F-H Flashcards
1
Q
Another name for organophosphates
A
Parathion, Malathion
2
Q
Organophosphates MOA
A
Binds to acetylcholine, forming a stable phosphate-ester bond -> inactivation of Ache -> increased Ach
3
Q
Signs and symptoms of organophosphates
A
DUMBELS
4
Q
Treatment for organophosphate toxicity
A
Atropine
5
Q
Aid for the treatment -> enzyme deactivation (Acetylcholinesterase)
A
Pralidoxime
6
Q
Diagnosis for myasthenia gravis (muscle weakness)
A
Endrophonium
7
Q
Effect of organophosphate
A
Delayed neurotoxicity
8
Q
The clinical approach to management- Not persistent toxicant
A
Carbamate
9
Q
Moa of carbamate
A
Reversible binding to Ache
10
Q
Signs and symptoms of Carbamate
A
DUMBELS
11
Q
Treatment for carbamate toxicity
A
Atropine, Pralidoxime
