F - 18 - Haloperidol Flashcards
1
Q
MOA of Haldol
A
- blockage of post-synaptic dopaminergic-R —> depression of reticular activating system
2
Q
Serious effects of haloperidol
A
- QT prolongation —> Torsades
- broncho/laryngospasm
- orthostatic hypotension
3
Q
Prolonged QTc in men
A
Over 440 ms
4
Q
Prolonged QTc in women
A
Over 460 ms
5
Q
QTc over _____ associated with Torsades
A
500 ms