Fluid Imbalances Flashcards

1
Q

Percentage of adult body weight from water? Infants?

A

50-60%

70%

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2
Q

What organ contains the most water? Next one?

A

Lungs: 83%

muscles and kidneys: 79%

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3
Q

More fluid in veins or arteries?

A

veins

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4
Q

Thirst mechanism is controlled by

A

osmoreceptors in hypothalamus

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5
Q

How do the osmoreceptors work in the thirst mechanism?

A

they react to increase in blood osmotic pressure

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6
Q

Hormones that control fluid retention?

A

Antidiuretic hormone

Aldosterone

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7
Q

How does ADH work?

A

It controls fluid output through urine. It increases reabsorption of water from kidney tubules into the blood.

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8
Q

How does aldosterone work?

A

increases reabsorption of sodium and water from kidney tubules into the blood.

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9
Q

When is atrial natriuretic peptide produced?

A

in response to high atrial BP

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10
Q

What does ANP do?

A

reduces reabsorption of sodium and water
promotes sodium loss in urine
reduces blood volume
reduces BP

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11
Q

Types of capillaries: continuous has what types of clefts?
fenestrated?
discontinuous?

A

intercellular
Intracellular
Intercelullar

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12
Q

Where are continuous capillaries normally found?

A

fat, muscle, nervous system, skin

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13
Q

Where are fenestrated capillaries normally found?

A

intestinal villi, endocrine glands, kidney glomeruli

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14
Q

Where are discontinuous capillaries normally found?

A

liver, bone marrow, spleen

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15
Q

Movement through the semi-permeable membrane is dependent on what two pressures?

A

hydrostatic and osmotic

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16
Q

What is hydrostatic pressure dependent on?

A

by pressure of fluid or filtration

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17
Q

What is osmotic pressure dependent on?

A

solute content

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18
Q

What are two major contributors to osmostic pressure?

A

sodium and albumin

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19
Q

In filtration fluid moves through a filter from….

A

higher to lower pressure

20
Q

In osmosis fluid moves through a filter from….

A

lower to higher pressure

21
Q

What does Starling’s Law say?

A

amount of fluid moved across a capillary wall is proportional to the net filtration pressure

22
Q

What is Starling’s Law a combination of?

A

hydrostatic and osmotic pressure

23
Q

What are four Starling’s forces?

A

hydrostatic pressure in capillary and interstitium

osmotic pressure in capillary and interstitium

24
Q

What forces in Starling’s Law are highest?

A

hydrostatic and osmotic in the capillaries

25
What pressure is higher in the arteriolar capillary vs the venule? How would that affect movement of fluid? How does this movement affect BP?
hydrostatic from blood to interstitium decreases because of decreased blood volume
26
What pressure is higher in the venule vs arteriolar? How would that affect movement of fluid? How does this affect BP?
osmotic from interstitium to blood increases (becomes more concentrated)
27
Filtration happens more toward ... while absorption happens more towards...
arteriole | venule
28
Passive diffusion
high to low
29
Facilitated diffusion
high to low
30
Active transport
low to high with ATP
31
Isotonic solution water will move...
nowhere
32
Hypertonic solution, water will move...
from inside the cell to outside
33
Hypotonic solution, water will move...
from outside the cell to inside
34
Cause of edema could be due to loss of .... particularly...which results in ....plasma osmotic pressure and ...fluid return to the venous capillary.
plasma proteins albumin decreased less
35
Loss of albumin can be from
``` kidney disease severe burns hemorrhage malnutrition/malabsorption liver disease ```
36
Another cause of edema?
obstruction of lymphatic circulation
37
Another cause of edema?
increased capillary permeability usually from inflammation
38
During an inflammatory response, what happens to cause edema?
proteins leak out, there is increased osmotic pressure in ISF and retention of water
39
Widespread edema is caused by?
bacterial toxins or large burn wounds
40
Functional restrictions of edema?
ROM heart (impaired diastole) lung (reduced vital capacity) interferes with digestion or absorption
41
Pain as an effect of edema?
local pressure inserted on nerves headache stretching of capsule in organs
42
Some effects of edema on circulatory system?
impaired arterial circulation: ischemia due to tissue breakdown, necrosis, ulcers
43
Isotonic in terms of hydration Hypotonic in terms of hydration Hypertonic in terms of hydration
proportionate loss of water and electrolytes; loss of more electrolytes than water; loss of more water than electrolytes
44
Hypovolemia
depletion of vascular compartment; water moves from inside the cells to the vascular bed to maintain blood volume and BP so cells may malfunction; aka hypovalemic shock
45
Attempts to compensate for fluid loss
``` increase thirst increase HR constrict cutaneous BV sweating decreased produce less urine increase hemtocrit ```