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I&I Past Exams > extra antimicrobial Q's > Flashcards

extra antimicrobial Q's Flashcards

I put this separately because its just drug memorization

1
Q

When a patient has an enterococci infection, which of the following should you give him?

a. penicillin
b. cephalosporin

A

a. penicillin

cephalosporin is less active against enterococci

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2
Q

Which TWO of the following is active against Pseudomonas app.?

a. Cephalexin
b. Ceftazidime
c. Cefuroxime
d. Cefoxitin
f. Cefotaxime
d. Cefazolin
e. Cephepime

A

b. Ceftazidime
&
e. Cephepime

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3
Q

When a patient is allergic to penicillin, should a physician use cephalosporin instead?

A

No, there’s a cross reaction of 10%

use glycopeptides instead

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4
Q

Which of the following is usually mixed with cilastatin?

a. meropenem
b. imipenem
c. aztreonam

A

b. imipenem

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5
Q

Which of the following does NOT cause seizures?

a. meropenem
b. imipenem
c. aztreonam

A

c. aztreonam

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6
Q

beta-lactams are

a. bacteriostatic
b. bactericidal

A

b. bactericidal

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7
Q

Which is FALSE about the first natural penicillin?

a. produced by penicillum
b. broken down by gastric acids
c. broad range
d. high excretion rate

A

c. broad range

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8
Q

Which of the following is an oral penicillin?

a. piperacillin
b. temocillin
c. penicillin V
d. benzyl & procaine penicillin

A

c. penicillin V

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9
Q

Which of the following is anti-pseudomonas aeruginosa?

a. piperacillin
b. temocillin
c. penicillin V
d. benzyl & procaine penicillin

A

a. piperacillin

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10
Q

Which of the following is beta-lactamase resistant?

a. piperacillin
b. temocillin
c. penicillin V
d. benzyl & procaine penicillin

A

b. temocillin

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11
Q

Which of the following is active against Hemophilus?

a. Cefuroxime
b. Cefazolin
c. Cephalexin

A

a. Cefuroxime

also active against S. pneumoniae

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12
Q

Which of the following can be used for meningitis?

a. cefotaxime
b. cefoxitin
c. cloxacillin
d. cefazolin

A

a. cefotaxime

cefotaxime and ceftriaxone can cross the BBB

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13
Q

Which of the following is given parenterally?

a. piperacillin
b. temocillin
c. penicillin V
d. benzyl & procaine penicillin

A

d. benzyl & procaine penicillin

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14
Q

Which of the following is anti-staph?

a. ceftazidime
b. cefoxitin
c. cloxacillin
d. cefazolin

A

c. cloxacillin

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15
Q

Which of these is used against enterobacteria?

a. Cephalexin
b. Amoxicillin
c. Ceftazidime

A

b. Amoxicillin

it’s an extended-spectrum penicillin, while A&C are cephalosporin

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16
Q

Which of these isn’t a side effect of Penicillin?

a. vesicular rash
b. neurotoxicity
c. anapylactic reaction
d. urticarial reaction

A

a. vesicular rash

should be maculopapular rash. tricked you!

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17
Q

What occurs when you add an additional carbon to a drug?

a. pharmacokinetic activity decreases
b. the drug becomes more excretable
c. antibacterial activity is enhanced

A

c. antibacterial activity is enhanced

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18
Q

Which of the following can be treated aztreonam?

a. gram negative anaerobic cocci
b. gram negative aerobic cocci
c. gram negative anaerobic bacilli
d. gram negative aerobic bacilli

A

d. gram negative aerobic bacilli

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19
Q

Which of the following is more nephrotoxic?

a. vancomycin
b. teicoplanin

A

a. vancomycin

should monitor levels on blood

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20
Q

Which of the following stops protein synthesis?

a. Sulphonamides & Trimethoprim
b. Rifampicin
c. Nitrofurantoin
d. Quinolones

A

c. Nitrofurantoin

by messing with mRNA

21
Q

Which of the following inhibit DNA dependent RNA polymerase?

a. Sulphonamides & Trimethoprim
b. Rifampicin
c. Nitrofurantoin
d. Quinolones

A

b. Rifampicin

22
Q

What do Sulphonamides & Trimethoprim do?

a. directly inhibit DNA synthesis
b. directly inhibit DNA-gyrase
c. indirectly inhibit DNA synthesis
d. indirectly inhibit DNA-gyrase

A

c. indirectly inhibit DNA synthesis

23
Q

What do Quinolones do?

a. directly inhibit DNA synthesis
b. directly inhibit DNA-gyrase
c. indirectly inhibit DNA synthesis
d. indirectly inhibit DNA-gyrase

A

b. directly inhibit DNA-gyrase

24
Q

which of these inhibits dihydrofolate reductase?

a. sulphonamide
b. trimethoprime

A

b. trimethoprime

25
Q

What occurs when you give a person with a G6PD deficiency sulfonamide?

a. hematuria
b. hemolytic anemia
c. megaloblastic anemia

A

b. hemolytic anemia

26
Q

Which of these can cause stevens-johnson syndrome?

a. trimethoprim
b. sulphonamide
c. vancomycin

A

b. sulphonamide

27
Q

Which of the following is NOT used for UTI’s?

a. trimethoprime
b. nitrofurantoin
c. quinolones
d. ciprofloxin

A

c. quinolones

28
Q

Which TWO of these cause pseudomembranous colitis

a. cephalosporin
b. glycopeptides
c. meropenem
d. quinolones
e. metronidazole

A

a. cephalosporin
&
d. quinolones

(& clindamycin)

29
Q

Which of these cause a metalic tast to occur?

a. cephalosporin
b. glycopeptides
c. meropenem
d. quinolones
e. metronidazole

A

e. metronidazole

30
Q

Which of these inhibits DNA gyrase?

a. Cefotaxime
b. Ciprofloxacin
c. Cefazolin
d. Cephepime

A

b. Ciprofloxacin

which is a flouroquinolones

31
Q

Patient presents with giardia lamba, what should you treat him with?

A

metronidazole

its for anaerobes and protozoa

32
Q

What occurs when you give a person with a G6PD deficiency nitrofurantoin?

a. hematuria
b. hemolytic anemia
c. megaloblastic anemia

A

b. hemolytic anemia

hemolysis

33
Q

Which of the following destroy the cell wall first?

a. glycopeptide
b. penicillin
c. cephalosporin

A

a. glycopeptide

they act on wall synthesis before the beta lactams

34
Q

Which of these inhibit the earlier stages of folic acid synthesis?

a. sulphonamide
b. trimethoprime

A

a. sulphonamide

35
Q

How do macrolides stop protein synthesis?

a. bind to 30S ribosome
b. bind to 50S ribosome

A

b. bind to 50S ribosome

clindamycin does this too!

36
Q

Which of the following is known to be nephrotoxic and ototoxic?

a. gentamicin
b. josamycin
c. erythromycin

A

a. gentamicin

37
Q

which of the following has a side effect of clostridium difficile-associated diarrhea?

a. gentamicin
b. josamycin
c. erythromycin
d. clindamycin

A

d. clindamycin

38
Q

Which of the following binds to 30S ribosome to stop protein synthesis?

a. clindamycin
b. tetracycline
c. josamycin

A

b. tetracycline

39
Q

Which is used for RTI and STD treatment?

a. clindamycin
b. tetracycline
c. azithromycin
d. amikacin

A

c. azithromycin

along with other macrolides like erythromycin, josamycin, & clarithromycin

40
Q

Which of the following is used for severe sepsis?

a. amikacin
b. josamycin
c. erythromycin
d. clindamycin

A

a. amikacin

any aminoglycoside; like amikacin, gentamicin, & streptomycin

41
Q

Which of the following is used to treat rickettsia?

a. clindamycin
b. tetracycline
c. azithromycin
d. amikacin

A

b. tetracycline

used for atypical bacteria

42
Q

Which two of the following is bacteriocidal?

a. fusidic acid
b. chloramphenicol
c. colistin
d. tetracycline
e. aminoglycosides

A

c. colistin
&
e. aminoglycosides

43
Q

which of the following has a side effect of irreversible bone marrow aplasia?

a. fusidic acid
b. chloramphenicol
c. colistin
d. tetracycline

A

b. chloramphenicol

44
Q

which of the following is never used alone because of fear of resistance?

a. fusidic acid
b. chloramphenicol
c. colistin
d. tetracycline

A

a. fusidic acid

45
Q

Which of these stops the protein synthesis initiation process?

a. colistin
b. linezolid
c. fusidic acid

A

b. linezolid

oxazolidinones

46
Q

Which of the following damages cartilage?

a. tetracycline
b. quinolone
c. chloramphenicol

A

b. quinolone

& ciprofloxacin

47
Q

Which of the following causes grey baby syndrome?

a. tetracycline
b. quinolone
c. chloramphenicol

A

c. chloramphenicol

48
Q

Which of the following damages cartilage?

a. colistin
b. linezolid
c. ciprofloxacin
d. fusidic acid

A

c. ciprofloxacin

& quinolone

49
Q

Which of these has an anti-endotoxin activity that neutralizes LPS?

a. colistin
b. linezolid
c. fusidic acid

A

a. colistin

I&I Past Exams (14 decks)

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