F - 18 - Haloperidol Flashcards

1
Q

MOA of Haldol

A
  • blockage of post-synaptic dopaminergic-R —> depression of reticular activating system
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2
Q

Serious effects of haloperidol

A
  • QT prolongation —> Torsades
  • broncho/laryngospasm
  • orthostatic hypotension
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3
Q

Prolonged QTc in men

A

Over 440 ms

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4
Q

Prolonged QTc in women

A

Over 460 ms

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5
Q

QTc over _____ associated with Torsades

A

500 ms

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