Fitz9. Ch15: Epidermal and Dermal adhesion Flashcards

1
Q

Bullous impetigo
SSSS
Inherited ichthyosis with netherton

Pemphigus foliaceous

Due to what type of desmosomal cadherin

A

desmoglein 1

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2
Q

SCC

Pemphigus vulgaris
Paraneoplastic pemphigus

Due to what desmosomal cadherin ?

A

Desmoglein 3

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3
Q

Hypotrichosis (Autosomal recessive) and monilethrix is due to what desmosomal cadherin?

A

Desmoglein 4

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4
Q

IgA pemphigus (subcorneal pustular dermatosis) due to what desmocollin?

A

Desmocollin 1

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5
Q

Pemphigus vegetans

A

Desmocollin 3

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6
Q

Paraneoplastic pemphigus

Carvajal (left)

A

Desmoplakin I/II

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7
Q

Naxos (right)

A

Plakoglobin

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8
Q

Skin fragility and ectodermal dysplasia

A

Plakophilin 1

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9
Q

Paraneoplastic pemphigus

(2) plakins

A

Envoplakin

Periplakin

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10
Q

Hypotrichosis simplex - autosomal dominant

A

Corneodesmosin

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11
Q

Components of the basement membrane

A
Collagen IV
Laminins 
Nidogens
Heparan sulfate 
Fibulins
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12
Q

Cutis Laxa

A

Fibulin 4 and fibulin 5

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13
Q

BP230 is_____ while

BP180 is ____

A

BP 230: Epidermolysis bullosa simplex

BP180: bullous pemphigoid

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14
Q

Collagen 17

A

Junctional epidermolysis bullosa

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15
Q

Pyloric atresia with

  1. Epidermolysis bullosa is ____ while
  2. Junctional Epidermolysis bullosa ____
A

Pyloric atresia with

  1. Epidermolysis bullosa is PLECTIN
  2. Junctional Epidermolysis bullosa INTEGRIN alpha 6 beta 4
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16
Q

Interstitial lung disease
Nephrotic Syndrome
Epidermolysis bullosa

A

INTEGRIN alpha 3 beta 1

17
Q

Kindler Syndrome

A

KINDLIN 1

18
Q

Acquired Epidermolysis bullosa
EBA,
Bullous SLE

Is by what collagen?

A

Collagen 7

19
Q

Dystrophic Epidermolysis bullosa

A

COL7A1