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First Aid Renal > Fluids > Flashcards

Fluids Flashcards

1
Q

ECF fraction

A

1/3 TBW

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2
Q

ICF fraction

A

2/3 TBW

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3
Q

Plasma Volume fraction

A

1/4 of ECF

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4
Q

Interstitial Volume fraction

A

3/4 of ECF

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5
Q

Radiolabeled Albumin

A

Measures plasma volume

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6
Q

Inulin

A

Measures Extracellular Volume

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7
Q

Loss of Glomerular filtration barrier charge

A

Nephrotic syndrome resulting in albuminuria, hypoproteinemia, generalized edema, and hyperlipidemia

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8
Q

Glomerular FIltration Barrier Components

A

Fenestrated capillaries, Basement membrane with heparin sulfate (to give negative charge), Podocytes

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9
Q

Volume of plasma from which the substance is completely cleared per unit time

A

Renal Clearance

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10
Q

Clearance of X < GFR

A

Net reabsorption

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11
Q

Clearance of X > GFR

A

Net secretion

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12
Q

Clearance of X = GFR

A

no net secretion of reabsorption

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13
Q

Inulin Clearance

A

Used to calculate GFR; freely filtered. Neither reabsorbed nor secreted; usually is 100mL/min

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14
Q

Creatinine Clearance

A

Used to estimate GFR but slightly overestimates it since renal tubules moderately secrete creatinine

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15
Q

Para-aminohippuric acid (PAH) Clearance

A

Used to calculate Effective RPF; both filtered and actively secreted in the proximal tubule

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16
Q

ERPF

A

effective renal plasma flow; underestimates true RPF by ~10%

17
Q

Dilate Afferent Arterioles

A

Prostaglandins (increases RPF and GFR thus FF remains the same)

18
Q

Constricts Efferent Arteriole

A

Ang II (decreased RPF, increases GFR, so FF increases)

19
Q

NSAIDs

A

prevents dilation of afferent arterioles

20
Q

ACE-Is

A

Prevent constriction of efferent arterioles

21
Q

Afferent arteriole constriction

A

Decreases RPF and GFR; no change in FF

22
Q

Efferent arteriole constriction

A

Decreases RPF and Increases GFR; increases FF

23
Q

Increase Plasma Protein Concentration

A

Decreases GFR; decreases FF

24
Q

Decrease Plasma Protein Concentration

A

Increases GFR and Increases FF

25
Q

Constriction of Ureter

A

decreases GFR and decreases FF

26
Q

Glucose and normal plasma level

A

Completely reabsorbed in PT by Na/Glucose cotransport.

27
Q

Threshold of glucose; start glucosuria

A

~200mg/dL

28
Q

Tm of glucose; all transporters are fully saturated

A

~375mg/dL

29
Q

Pregnancy on Amino acids and Glucose

A

decrease reabsorption of glucose and AA in PT; glucosuria and aminoaciduria

30
Q

Auto. recessive; deficiency of neutral AA transporters in prox renal tubules and enterocytes

A

Hartnup Disease

31
Q

Neutral aminoaciduria; pellagra-like symptoms Tx

A

High protein diet and nicotinic acid (tx for hartnup disease)

First Aid Renal (14 decks)

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