Final - Concepts in Review: Flashcards
for glioblastoma multiforme you see: mitotic figures, ___________ or ________________. You see _____________ around the first one.
necrosis or vascular proliferation
pseudopalisading
massive destruction of upper motor neurons for CN 7 on one side causes lasting weakness of the contralateral _________________
lower quadrant of face
Visual fields for both sides of the world come into the ____________________
damage = hemispatial neglect
right parietal lobe
what brain regions are involved in smooth pursuit?
the flocculonodulus
These cells receive synaptic inputs from leg mechanoreceptors (e.g. muscle spindles and Golgi tendon organs), and then send their axons into the posterior spinocerebellar tract on the same side
Clarke’s nucleus
what inclusions have been found in degenerating ventral horn neurons in ALS?
TDP-43
Spongiform degeneration of the cerebral cortex: _______ disease
prion
parabrachial nucleus damage: ___________ breathing
anpneustic
halogenated anesthetics do 3 things:
- increase GABAa opening duration
- open K+ channels
- enhance glycine activity at channels
________ may deposit in the walls of small and medium size arteries leading to weakening of the vessel walls and hemorrhage
what is this called?
amyloid
cerebral amyloid angioplasty
________________ respiration - waxing and waning breathing pattern with a period of 10-20 seconds; seen with diencephalon damage, cardiac failure
Cheyne-Stokes
white matter necrosis in the periventricular areas, thought to be caused by anoxia in preemies.
what white matter tracts does this commonly affect?
periventricular leukomalacia
motor tracts (can have spasticity and paralysis)
the ______ is active in wakefulness
the __________ inhibits this for SWS
the __________ is active in REM sleep. What does it do?
ARAS
medullary RF
pontine RF, excitatory for Ach neurons
the otoacoustic emissions are used to damped ________________
high frequencies
Repeated stimulation is required to maintain consciousness. Interactions with examiner are largely unproductive: __________ mental state
obtunded
on a CT, an acute bleed shows up how?
over time it:
looks very white
gets less bright, looks less dense. almost great and like rest of brain
what are the three eye BBBs?
Retinal-blood barrier
1) Tight junc9ons of the endothelial cells 2) Ciliary Epithelium
3) Retinal Pigment Epithelial cells (similar to arachnoid membrane)
a high MAC = _____ potency
low
for a stroke, the ADC scan is __________ and the DWI is _________
darker
brighter
what are the characteristic histological features of an ependymoma?
true rosettes (around a lumen)
perivascular rosettes (around a vessel)
decerebrate posturing in a come looks like what?
what damage does this indicate?
looks like a flexion, arms down hands out
damage below the rostral medulla
how are prion diseases characterized histologically?
spongiform degeneration of cerebral cortex