails

Craniorachischisis
-Open spina cord

Spina bifida
-Failure of neural tube closure