FINALS - ANEMIA P1 Flashcards

1
Q

According to WHO ______ is a condition in which number of RBC or Hgb concentration is lower than the normal.

A

ANEMIA

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2
Q

is a manifestation of a certain disease associated with a
decrease in the red blood cell, decrease in hematocrit and
a decrease in hemoglobin.

A

anemia

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3
Q

is anemia a primary disease?

A

no

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4
Q

Anaimia

an =
haima =

A

an = lack
haima = blood

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5
Q

Functional def of anemia

A

decrease in the oxygen carrying capacity of the blood.

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6
Q

Operational definition of anemia

A

reduction from the baseline value for the total
number of RBCs, amount of circulating hemoglobin,
and RBC mass for a particular patient.

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7
Q

Conventional definition of rbc

A

decrease in RBCs, Hb and Hct below the previously established reference values for healthy individuals of the same age, gender, and race and under similar environmental conditions.

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8
Q

Clinical Findings of Anemia

A
  1. History
  2. Physical examination
  3. Signs and symptoms
  4. Laboratory procedures
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9
Q

most common symptoms of anemia

A

 Shortness of breath
 Fatique
 Weakness

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10
Q

clinical findings that are not covered by medtechs

A
  1. History
  2. Physical examination
  3. Signs and symptoms
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11
Q

Laboratory procedures for anemia

A

CBC, iron studies, hemoglobin electrophoresis

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12
Q

backbone of anemia

A

iron studies

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13
Q

In History of Patient, we check for the _

A

 Diet
 Bleeding history
 Drug ingestion
 Occupation
 Exposure to chemicals
 Travel
 Previous medication
 Ethnic group
 Family history of disease
 Hobbies
 Neurologic symptoms

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14
Q

how many iron we lose every day

A

1mg of iron per day

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15
Q

In physical examination, we check for the ___

A

 Skin: pallor
 Eyes (hemorrhage)
 Mouth (mucosal bleeding)
 Sternal tenderness
 Lymphadenopathy
 Cardiac murmurs
 Splenomegaly- enlargement of spleen
 Hepatomegaly- enlargement of liver
 Vital signs-

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16
Q

pallor in skin means

A

decrease in oxyhemoglobin

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17
Q

jaundice is an indicator of___

A

hemolysis

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18
Q

a skin symptoms which means there’s a breakage of capillaries

A

petechia/petique

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19
Q

vital signs includes

A

temperature, blood pressure, heart rate

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20
Q

General causes of Anemia

A
  1. Decreased red blood cell production (BONE MARROW FAILURE)
  2. Increased red blood cell destruction (extrinsic or intrinsic)
  3. Blood loss (acute or chronic)
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21
Q

Anemia due to decreased production of RBC

A
  1. Iron Deficiency Anemia, IDA
  2. Anemia due to Chronic Inflammation/ chronic disease, ACI or ACD
  3. Sideroblastic Anemia (blockage in heme synthesis)
  4. Megaloblastic Anemia (deficiency in vitamin B12)
  5. Aplastic Anemia (sa bone marrow)
  6. Thalassemia (walang alpha or beta)
  7. Anemia due to Chronic Renal Failure
  8. Anemia due to Endocrine Disorder (cushing syndrome, addison’s disease)
  9. Anemia due to Marrow Infiltration (myelophthisic anemia)
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22
Q

(most common type and easiest to treat)

A

iron deficiency anemia, IDA

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23
Q

decrease production of WBC, RBC and platelets

A

Pancytopenia-

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24
Q

diseases under endocrine disorder

A

cushing syndrome, addison’s disease

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25
Q

example of anemia due to marrow infiltration

A

(myelophthisic anemia)

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26
Q

classification of Anemia due to increased destruction of RBC

A

A. Intracorpuscular Abnormality (Intrinsic)
B. Extracorpuscular Abnormality (Extrinsic)

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27
Q

Intracorpuscular Abnormality (Intrinsic)

has 2 classifications as well, what are they/

A

Membrane Defect (problem sa membrane ng RBC, sa lipid, carbohydrate and protein)

Enzyme deficiency

Paroxysmal Nocturnal Hemoglobinuria (PNH)

Globin abnormality

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28
Q

Extracorpuscular Abnormality (Extrinsic)

has 2 classifications as well, what are they?

A
  1. Mechanical
  2. Infection
  3. Chemical and Physical Agents
  4. Antibody-mediated Anemia (AMA)
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29
Q

conditions under membrane defect (intrinsic)

A

a) hereditary spherocytosis
b) hereditary elliptocytosis
c) hereditary pyropoikilocytosis
d) hereditary stomatocytosis
e) hereditary acanthocytosis
f) hereditary Rh null disease

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30
Q

conditions under enzyme deficiency (intrinsic)

A

a) G6PD deficiency
b) Pyruvate kinase deficiency
c) Porphyria

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31
Q

conditions under the globin abnormality (intrinsic)

A

Hemoglobinopathies (Hb SS, CC, SC)
 Sgal, Cgal, Egal

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32
Q

conditions under the mechanical (extrinsic)

A

a) Microangiopathic hemolytic anemia (MAHA)
b) Traumatic cardiac hemolytic anemia

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33
Q

if there’s MAHA, other conditions are can be associated as well such as

A

 thrombotic thrombocytopenic purpura
(TTP)
 hemolytic uremic syndrome (HUS)
 Disseminated intravascular coagulation
(DIC)

additional
 Hemolysis, Elevated Liver enzymes and
Low Platelets count (HELLP)- seen in
pregnant patient

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34
Q

a mechanical extrinsic condition seen in pregnant women

A

Hemolysis, Elevated Liver enzymes and
Low Platelets count (HELLP)

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35
Q

conditions associated in INFECTION - EXTRINSIC

A

hemolytic anemia
- malaria
- babesia
- bartonella
- ehrlicia

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36
Q

causes of chemical and physical agents under the EXTRINSIC factors

A

caused by drugs, toxins, and burns

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37
Q

condition associated to antibody-mediated anemia (ANEMIA) - EXTRINSIC

A

acquired hemolytic anemia

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38
Q

examples of anemia due to blood loss

A

acute post hemorrhagic anemia
chronic post hemorrhagic anemia

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39
Q

laboratory test for anemia

A
  1. CBC (Manual: Hgb, Hct, RBC, WBC, DC)
  2. Reticulocyte count (checking of electrophoretic activity ng bone marrow)
  3. Peripheral smear (for morphology ng cells kung abnormal or normal cells)
  4. Bone marrow examination
  5. Iron studies (ang backbone which includes serum, iron, ferritin, total iron binding capacity/TIBC)
  6. Blood Chemistry (KFT/kidney function test, LFT/liver function test)
  7. Urinalysis
  8. Fecalysis
  9. Hematological special test procedures (Hgb electrophoresis)
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40
Q

iron studies is the backbone of anemia which includes the study of ___

A

serum, iron,
ferritin, total iron binding capacity/TIBC

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41
Q

a laboratory test that is for morphology ng cells kung abnormal or normal cells

A

peripheral smear

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42
Q

checking of electrophoetic activity ng
bone marrow

A

reticulocyte

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43
Q

Blood Chemistry done in anemia such as __

A

(KFT/kidney function test, LFT/liver
function test)

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44
Q

Morphological Classification of Anemia

A

1 Microcytic hypochromic anemia (found in SIGA)
2. Macrocytic normochromic anemia
3. Normocytic normochromic anemia

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45
Q

best anemia example of normocytic normochromic anemia

A

aplastic anemia

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46
Q

small rbc and low concentration of hgb

A

microcytic hypochromic anemia

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47
Q

big rbc and normal concentration of anemia

A

macrocytic normochromic anemia

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48
Q

based on the morphological classification of anemia (mcv based)

what is under the microcytic anemia

A

SIGA

Sideroblastic anemia
iron deficiency
anemia, chronic diseases
globin deficiency (thalassemia)

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49
Q

based on the morphological classification of anemia (mcv based)

what is under the macrocytic anemia

A

Non megaloblastic anemia
megaloblastic anemia

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50
Q

based on the morphological classification of anemia (mcv based)

what is under the normocytic anemia

A

in increased retics:
hemolytic anemia

in normal or low retics:
aplastic anemia
hypercellular (myeloma, myelofibrosis, 1st refractory anemia)
normal cellular (neoplasm, uremia)

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51
Q

Non megaloblastic anemia has a disease under called

A

chronic liver disease

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52
Q

megaloblastic anemia has a disease under called

A

vitamin b12 deficiency
folic acid deficiency
neither * malignant growth

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53
Q

hemolytic anemia has 2 factors involved

A

intrinsic or extrinsic

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54
Q

intrinsic factors of hemolytic anemia are

A

membrane
enzyme
hemoglobin
PNH

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55
Q

EXTRINSIC factors of hemolytic anemia are

A

antibody mediated
infection (malaria)
chemical and physical agents (drugs, toxins, burns)
mechanical (MAHA, TTP, DIC, HUS)
- cardiac valve prosthesis
- march hemoglobinuria

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56
Q

microcytic hypochromic has decrease of ___

A

all erythrocyte indices: mcv, mchc, mch

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57
Q

microcytic hypochromic is found in what conditions

A

thalassemia and severe iron deficiency anemia

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58
Q

it determine the different type of anemia

A

rbc indices : mcv, mchc, mch

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59
Q

microcytic hypchromic is found in

A

SIGA

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60
Q

the most common type of anemia

A

iron deficiency anemia

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61
Q

easiest anemia to treat

A

IRON DEFICIENCY ANEMIA

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62
Q

what are the causes of IDA

A
  1. inadequate intake of iron
  2. Increased need of iron
  3. Chronic blood loss
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63
Q

how many mg of iron is lost everyday

A

1 mg

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64
Q

conditions that will increased the need of iron in Iron deficiency anemia

A

infancy, childhood, adolescence, and pregnancy

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65
Q

chronic blood loss in IDA are caused by

A
  1. heavy menstrual bleeding
  2. GI bleeding from ulcers or tumors.
  3. urinary trach with kidney stones
  4. Iatrogenic cause
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66
Q

In IDA, the 3 cause which is the chronic blood loss, what is an example of Iatrogenic cause

A

ikaw at ikaw ang nagvovolunteer for sample

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67
Q

In pathogenesis of Iron deficiency anemia

what are the 3 stages

A
  1. Stage I- Iron Depletion
  2. Stage II – Exhaustion of the storage pool of iron
  3. Stage III – Frank Anemia
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68
Q

In stage 1 iron deficiency

Hgb =
serum iron =
total binding capacity =
ferritin =

A

Hgb = normal
serum iron = normal
total binding capacity = normal
ferritin = low

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69
Q

what is the one affected in stage 1 Iro depletion of IDA

A

Ferritin - the value is low

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70
Q

will measure the circulating iron that is bound to transferring

A

serum iron

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71
Q

measure the capacity of
iron to bind transferrin

A

Total Iron Binding Capacity

72
Q

protein that are used for storge of iron

A

ferritin

73
Q

Stage II of IDA– Exhaustion of the storage pool of iron

 Normal =
 Decreased =
 Increased =
 Decreased =
 RBC development still normal

A

 Normal = Hb
 Decreased = serum iron
 Increased = TIBC
 Decreased = ferritin
 RBC development still normal

74
Q

Stage III of IDA– Frank Anemia

 Decreased =
 Decreased=
 Decreased =
 Increased =

A

 Decreased = Hb
 Decreased= iron
 Decreased = ferritin
 Increased = TIBC

75
Q

Blood Features of IDA

A

 ↓ to normal retic
 ↓ serum iron
 ↓ serum ferritin
 ↑ total iron-binding capacity (TIBC)
 Microcytic hypochromic type of Anemia
 Anisocytosis (size of RBC) /Poikilocytosis (shape of RBC)
 Decrease in OFI (osmotic fragility test)

76
Q

supplement or treatment for IDA

A

avoid puyat and eat nutritious food
FERROUS sulfate, plus Vitamin C

77
Q

purpose of vit c with ferrous sulfate

A

increase absorbtion

78
Q

CATEGORIES OF LAB DIAGNOSIS FOR ANEMIA

screening

A

cbc and rbc indices

79
Q

CATEGORIES OF LAB DIAGNOSIS FOR ANEMIA

specialize

A

Hb electrophoresis

—–Look for underlying cause
— treatment ferrous sulfate and vt x

80
Q

CATEGORIES OF LAB DIAGNOSIS FOR ANEMIA

diagnostic

A

Backbones of anemia
— Iron studies

81
Q

SEVERE TYPE OF IRON DEFICIENCY has a presence of

A

koilonychia and Smooth tongue adn PICA

82
Q

, a condition also referred to as
“spoon-shaped nails,” is associated with iron
deficiency in which the fingernails are thin, brittle,
and concave with raised edges.

A

Koilonychia

83
Q

Condition where there’s a craving for uncertain food.

Ex: dirt, clay, chalk - non certain food

A

PICA

84
Q

_ can result in a painless, smooth,
shiny, and reddened tongue

A

Iron deficiency - smooth tongue

85
Q

Mahilig ngumata ng yelo

A

PAGOPHAGIA

86
Q

morphology or appearances we can see in a blood film of a patient with IDA

A

pencil cells, target
cells, teardrops, and rare fragments.

87
Q

Early iron deficiency may be normocytic with no significant morphologic changes.

true or false

A

true

88
Q

develop when the incorporation of iron into heme is blocked.

A

SIDEROBLASTIC ANEMIA

89
Q

Blocked during heme synthesis

A

SIDEROBLASTIC ANEMIA

90
Q

Diseases that interfere with the production of adequate amounts of protoporphyrin ring

A

SIDEROBLASTIC ANEMIA

91
Q

Primary caused of sideroblastic anemia is ___

A

genetic

92
Q

secondary caused of sideroblastic anemia is ___

A

o Certain therapeutic drugs
o Chronic transfusion (Aplastic)
o Alcoholism and food fads
o Use of iron utensils & iron in water

93
Q

Diagnostic lab finding (hallmark) of sideroblastic anemia

A

is ringed sideroblasts in the bone marrow

Pappenheimer bodies in peripheral blood

94
Q

the excess iron in sideroblastic anemia shows as a blue dots around the cell and can be seen only using a stain

A

Perl’s Prussian blue

95
Q

lead poisoning is another type of a condition wherein there’s problem with __

A

heme sysnthesis

96
Q

lead interferes with ___ in the mitochondria

A

iron storage

97
Q

lead damages the activity of the enzyme used for synthesis (__)

A

basophilic stippling

98
Q

all under heme synthesis

A

sidroblastica anemia
lead poisoning
porphyria

99
Q

rare diseased caused by acumulation of porphyrin in developing rbc

A

porphyria

100
Q

characterized by dermal photosensitivity and raused caused by the sun

A

porphyria

101
Q

the original werewolf is the one with

A

erythropoietic porphyria

102
Q

ANEMIA DUE TO CHRONIC INFLAMMATION

anemia associated with systemic diseases:

A

o arthritis
o tuberculosis
o HIV
o malignancies
- leukemia, lymphoma, myeloma

103
Q

second most common type of anemia

A

ACI or ACD

104
Q

Lab features of ACI or ACD

A

o Decreased= TIBC
o Mild anemia – HB = 7-11 g/dL
o Increased= WBC (because there’s inflammation)

105
Q

inherited disorders caused by genetic alterations that reduce
or preclude the synthesis of the globin chains of hemoglobin tetramer.

A

THALASSEMIA

106
Q

anemia that is Maaaring wala ang alpha or beta, or baka mahina o kuang
yung alpha or beta

A

THALASSEMIA

107
Q

For as to have Hb normal= what are the globins

A

2 pairs alpha & 2 pairs beta

108
Q

THALASSEMIA predominant in ____

A

Mediterranean, African and Asian ancestry.

109
Q

THALASSEMIA First described by ___

A

COOLEY and LEE in 1925

110
Q

Types of Thalassemia

A
  1. Beta (β) Thalassemia
  2. Alpha (α) Thalassemia
  3. Hereditary Persistence of Hb F (HPHF)
  4. Hemoglobin Lepore
  5. Hemoglobinopathy + Thalassemia
    a. Hemoglobin S- Thalassemia
    b. Hemoglobin C-Thalassemia
    c. Hemoglobin E-Thalassemia
111
Q

Sa thalassemia may ___ na nangyayari

A

hemolysis

112
Q

in thalassemia, all the lab test is normal except

A

reticulocyte count

113
Q

. Beta (β) Thalassemia

beta chain is on

A

chromosome 11

114
Q

Thalassemia minor

  • Hb= ___
A

10-13 mg/dL

115
Q

Thalassemia minor

Other names

A

Heterozygous
thalassemia

Cooley’s trait

116
Q

results when one of
the 2 genes that
produce beta globin
is defective

A

Thalassemia
minor

117
Q

a thalassemia that usually presents a
mild, asymptomatic
anemia

A

Thalassemia
minor

118
Q

Intermediate B
thalassemia -

Hb= ___

A

7 daw sa rec lec
9 mg/dL

119
Q

other name of intermediate b thalassemia

A

Thalassemia
Intermedia

120
Q

more severe
anemia than minor
B-thalassemia but
do not require
regular transfusion

A

Intermediate B
thalassemia

121
Q

occasional
transfusions but do
not require them on
a regular basis.

A

. Intermediate B
thalassemia

122
Q

Thalassemia
major

A

Homozygous
thalassemia

Cooley’s anemia

Mediterranean
anemia

Target cell anemia

123
Q

Thalassemia
major

  • Hb= ___
A

3-4 mg/dL

124
Q

-decrease or
complete lack of
beta globin
production

A

Thalassemia
major

125
Q

Thalassemia
major

Diagnosed between
___because
increase at
tumataas yung Hb A

A

6 months old to 2
yrs. old

126
Q

Characteristics of thalassemia major

A

death is due to circulating iron
overload (patient- mga bata) because
they are transfusion dependent

127
Q

patient appearance for thalassemia major

A

stunted growth (hindi
masyadong lumalaki)

frontal bossing
(protrude yung noo,
cheekbone is
highlighted/prominent,
gums and teeth are
protrude)

128
Q

Alpha (α) Thalassemia is coded on

A

chromosome 16

129
Q

. Alpha (α) Thalassemia

predominates

A

hemolysis

130
Q

an alpha thalasemia that there’s a deletion of one alpha globin leaving 3 functional a globin

A

silent carrier

131
Q

an alpha thalasemia that there’s a deletion of two alpha globin leaving 2 functional a globin

A

a thalassemia trait (homozygoud or heterozygous)

132
Q

an alpha thalasemia that there’s a only one gene producing gene producing chain

A

hemoglobin H disease

133
Q

results in the absence of all a chain synthesis

A

hydrops fetalis

134
Q

an alpha thalassemia that is incompatible to life

A

hydrops fetalis

135
Q

counterpart of the beta thalassemia major because
of the absence of all alpha chain

A

hydrops fetalis

136
Q

globin chains are important para sapag carry ng ___

A

O2

137
Q

appearance of hydrops fetalis patients

A

enlargement of spleen, liver and the baby are color
yellow

138
Q

thalassemia with increased levels of fetal hemoglobin

A

. Hereditary Persistence of Hb F (HPHF)

139
Q

partial or total suppression of beta and delta chains and HB F increased to compensate

A

Hereditary Persistence of Hb F (HPHF)

140
Q

a rare class of thalassemia caused by crossing over of beta and delta gene

A

Hemoglobin Lepore

141
Q

is a double heterozygous abnormality

A

Hemoglobin S- Thalassemia

142
Q

the abnormal genes for Hb S and thalassemia are coinherited

A

Hemoglobin S- Thalassemia

143
Q

β thalassemia with inherited Hb C

A

Hemoglobin C-Thalassemia

144
Q

minimal amount of or no Beta chain

A

Hemoglobin C-Thalassemia

145
Q

co-inherited of Hemoglobin E and β thalassemia that results
to a marked reduction of β chain production.

A

Hemoglobin E-Thalassemia

146
Q

a hemoglobiophaties that is Similar to beta thalassemia major

A

Hemoglobin E-Thalassemia

147
Q

Hemoglobin E-Thalassemia

Common in __

A

Cambodia, Thailand, part of India

148
Q

LABORATORY FINDINGS OF THALASSEMIA

A
  1. CBC
  2. Peripheral smear
  3. increased reticulocyte count
  4. bone marrow examination
  5. decreased OFT
  6. supravital stain
  7. electrophoresis
  8. Mass spectrophotometry
  9. DNA analysis (sophisticated test)
  10. increased indirect bilirubin.
149
Q

(sophisticated test) for thalassemia

A

DNA analysis
a. PCR
b. signal amplification system

150
Q

disorder in the DNA synthesis of RBC

A

Megaloblastic anemia

151
Q

the maturation of nucleus is delayed relative to that of cytoplasm

A

Megaloblastic anemia

152
Q

Types of megaloblastic anemia

A

Pernicious anemia - VitB12
Decrease level of Folic Acid

153
Q

Decrease level of Vitamin B₁₂ = Vitamin
B12 (cobalamin) deficiency

A

Pernicious anemia

154
Q

Folic Acid:
Important ito kapag buntis, so dapat so dapat meron ka nito baka
mauwi sa tinatawag na ___ (

A

Spina Bifida

155
Q

Vitamin B12 deficiency effects

A

Neurologic symptoms:
 Memory loss
 Numbness
 Tingling in toes and fingers
 Impairment of walking by loss of vibrator sense.

156
Q

Causes of Megaloblastic Anemia

A
  1. Inadequate intake sources of folic acid
  2. Increased need
  3. Impaired absorption in the intestine
  4. Impaired use due to drugs such as antiepileptic drugs
  5. Excessive loss during renal dialysis
157
Q

TEST for megaloblastic anemia

A

Shilling test

This test will determine or distinguish whether the problem is impaired absorption or malabsorption of B12 from other causes.

158
Q

Laboratory Findings of Megaloblastic Anemia:

A
  1. CBC
  2. Decreased in absolute reticulocyte count
  3. Peripheral smear
  4. Hypersegmented neutrophil(5 or more lobes)
159
Q

Laboratory Findings of Megaloblastic Anemia:

cbc

A

 Pancytopenia = Low/decreased formed elements
 Hb and Hct: decreased
 MCV: increased (>120 fL)
 MCH and RDW: increased
 MCHC: normal

160
Q

Peripheral smear of Megaloblastic Anemia:

A

a. oval macrocytes/megalocytes
b. poikilocytosis - dacryocytes, fragments, microspherocytes
c. NRBCs
d. Howell-Jolly bodies
e. Basophilic stippling
f. Cabot rings

161
Q

This is one of the hallmark of the condition
megaloblastic anemia

A

Hypersegmented neutrophil(5 or more lobes)

162
Q
  1. Chemistry Analysis of megaloblastic anemia
A

 decreased serum Folate level
 decreased serum Vitamin B₁₂ level
 increased Homocysteine – Folate def.
 increased Methylmalonic acid – B12 def.
 increased LDH
 increased total and indirect bilirubin

163
Q

increased LDH i megaloblastic anemia

A

lysis or destruction dun
palang sa bone marrow

164
Q

used to distinguish malabsorption of vitamin B12 from
other causes of malabsorption

A

Schilling Test

165
Q

uses oral dose of radioactive vitamin B12

A

Schilling Test

166
Q

Non-megaloblastic anemia causes

A

anemia caused by conditions such as alcoholism and chronic liver disease (CLD)

no hypersegmentation
no increase in MCV (di na umaabot more than 120)
Di namimeet 120 days lifespan (RBC)

167
Q

characterized by premature RBC destruction caused by autoantibodies that bind the RBC surface

A
  1. Autoimmune Hemolytic Anemia
168
Q

A. Extrinsic Hemolytic Anemia

  1. Antibody Mediated Anemia
    a) Autoimmune Hemolytic Anemia

what are the types of Autoimmune Hemolytic Anemia

A

a. Warm-Reactive Autoimmune Hemolytic Anemia
b. Cold-Reactive Autoimmune Hemolytic Anemia
c. Paroxysmal Cold Hemoglobinuria (PCH)

169
Q

a type of autoimmune hemolytic anemia

responsible for approximately 70% of Immune
hemolytic cases - mediated by antibody with maximum binding
affinity
at 37°C

A

a. Warm-Reactive Autoimmune Hemolytic Anemia - responsible for approximately 70% of Immun

170
Q

a type of autoimmune hemolytic anemia

mediated by antibody with maximum binding
affinity at 4°C or below 32°C

A

Cold-Reactive Autoimmune Hemolytic Anemia

171
Q

a type of autoimmune hemolytic anemia

a rare acute form of cold-generated hemolysis - hemolysis occurs when blood is warmed after
previous exposure to chilling - caused by an antibody (Donath-Landsteiner
antibody) present in the plasma

A

Paroxysmal Cold Hemoglobinuria (PCH)

172
Q
  • self-limiting, but severe even fatal following the administration of
    drug that can cause immune hemolytic anemia
A

Drug-Induced Immune Hemolytic Anemia

173
Q

example of drugs in Drug-Induced Immune Hemolytic Anemia

A

a. Penicillin
b. Stibophen
c. Alpha methyldopa

174
Q

usually occurs in newborns following the transplacental passage
of maternal anti-fetal red cells antibody.

A

Alloimune Hemolytic Anemia

175
Q

2 causes of Alloimune Hemolytic Anemia

A
  1. Erythroblastosis fetalis - Isoimmune HDN due to Rh incompatibility
  2. Isoimmune HDN due to ABO incompatibility
176
Q
A