Final Exam: Cardio/lymph/CNS/Musculoskeletal

Question 1

Which of the following organisms does not have a predilection for nervous tissue?

Cryptococcus neoformans
Histophilus somni
Listeria monocytogenes
Salmonella

Answer 1

Salmonella (GI tract is predilection site)

Question 2

Pleocytosis is the presence of:

Answer 2

increased number of cells in the cerebrospinal fluid

Question 3

T/F: Bacteriostatic agents are a good choice for treating infections of the CNS

Answer 3

FALSE

Bactericidal is best

Question 4

Histophilus somni causes what dz in cattle?

Answer 4

Thromboembolic menigoencephalitis (TEME) or Thrombotic meningoenephalitis (TME)

*usually occurs 1-2 weeks after episode of pneumonia, blindness, ataxia, convulsions, depression and coma – death in ~ 12 hrs

Question 5

What are pathognomonic lesions of Histophilus somni?

Answer 5

Multiple reddish necrotic foci, thrombi in blood vessels composed of leukocytes, fibrin

Question 6

What time of year do you see outbreaks of listeriosis?

Answer 6

Winter - spring

usually occurs after ingestion of contaminated silage during winter time

Question 7

What is the best sample to collect for listeriosis testing?

Answer 7

Brain stem

Question 8

T/F: Listeria cultures need to be specifically requested; normal culture will not work well

Answer 8

TRUE

Question 9

What is the drug of choice for listeriosis?

Answer 9

Penicillin

Question 10

What pathogen causes sporadic bovine encephalomyelitis in feedlot cattle?

Answer 10

Chlamydia pecorum

Question 11

Systemic infection by Salmonella dublin can cause ________ in calves

Answer 11

Meningitis

Question 12

What fungal infection can invade the CNS, most commonly in cats?

Answer 12

Cyptococcus

Question 13

What is the hallmark sign (at necropsy) of Clostridium perfringens type D in sheep?

Answer 13

Causes focal symmetrical encephalomalacia

*symmetrical necrosis and hemorrhage of the white matter

Question 14

What is traumatic reticulopericarditis?

Answer 14

hardware dz in cattle

Multiple bacteria will be involved

Question 15

T/F: the pathogen that causes black leg dz, can also cause pericarditits and myocarditis

Answer 15

TRUE

Question 16

Edema disease in weaned pigs is due to what pathogen?

Answer 16

Shigatoxigenic E. coli

generalized edema, edema of the eyelids and colon**

Question 17

What pathogen causes caseous lymphadenitis in sheep and goats?

Answer 17

Corynebacterium pseudotuberculosis

Question 18

Strangles is caused by ___________ in

Answer 18

Streptococcus equi subsp equi

Question 19

What does corynebacterium pseudotuberculosis cause in horses?

Answer 19

Pigeon fever - lymphangitis

Question 20

What pathogen causes lymphangitis in cats and horses?

Answer 20

Sporothrix schenkiii - dimorphic fungus

Question 21

What dimorphic fungi can cause severe osteomyelitis?

Answer 21

Coccidioides immitis

Arizona area

Question 22

Neorickettsia have an affinity for what cells?

Answer 22

macrophages

They replicate in enterocytes

Question 23

What causes Tropical pancytopenia? Who does it infect? What cells does it have an affinity for?

Answer 23

Ehrlichia canis - infects dogs

Affinity for haematopoietic and endothelial cells
*macrophages - can also colonize lymphocytes

Question 24

Ehrilicia ruminantium causes what disease?

Answer 24

Heart water dz in cattle

Question 25

What best diagnostic test for histotoxic clostridium?

Answer 25

DFT: direct fluorescent antibody staining test

Question 26

Anaplasma platys infects what cells in what host?

Answer 26

Platelets in canines

Question 27

What pathogens cause “tick cattle fever”?

Answer 27

Anaplasma Marginale (found in the periphery of erythrocytes)

Babesia (found inside erythrocytes)

Question 28

What pathogen causes “hariy heel warts”?

Answer 28

Treponema spps in cattle

Papillomatous digital dermatitis

Question 29

Clostridium piliforme causes what dz in what animals?

Answer 29

Tyzzer’s DZ

Lab animals and horses

Causes necrotizing hepatitis

Question 30

Who is most commonly affected by Black leg disease? What is the causative agent?

Answer 30

Healthy, young cattle at pasture, in the summer are most at risk

Clostridium chauvoei

Question 31

Malignant edema can be seen in horses, small ruminants, and swine do to an infection of _______

Answer 31

Clostridium septicum

Increased risk of infection after IM injections, docking, sheaing, and lambing