12.9 Formation/Modification/Repair

Question 1

there is an ____________ of neurons and processes in early development

Answer 1

overproduction

Question 2

segregation into ocular dominance columns needs ________ input

Answer 2

sensory

Question 3

there is ________ during development of the overproduction of synaptic processes

Answer 3

pruning

Question 4

in the ___________, sensory input shapes ocular dominance columns

Answer 4

critical period

Question 5

the neurons that get ______ and _____ keep the synaptic connection and the other ones prune

Answer 5

BDNF, NGF

Question 6

synaptic pruning depends on _________

Answer 6

use/activity

Question 7

window of time that the brain is expecting certain inputs, without this information the brain does not continue to develop normally.

Answer 7

critical period

Question 8

deficits acquired during the ______________ are permanent

Answer 8

critical period

Question 9

deficits acquired during the critical period are _________ (how long do they last)

Answer 9

permanent

Question 10

distal process of axon no longer receives axonal transport from the cell body.
Distal processes slowly degenerate and gets phagocytosed.

what is this called?

Answer 10

Wallerian degeneration

Question 11

cell body changes. Neuronal cell body swells. It’s nucleus moves to an eccentric position and it’s chromatin uncoils. Nissl bodies (RER in neurons) seem to dwindle, since the RER disperses to rev up synthesis

what is this called

Answer 11

chromatolysis

Question 12

Neurons postsynaptic to the axotomized neuron show degenerative changes.

____________ transneuronal degeneration

Answer 12

anterograde

Question 13

Neurons presynaptic to the axotomized neuron show degeneration changes

___________ transneuronal degeneration

Answer 13

retrograde

Question 14

what are the two areas on the brain where there is neurogenesis:

Answer 14

1. dentate of the hippocampus

2. the sub ventricular zone (goes to hippocampus)