Fatty Acids (Section 2)

Question 1

Tricylglycerol Catabolism (how to begin breakdown)

Answer 1

breaking down tricylglycerol.
begin breakdown by adding H2O to 3 distinct hydrolysis reactions, each catalyzed by hormone-sensitive lipase.
Tricylglycerol esterification and lipolysis occur in the cytosol

Question 2

If glycerol becomes DHAP and goes through glycolysis, how many ATP do we get?

Answer 2

~19 ATP

Question 3

A fatty acid chain is shortened 2-C at a time. What is the name of this process?

Answer 3

Beta-oxidation. Converts C’s into Acetyl-CoA

Question 4

Where does Beta-oxidation occur?

Answer 4

mitochondria

Question 5

If we combusted the entire triglyceride molecule, how many ATP would it produce if composed of 3, 16-C fatty acid chains?

Answer 5

~318 + 19
1 Krebs Cycle oxidation of Acetyl-CoA = 80 ATP (10 ATP each C-chain, not each individual C; 10 ATP x 8)
1 Direct oxidation of Acetyl-CoA = 27 ATP
Total or 1, 16-C = 107 ATP
Multiple 107 by 3, 16-C fatty acid chains = 321 ATP