final review(24- Flashcards
mucosa, submucosa, muscularis, serosa
layers of gi tract
inner lining of GI tract
- epithelium protection, secretion, absorption
- lamina propria connective tissue w/ blood and lymphatic vessels and mucosa associated lymphatic
- muscularis mucosa thin layer of smooth muscle making folds to increase surface area
mucosa of gi tract
connective tissue binding to mucosa to muscularis and contains blood and lymphatic vessels [submucosal plexus)
submucosa of gi tract
has voluntary skeletal muscle found in mouth, pharynx, esoph, and anal sphincter; involuntary is elsewhere with myenteric plexus btwn muscle layers
muscularis of gi tract
outermost covering of organs suspended in abdominopelvic cavity aka visceral peritoneum; esophagus lacks serosa bc has adventitia
serosa of gi tract
- Intrinsic set of nerves - “brain of gut”
- Neurons extending from esophagus to anus
- Myenteric plexus – GI tract motility
- Submucosal plexus – controlling secretions
enteric nervous system(digestive) ENS
LARGEST serous membrane of the body : parietal and visceral
peritoneum
secreted by salivary glands acting on starches which only monosaccarides can be absorbed and cont to act until inactivated by stomach acid
salivary amylase
secreted by lingual glands of tongue acts on triglycerides which becomes activated in acidic environment of stomach
lingual lipase
=Mucosa – protection against wear and tear
=Submucosa
=Muscularis divided into thirds
- Superior 1/3 skeletal muscle
- Middle 1/3 skeletal and smooth muscle
- Inferior 1/3 smooth muscle
of esophagus
___ regulates movement into esophagus and ___ regulates movement into stomach
upper esophageal spincter; lower esophageal spincter
act of swallowing; facilitated by secretions of saliva and mucus
STages:
(buccal)voluntary:bolus passed to oropharynx
(pharyngeal):involluntary passage thru pharynx into esoph
(esophagea)l:involuntary passage thru esophagus to stomach using peristalisis pushes bolus forward
deglutition
serves as mixing chamber and holding reservoir; regions include cardia, fundus, body, plyorus
stomach
in mucosa of stomach the exocrine gland cells include
Mucous neck cells (mucus) Parietal cells (intrinsic factor and HCl) Chief cells (pepsinogen and gastric lipase)
- cephalic phase prepares stomach for arrival of food
- gastric phase enhances secretion from 1t phase and initiates digestion of protiens by pepsin
- intestinal phase controls rate of chyme entry into duodenum
phases of gastric secretion
99% of cells are acini [exocrine secrete pancreatic juice mixture of fluid and digestive enzymes]
-1% are pancreatic islets [endocrine secreting hormones glucagon, insulin, somatostatin, and pancreatic polypeptide]
pancreas
major functional cells of liver that secrete bile
hepatocytes
Mostly water, bile salts, cholesterol, lecithin, bile pigments and several ions
Partially excretory product/ partially digestive secretion
bile
- Derived from heme of recycled RBCs
- Breakdown product stercobilin gives feces brown color
bilirubin [principal bile pigment]
small intestine regions include
duodenum, jejunum, ileum
contains absorptive cells , goblet cells (mucus), intestinal glands (intestinal juice), Paneth cells(lysozyme), and enteroendocrine cells
mucosa of small intestine
- Permanent ridges of mucosa and submucosa
- Cause chyme to spiral
plicae circulares of small intestine modificiation
Fingerlike projections of mucosa
-Contains arteriole, venule, blood capillary, and lacteal
villi of small intestine
Fingerlike projections of apical membrane of absorptive cells
Brush border with brush border enzymes
microvillli
- Inserted into plasma membrane of absorptive cells
- Some enzymatic digestion occurs at surface rather than just in lumen
- α-dextrinase, maltase, sucrase, lactase, aminopetidase, dipeptidase, nucleosidases and phosphatases
brush border enzymes
mechanical digestion of small intestine is governed by ___ plexus
myenteric
cecum, colon, rectum, and anal canal with ileocecal sphincter btwn small and large intestine
large intestine
Remove electrons and pass them through electron transport chain to oxygen
oxidative phosphorylation
=oxidation of one glycose molecule to 2 pyruvic acid
=consumes 2 ATP but generates 4
glycolysis