Female Repro Flashcards

1
Q

What forms the male and female tubular reproductive organs?

A

Wolffian tubules/ducts and Mullerian ducts

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2
Q

What part of the primordial germ cells migrate in to form the ovary?

A

Cortex

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3
Q

What part of the primordial germ cells migrate in to form the testis?

A

Medulla

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4
Q

What does the wolffian tubule and ducts form in the male and

Mullerian ducts in the female?

A

Male: Epididymus,
ductus deferens,
seminal vesicles,
ampulla

Female: Oviducts, uterus, cervix, anterior vagina

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5
Q

What does the urogenital sinus form in the male and female

A

Prostate
bulbourethral glands

Caudal Vagina

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6
Q

What does the gential tuburcle form in the male and female

A

Penis

Clitoris

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7
Q

What does the genital folds form in the male and female

A

prepuce

Vulva

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8
Q

What do the genital swellings form?

A

Scrotum

Vulva

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9
Q

Do males or female differentiate early on?

A

Males are earlier

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10
Q

What protein and factor induces undifferentiated gonad to develop into testes?

A

SRY protein

TDF

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11
Q

Which cell has Mullerian inhibitory substance and transcription factor important in diff of these cells

A

Sertoli Cells

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12
Q

What cells produce testosterone?

A

Interstital cells

specifically leydig cells

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13
Q

What does testosterone promotes and what else does it do?

A

Development of wolffian ducts

also converts DHT by the enzyme 5alpha reductase which induces development of penis,scrotum and prostate

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14
Q

What isn’t produced in females for sexual differentiation?

What is produced to help repress testicular development

A

SRY protein isn’t produced

DAX-1

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15
Q

What is a true hermaphrodite?

A

Someone who has both tissues in the gonadal tissue

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16
Q

what is a pseudohermaphrodite?

A

They will have male gonadal tissue or female gonadal tissue respectively

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17
Q

How does a freemartin occur?

A

Female calves are born co-twin with a male calf. There is a mixing of blood via large bore anastomoses with placentas so both calves will be chimeras bc the stem cells are mixed.

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18
Q

Why does a free martin occur?

A

MIS is produced in varying amounts in the female calf so the oviducts/uterus/cervix/anterio vagina do not develop properly

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19
Q

Is there communication of the cranial and caudal portions of the vagina in freemartins?

A

No!!!

also the external genitalia is normal to hypoplastic

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20
Q

What breed of dog does XX Sex reversal occur in?

A

Cocker Spaniels

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21
Q

What happens in XX sex reversal

A

Gonadal sex does not follow chromosal sex. XX true hermaphrodites and XX males.

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22
Q

XX true hermaphrodites are?

A

partially masculinized females with ovatestes

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23
Q

What are male pseudohermaphrodites?

A

They have 10% testicular tissue. Their external genitalia is malformed and are cyptorchid aspermatogenic testis

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24
Q

Why do these animals have abnormal development?

A

it is associated with an insertion on chromosome 9 and downregulation of RSPO1 in dogs.

Decreased or loss of this function can cause female to male sex reversal

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25
What spp does androgen insensitivity syndrome happen in?
Horses---male pseudohermaphrodites
26
What happens in Androgen insensitivity syndrome?
There is no target organ receptor for testosterone so the wolffian ducts regress external genitalia female. XY genotype SRY produced
27
What breed is persistent mullerian duct syndrome happen in?
Miniature schnauzers
28
What is the genotype and what happens in Persistant mullerian duct syndrome?
XY 50% have intra-abdominal testes There is no functional MIS receptors bc of a mutation encoding for a premature stop codon in the MIS Type 2 receptor They will have male external genitalia but oviducts, uterus, cervix and anterior vaginas
29
Who is uterine prolapses common in?
Cattle
30
What does uterine prolapse follow?
often follows dystocia retained placentas hypocalcemia
31
What are uterine ruptures associated with?
Pregnancy/parturition Obstetrical manipulations Prolongued dystocia, torsion
32
What kind of stitch do you use for a uterine prolapse?
Buhner stitch
33
Whats the name of the congenital disorder where a hyman without an opening completely obstructs the vagina
Imperforate hymen
34
What can be caused by persistent Wolffian duct remnants and what can this cause
Gartners duct cyst hyperestrogenism, infections
35
What are the viruses that can cause inflammation of the vagina and vulva?
IPV ECE
36
What body part becomes cystic when its opening into the lateral wall of the vaginal vestibule becomes obstructed?
Cystic Bartholins Gland
37
What are the common neoplasias of the vagina and vulva
Leiomyoma TVT Fibropapilloma SCC Melanoma
38
What are the two groups of bovine mastitis
Contagious-bact that have the external surface oft he udder and teat lesions as their preferential home. Environmental-bacteria from environment that contaminates the mammary gland
39
What are the bacteria that causes contagious bovine mastitis
Strep agalactiae, dysgalactiae Staph aureus Mycoplasma
40
In this acute type of mastitis you can see heremia/edema, strands and flecks of debris in milk and usually more than one quarter is invovled
Strep aglactiae
41
Which strep is more severe?
aglactiae
42
Which bact causes swollen, warm, edematous quarters
strep dysgalactiae
43
Staph aureus is coagulase positive or negative?
Positive
44
What causes varying virulences in stap mastitis
Depends on the virulence factors produced/possessed by the isolate of stap aureus invovled
45
Can staph cause gangrenous mastitis
Yes-usually around calving
46
Which bact causes nodules within the parenchyma
mycoplasma
47
What are your environmental mastitis
Coliform bacillus cereus Step uberis Coagulase negative staph truepurella
48
Endotoxins from coliforms acts on?
Vasculature-constriction.
49
Are coagulase negative staphs hot?
no
50
What is also called summer mastitis or dry cow mastitis?
trueperella
51
What is the most common bacterial cause of mastitis?
trueperella
52
What are the causes of mastitis in small ruminants
staph aureus mannheimia coliforms mycoplasma
53
Which bacteria causes mastitis close to the end of lactation
manheimia
54
Which bacteria causes high fever, depression, lethary, elevated HR, during post-partum period, the endotoxic can cause shock which can lead to death
Coliforms
55
Which bacteria causes mastitis mainly in goats?
Mycoplasma agalactiae
56
Survivors of mycoplasma agalactiae can develop what? who is the bact common in again?
Goats Ocular infections arthritis
57
Subclinical cases of mastitis in sm rum causes?
Hardbag
58
What virus can cause mastitis in sm rum?
Visna maedi-Lentivirus CAE-lentivirus
59
Who does mammary fibroadenomatous hyperplasia occur in, and how can you fix this
Cats young intact females one or several glands spontaneous regression or spay
60
Which two glands does mammary lobular hyperplasia occur in and who?
Caudal two glands bitch
61
Which spp primary has mammary adenomas/carcinomas
Dogs
62
What are the tumors of the cryptorchid testes?
Sertoli cell tumors | Seminomas
63
What could be a cause for testicular hypoplasia
Nutritional Zinc deficiency Chromosomal endocrine
64
Testicular hypoplasia vs atrophy?
Epididymuis is also small
65
Whats it called when animals have more than one cytogenetically distinct population of cells
Mosaics and Chimeras
66
Different cell types arise from th esame fertilized egg is a mosaic or chimera? What is their sex genetically
Mosaic XXY
67
Different cell types arise from different zygotes. Its a fusion of two fertilized ova or mixing of blood supplies in twining?
Chimera
68
Male tortoise shell and male calicos are?
Klinefelters syndrome
69
The gene for black and gene for orange are on different X chromosomes so a female cat may or may not have both colors under normal conditions. What inactivates?
X inactivation
70
What can cause testicular atrophy?
Secondary to a variety of insults including trauma, partial loss of blood flow, degeneration, thermal
71
whats the common cause of infertility
testicular degeneration
72
What are some causes of thermal testicular degenerations
Cyrptorchid Increased scrotal fat scrotal lesions environmental temps adhesions
73
What are some causes of testicular degeneration
Thermal Infectious conditions Nutritional deficiencies Vascular lesions Obstructive lesions toxins hormonal factors
74
What does testicular degeneration look grossly and microscopically?
Grossly, smaller and firmer Micro: Small seminiferous tubules containing small numbers of spermatogonia, spermatocytes, few to no mature sperm
75
Inflammation of: Testicles epididymis spermatichord
orchitidis epididymitis funucilitis
76
What are the routes for orchiditis and what are some causes
Usually infectious agents hematogenous extension retrograde*****