extra antimicrobial Q's Flashcards
I put this separately because its just drug memorization
When a patient has an enterococci infection, which of the following should you give him?
a. penicillin
b. cephalosporin
a. penicillin
cephalosporin is less active against enterococci
Which TWO of the following is active against Pseudomonas app.?
a. Cephalexin
b. Ceftazidime
c. Cefuroxime
d. Cefoxitin
f. Cefotaxime
d. Cefazolin
e. Cephepime
b. Ceftazidime
&
e. Cephepime
When a patient is allergic to penicillin, should a physician use cephalosporin instead?
No, there’s a cross reaction of 10%
use glycopeptides instead
Which of the following is usually mixed with cilastatin?
a. meropenem
b. imipenem
c. aztreonam
b. imipenem
Which of the following does NOT cause seizures?
a. meropenem
b. imipenem
c. aztreonam
c. aztreonam
beta-lactams are
a. bacteriostatic
b. bactericidal
b. bactericidal
Which is FALSE about the first natural penicillin?
a. produced by penicillum
b. broken down by gastric acids
c. broad range
d. high excretion rate
c. broad range
Which of the following is an oral penicillin?
a. piperacillin
b. temocillin
c. penicillin V
d. benzyl & procaine penicillin
c. penicillin V
Which of the following is anti-pseudomonas aeruginosa?
a. piperacillin
b. temocillin
c. penicillin V
d. benzyl & procaine penicillin
a. piperacillin
Which of the following is beta-lactamase resistant?
a. piperacillin
b. temocillin
c. penicillin V
d. benzyl & procaine penicillin
b. temocillin
Which of the following is active against Hemophilus?
a. Cefuroxime
b. Cefazolin
c. Cephalexin
a. Cefuroxime
also active against S. pneumoniae
Which of the following can be used for meningitis?
a. cefotaxime
b. cefoxitin
c. cloxacillin
d. cefazolin
a. cefotaxime
cefotaxime and ceftriaxone can cross the BBB
Which of the following is given parenterally?
a. piperacillin
b. temocillin
c. penicillin V
d. benzyl & procaine penicillin
d. benzyl & procaine penicillin
Which of the following is anti-staph?
a. ceftazidime
b. cefoxitin
c. cloxacillin
d. cefazolin
c. cloxacillin
Which of these is used against enterobacteria?
a. Cephalexin
b. Amoxicillin
c. Ceftazidime
b. Amoxicillin
it’s an extended-spectrum penicillin, while A&C are cephalosporin
Which of these isn’t a side effect of Penicillin?
a. vesicular rash
b. neurotoxicity
c. anapylactic reaction
d. urticarial reaction
a. vesicular rash
should be maculopapular rash. tricked you!
What occurs when you add an additional carbon to a drug?
a. pharmacokinetic activity decreases
b. the drug becomes more excretable
c. antibacterial activity is enhanced
c. antibacterial activity is enhanced
Which of the following can be treated aztreonam?
a. gram negative anaerobic cocci
b. gram negative aerobic cocci
c. gram negative anaerobic bacilli
d. gram negative aerobic bacilli
d. gram negative aerobic bacilli
Which of the following is more nephrotoxic?
a. vancomycin
b. teicoplanin
a. vancomycin
should monitor levels on blood
Which of the following stops protein synthesis?
a. Sulphonamides & Trimethoprim
b. Rifampicin
c. Nitrofurantoin
d. Quinolones
c. Nitrofurantoin
by messing with mRNA
Which of the following inhibit DNA dependent RNA polymerase?
a. Sulphonamides & Trimethoprim
b. Rifampicin
c. Nitrofurantoin
d. Quinolones
b. Rifampicin
What do Sulphonamides & Trimethoprim do?
a. directly inhibit DNA synthesis
b. directly inhibit DNA-gyrase
c. indirectly inhibit DNA synthesis
d. indirectly inhibit DNA-gyrase
c. indirectly inhibit DNA synthesis
What do Quinolones do?
a. directly inhibit DNA synthesis
b. directly inhibit DNA-gyrase
c. indirectly inhibit DNA synthesis
d. indirectly inhibit DNA-gyrase
b. directly inhibit DNA-gyrase
which of these inhibits dihydrofolate reductase?
a. sulphonamide
b. trimethoprime
b. trimethoprime
What occurs when you give a person with a G6PD deficiency sulfonamide?
a. hematuria
b. hemolytic anemia
c. megaloblastic anemia
b. hemolytic anemia
Which of these can cause stevens-johnson syndrome?
a. trimethoprim
b. sulphonamide
c. vancomycin
b. sulphonamide
Which of the following is NOT used for UTI’s?
a. trimethoprime
b. nitrofurantoin
c. quinolones
d. ciprofloxin
c. quinolones
Which TWO of these cause pseudomembranous colitis
a. cephalosporin
b. glycopeptides
c. meropenem
d. quinolones
e. metronidazole
a. cephalosporin
&
d. quinolones
(& clindamycin)
Which of these cause a metalic tast to occur?
a. cephalosporin
b. glycopeptides
c. meropenem
d. quinolones
e. metronidazole
e. metronidazole
Which of these inhibits DNA gyrase?
a. Cefotaxime
b. Ciprofloxacin
c. Cefazolin
d. Cephepime
b. Ciprofloxacin
which is a flouroquinolones
Patient presents with giardia lamba, what should you treat him with?
metronidazole
its for anaerobes and protozoa
What occurs when you give a person with a G6PD deficiency nitrofurantoin?
a. hematuria
b. hemolytic anemia
c. megaloblastic anemia
b. hemolytic anemia
hemolysis
Which of the following destroy the cell wall first?
a. glycopeptide
b. penicillin
c. cephalosporin
a. glycopeptide
they act on wall synthesis before the beta lactams
Which of these inhibit the earlier stages of folic acid synthesis?
a. sulphonamide
b. trimethoprime
a. sulphonamide
How do macrolides stop protein synthesis?
a. bind to 30S ribosome
b. bind to 50S ribosome
b. bind to 50S ribosome
clindamycin does this too!
Which of the following is known to be nephrotoxic and ototoxic?
a. gentamicin
b. josamycin
c. erythromycin
a. gentamicin
which of the following has a side effect of clostridium difficile-associated diarrhea?
a. gentamicin
b. josamycin
c. erythromycin
d. clindamycin
d. clindamycin
Which of the following binds to 30S ribosome to stop protein synthesis?
a. clindamycin
b. tetracycline
c. josamycin
b. tetracycline
Which is used for RTI and STD treatment?
a. clindamycin
b. tetracycline
c. azithromycin
d. amikacin
c. azithromycin
along with other macrolides like erythromycin, josamycin, & clarithromycin
Which of the following is used for severe sepsis?
a. amikacin
b. josamycin
c. erythromycin
d. clindamycin
a. amikacin
any aminoglycoside; like amikacin, gentamicin, & streptomycin
Which of the following is used to treat rickettsia?
a. clindamycin
b. tetracycline
c. azithromycin
d. amikacin
b. tetracycline
used for atypical bacteria
Which two of the following is bacteriocidal?
a. fusidic acid
b. chloramphenicol
c. colistin
d. tetracycline
e. aminoglycosides
c. colistin
&
e. aminoglycosides
which of the following has a side effect of irreversible bone marrow aplasia?
a. fusidic acid
b. chloramphenicol
c. colistin
d. tetracycline
b. chloramphenicol
which of the following is never used alone because of fear of resistance?
a. fusidic acid
b. chloramphenicol
c. colistin
d. tetracycline
a. fusidic acid
Which of these stops the protein synthesis initiation process?
a. colistin
b. linezolid
c. fusidic acid
b. linezolid
oxazolidinones
Which of the following damages cartilage?
a. tetracycline
b. quinolone
c. chloramphenicol
b. quinolone
& ciprofloxacin
Which of the following causes grey baby syndrome?
a. tetracycline
b. quinolone
c. chloramphenicol
c. chloramphenicol
Which of the following damages cartilage?
a. colistin
b. linezolid
c. ciprofloxacin
d. fusidic acid
c. ciprofloxacin
& quinolone
Which of these has an anti-endotoxin activity that neutralizes LPS?
a. colistin
b. linezolid
c. fusidic acid
a. colistin
