Final Skin Cont. Flashcards
Risks for basal cell carcinoma
Cumulative UV
PTCH (hedgehog pathway)
TP53
Raised pearly papule with telangiectasia
Basal cell carcinoma
2nd MC skin cancer
Squamous cell carcinoma
SCC MC in older adults or
People with xeroderma pigmentosum
1% of SCC mets via
Local lymphatics
Benign tumor of melanocytes
Melanocytic Nevus
Moles are acquired, usually within
First 2 decades
Grows into dermis
Dysplastic Nevus
Benign growth with Dysplasia
Familial dysplastic Nevus
Higher cancer risk (melanoma)
Sporadic dysplastic Nevus
Low cancer risk
3rd MC skin cancer
Melanoma
Risks for melanoma
Intense UV
Family history in 10% cases
Striking variation, including black, brown, red, dark blue, grey with irregular boarders describes
Melanoma
Melanoma mets to
Liver
Lungs
CNS
Heart
ABCDs of melanoma
Asymmetry
Boarder
Color
Diameter