Fitz9. Ch10: Immunologic Structure Of Skin

Question 1

Innate vs. adaptive immunity

Answer 1

Innate has rapid onset,
Capacity to discriminate between danger and no danger
Lack of memory

Question 2

What are the pattern recognition receptors? (4)

Answer 2

1. Toll-like receptors
2. Nucleotide-binding oligomerizarion domain like receptors
3. Retinoic acid inducible gene-like receptors
   4: c-type lectin receptors

Question 3

Cellular constituents of the adaptive immune system?

Answer 3

Dendritic: langerhan cells, cd141 DC, dermal DC, inflam DC

T-lymphocytes: naive, memory

Question 4

TLR responsible for imiquimod and is effective for genita warts, actinic keratosis, basal cell carcinomas

Answer 4

TLR7

Question 5

Type of dendritic cell whose main function is for cross presentation

Answer 5

cd141 DC

Question 6

Allergic contact dermatitis is

TH___, Innate lymphoid cell____ and ____

Answer 6

ACD is Th1, ILC 1 and Tbet

Question 7

Atopic dermatitis is

Th___ ILC____ And _____

Answer 7

AD is Th2, ILC 2 and GATA3

Question 8

Psoriasis is

Th___ ILC___ and ___

Answer 8

Psoriasis is th17, ILC3 and ROR