Fetal/Neonatal Immunity Flashcards
What is the first organ to develop in a neonate?
thymus
What will occur if an animal is born without a thymus?
they will be immune deficient
Does a new born have a functional adaptive immune system?
NO
Cytopathic
strains induce IFN production and cannot cause persistent infection
Noncytopathic
strains do not trigger type 1 IFN production and can survive in calves and cause persistent infections
Maternal exposure to noncytopathic BVD can cause:
tolerance and persistent infection or normal
maternal exposure to cytopathic BVD can cause:
abortion, resorption or mummification
malformation
normal
Colostrum contains 65-90% which antibody in horses, cows, sheep, sow and queens
IgG
Colostrum is predominately which antibody in the bitch?
IgA
How long does a baby have to drink colostrum before Ig levels drop?
24 hours
When can you administer vaccines to a neonate?
after maternal antibodies stop being absorbed
Ingesting colostorum protects young animals against
septicemic disease
Ingesting milk for a long period of time ensure
GI protection against enteric infection
Reasons for failure of passive transfer
Production failure
ingestion failure
absorption failure