FF Drogas: Anti-Hypertensives Flashcards
Most Common Loop Diuretic?
Lasix - Furosemide
Mechanism of Action of Lasix
- Inhibition of reabsorption of water and electrolytes from the loop Henle
General conditions in which diuretics would be utilized?
- HTN
- CHF
- Edema
- Pulmonary Edema
Side Effects of Loop Diuretics: Electrolyte Changes
- Hypokalemia
- Hypocalcemia
- Hyponatremia
Side Effects of Loop Diuretics: HR
Reflex Tachycardia; increased HR
Side Effects of Loop Diuretics: effects of decreased fluids
- OH
- Dizziness
- Dehydration
- Lethargy
What is an example of a Potassium Sparing Diuretic?
Spironolactone
- “Lactone”
Why might a potassium sparing diuretic be used?
When a patient has a high risk of hypokalemia
Adverse effects of Potassium Sparing Diuretics?
Similar to Loop Diuretics
+ Hyperkalemia
+ Gynecomastia
Main Thiazide Diuretic?
Hydrochlorothiazide (HCT)
Populations/conditions to avoid the use of Thiazide Diuretics?
- DM
- Renal Dysfunction
- Elderly
- Gout
What is Sparred with the used of Thiazide Diuretics?
CLUG:
- Calcium
- Lipids
- UREA
- Glucose
Thus leads to Hypercalcemia, Hyperuricemia, Hyperlipidemia
- similar side effects to a loop diuretic
ACE Inhibitors; Drugs
A-“PRILS”
- Captopril
- Enalapril
- Lisinopril
Mechanism of Ace Inhibitors?
Blocks Angiotensin Converting Enzyme
- Therefore preventing the formation of Aldosterone
Function of Aldosterone?
Retention of Na and Water and Kicks out Potassium
