Fluid and electrolytes Flashcards
T/F: Crystalloids contains proteins
false
Pros of crystalloids
no risk for viral transmission, anaphylaxis, alteration in coagulation profile
Crystalloids indication
Dehydration, fluid loss, electrolyte disturbance, promote urinary flow
others: acute liver failure, acute nephrosis, respiratory distress, burns, cardiopulmonary bypass, hypoproteinemia, DVT, shock
T/f: Crystalloids are used to expand plasma vol
false
Crystalloids examples
- NS: 0.9% sodium chloride (isotonic), 0.45% half normal (hypotonic)
-3.3% dextrose and 0.3% NS (isotonic) - lact ringers sol (isotonic)
-dextrose 5% in water (isotonic)
-D5W and o.45% NS (hypertonic)
-3% sodium chloride (hypertonic saline)
Crystalloids adverse effects
-Edema
-diluted plasma protein = decreased colloid oncotic pressure
Adverse effects of crystalloid from long term use
alkalosis, acidosis
Colloids examples
-albumin 5% and 25% (from human donors)
-dextran 40 or 70 (available in sodium chloride and 5% dextrose)
-hetastarch
Colloids adverse effects
altered coagulation & bleeding
Cons of colloids
no clotting factors or oxygen carrying capacity; bleeding risk
Pros of dextran therapy
rare anaphylaxis or kidney failure
Pros of Blood products
only one carrying oxygen, increase tissue oxygenation, increase plasma vol
Cons of blood products
most expensive and least available, risk of reactions to fluid; require human donors
Type of blood products
-cryoprecipitate and plasma protein factors
-Fresh frozen plasma
-Packed RBC
-Whole blood
cryoprecipitate and plasma protein factors indication
management of acute bleeding (> 50% slow blood loss or 20% acutely)
Fresh frozen plasma indication
increasing clotting factors for pts with deficiency
Packed RBC indications
increase oxygen carrying capacity in anemia, hemoglobin deficits, < 25% total blood vol loss
Whole blood indication
> 25% loss of total blood vol
Blood products adverse effects
incompatibility with recipients immune system, transfusion reaction, anaphylaxis, pathogen transmission (hepatitis, HIV)