Brainstem and Subcortical areas Flashcards

1
Q

What are the subdivisions of the brainstem

A

Midbrain
Pons
Medulla oblongata (projects through foramen magnum)

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2
Q

What cranial nerve roots can be found at the brainstem

Which cranial nuclei are on the floor of the 4th ventricle

A

III-XII (I and II under cerebrum base)

V-VIII nuclei on the floor of the 4th centricle

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3
Q

Describe the transverse section of the midbrain at the level of the superior colliculi

A
From dorsal to ventral
Sup colliculli
Oculomotor nuclei
Red nucleus
Substantia nigra
Crus cerebri
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4
Q

Why is the brainstem important

What happens if there’s damage here

A

Contains groups of monoaminergic nuclei involved in movement control, consciousness, HR and breathing
Damage here => coma/death

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5
Q

What is the function of the thalamus
What does it regulate
What happens if theres damage here

A

All sensory info passes through here except smell
Dampens, filters info that goes to the cerebrum

Regulates

  • consciousness
  • sleep
  • awareness
  • attention
  • arousal

Sleep problems, fatal insomia, forms of epilepsy

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6
Q

Where is the thalamus
What structure does it flank
What anatomically redundant structure is occasionally found here?

What structure is found inferior to the thalamus

A

Above the midbrain
2 halves of thalamus flank 3rd ventricle
-can be fused across the midline by an interthalamic adhesion (no function)

Hypothalamus inferior to thalamus

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7
Q

Describe the function of the basal nuclei

A

Involved in movement production
Cognitive reward behavioural reinforcement
-dopamine surge precedes thoughts/actions of high motivational value

Affects the modulation of what sensory info reaches the cortex from the thalamus

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8
Q

Name the structures found in the basal nuclei

A

Caudate nucleus flanks both lateral ventricles
Lentiform nucleus flanks internal capsule which flanks both lobes of thalamus

3rd ventricle under lateral ventricles

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9
Q

Describe the structure of the lentiform nucleus

A

From lateral => medial
Putamen
Globus pallidus externus
Globus pallidus internus

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10
Q

What 2 structures are part of the striatum

What structure is confusingly not part of the striatum

A

Caudate nucleus and putamen

Lentiform nucleus is not part of the dorsal striatum

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11
Q

Describe the relationships between the cortex and the basal nuclei
Why is the relationship important

A

Cortex sends excitatory impulses => striatum + substancia nigra pars compacta

Striatum sends inhibitory messages to both globus pallidi

Both globus pallidi send inhibitory messages to the thalamus

Thalamus sends excitatory impulses => cortex

Substancia nigra pars compacta moderates striatum activity

Finely balanced control of excitatory and inhibitory messages => motor control

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12
Q

Describe and explain the relative cross sectional thicknesses of the areas of the spinal cord

A

Cervical and lumbar are the thickest

-contain all motor neurones for upper and lower limbs

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13
Q

Describe the relative numbers of root ganglions

  • dorsal
  • ventral
A

DRG => several

VRG => 3-4

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14
Q

Describe the relative lengths of the nerves from the SC to the DRG

  • cervical
  • thoracic
  • lumbar
A

Cervical
-1-2

Thoracic
-2-4

Lumbar
-5-25

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15
Q

What is the conus medullaris

What is the filum terminale

A

Conus medullaris
-tapered lower end of the SC

Filum terminale
-pious tissue from conus medullaris => bottom of the vertebrae

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16
Q

Describe the relative lengths of the vertebral column and spinal cord

A

Spinal cord
-40-50

Vertebral column
-70

17
Q

Describe the relationship between the SC and the cauda equina

Where would you do a lumbar puncture

A

VC longer than SC

Cauda equina comes off L1 downwards

Between

  • L3/4
  • L4/5
  • L5/S1 so SC not hit
18
Q

Describe anterograde degeneration

A

Axon damaged

Region past damage dies as it can no longer contact the cell body

19
Q

Describe cell body ablation

A

Cell body damaged

Whole neurone dies as cell body can’t send impulses to the rest of the ell

20
Q

What happens when axons die

A

Myelin sheath degenerates and disappears