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I&I Past Exams > 2014 I&I exam > Flashcards

2014 I&I exam Flashcards

1
Q

Which microorganism has a 100% risk of transfer to the fetus in the 10th week of gestation?

a. Rubella
b. Group B Strep
c. Toxoplasma Gondii
d. Treponema

A

a. Rubella

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2
Q

What technique requires extensive laboratory preparations?

a. CT
b. leukoscan
c. technetium-erythrocyte count
d. MRI
e. Indium-111 WBC count
f. Gallium 76
g. F18-FDG

A

e. Indium-111 WBC count

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3
Q

Which of the following is used to identify high rates of metabolism?

a. CT
b. leukoscan
c. technetium-erythrocyte count
d. MRI
e. Indium-111 WBC count
f. Gallium 76
g. F18-FDG

A

f. Gallium 76

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4
Q

Which organism colonizes the nostrils of health care workers?

a. chlamyde tracomatis
b. cornyobateryum deptheri
c. streptococus agalactiue
d. S.aurues

A

d. S.aurues

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5
Q

By which molecules do T lymphocytes recognize virus-infected cells?

a. CD4
b. CD8
c. MHC class l
d. MHC class ll

A

c. MHC class l

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6
Q

What stage in the spectrum of infectious disease is the most important in the transmission of the disease?

a. Clinical
b. carrier
c. recovery
d. subclinical

A

d. subclinical

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7
Q

What virus requires a high security infectious disease facility?

a. Ebola
b. hepatitis B
c. hepatitis C
d. HIV

A

a. Ebola

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8
Q

What is a feature of thymic cortex?

a. blood-thymus barrier
b. germinal center
c. plasma cells
d. primary nodules

A

a. blood-thymus barrier

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9
Q

During which stage is the thymus size the largest?

a. infancy
b. neonatal
c. puberty
d. childhood

A

c. puberty

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10
Q

What does Enteropathogenic E. coli use for attachment?

a. Outer membrane protein
b. Colonizing factor antigen I

A

a. Outer membrane protein

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11
Q

Which of the following exhibits ototoxicity as a side effect?

a. cefotaxime
b. ciprofloxacin
c. gentamycin
d. tetracycline

A

c. gentamycin

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12
Q

Which of the pathogens release enterotoxins while sporulating in the intestines?

a. C. Pefirenges
b. C. Botulinum
c. C. Tetanu
d. Yersinia Pestis

A

a. C. Pefirenges

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13
Q

What are the chances of the fetus to acquire syphilis if the mother is in the secondary stage?

a. 30%
b. 40%
c. 50%
d. 60%

A

c. 50%

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14
Q

Which organism commonly in AIDS leads to multiple brain absences?

a. pneumocystis jirovici
b. cryptococcus neophormans
c. nocardia asteroids
d. toxoplasma gondi

A

d. toxoplasma gondi

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15
Q

A person sustained a needle stick injury from an HIV positive person, when should the antiretroviral drugs be taken?

a. 3 days
b. 7 days
c. 10 days
d. 14 days

A

a. 3 days

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16
Q

What best describes fomiversin’s antiviral mechanism of action?

a. inhibits RNA polymerase.
b. prevents the early entry of viral particles into the cell
c. causes chain termination of viral DNA.
d. Blocks translation of viral mRNA into viral protein

A

d. Blocks translation of viral mRNA into viral protein

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17
Q

A newborn baby born at 36 weeks showed hydrops fetalis. He has hepatosplenomegaly icterus and encephalitis. Results showed intranuclear inclusions in large cells. What is the cause?

a. Parvovirus
b. Rubella
c. herpes simplex
d. CMV

A

d. CMV

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18
Q

Which genotype of HCV is highly resistant of interferon alpha and ribavirin?

a. Genotype 1
b. Genotype 2
c. Genotype 3
d. Genotype 4

A

a. Genotype 1

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19
Q

Which of the following cells has both cd4 and cd25?

a. B cell
b. Regulatory t cell
c. Nk cell
d. T helper cell

A

b. Regulatory t cell

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20
Q

Which of the following cells first appeared in viral infection??

a. NK cell
b. T cell
c. Ab
d. macrophages

A

a. NK cell

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21
Q

If the mother have HBV what is the chance for the fetus to develop the infection?

a. 20%
b. 30%
c. 90%

A

c. 90%

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22
Q

Which Method is best used for sterilization of Plasma Solutions?

a. Incineration
b. Autoclave
c. Membrane Filtration
d. Pasteurization

A

c. Membrane Filtration

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23
Q

What would you use to disinfect a blood spillage?

a. Hypochlorite
b. Betadine
c. Benzoic acid

A

a. Hypochlorite

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24
Q

A new born baby was suspected to have congenital syphilis what is the best specimen for diagnosis?

a. Blood
b. Stool
c. Placenta
d. Urine

A

c. Placenta

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25
Q

A 86 year old guy was admitted to the hospital with severe chest pain, after 10 days he developed a urinary tract infection. What is the most likely cause of the UTI?

a. E.coli
b. Pseudomonas aerigonosa
c. candida albicans

A

a. E.coli

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26
Q

Which of the following is used to prevent transmission of airborne droplet containing microorganisms (respiratory infection)?

a. Positive pressure room
b. N75 respirator Mask
c. N95 respirator Mask

A

c. N95 respirator Mask

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27
Q

Distribution of Indium-111 WBC was shown to be concentrated in the spleen, liver, whole spine area and the cecum. Which of the following is the final diagnosis?

a. Splenic abscess
b. Osteomyelitis of the spine
c. Diverticulitis
d. Hepatitis

A

c. Diverticulitis

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28
Q

Which one is associated with the central artery?

a. White pulp
b. Red pulp
c. germinal centers
d. splenic sinuses
e. splenic cords
f. trabeculae
g. marginal zone
h. lymphatic nodules

A

a. White pulp

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29
Q

After the spread of a virus in the hospital what is the best prophylaxis to be given to the health care workers and nurses?

a. Oseltamivir
b. Amantadine

A

a. Oseltamivir

30
Q

Killing bacteria by forming thymine dimers

a. Heat
b. UV rays
c. Steam

A

b. UV rays

31
Q

Which method is used to separate cell with specific cell antigen?
A. Agglutination
B. ELISA
C. Flow cytometry

A

C. Flow cytometry

32
Q

Which of the following causes pneumonitis in HIV patients?

a. HPV
b. CMV
c. VZV

A

b. CMV

33
Q

What is the type of vaccine used for yellow fever?

a. Live attenuated
b. Conjugated vaccine
c. Toxoid vaccine

A

a. Live attenuated

34
Q

Which of the following is true regarding MHC class II?

a. Involved in endogenous pathway
b. Involved in exogenous pathway

A

b. Involved in exogenous pathway

35
Q

Which of the following important in ADCC?

a. MHCI
b. MHCII
c. Fc receptor

A

c. Fc receptor

36
Q

Which of the following used for blood grouping?

a. Agglutination
b. Antibody-mediated
c. EIA

A

a. Agglutination

37
Q

Which of the following terms used for umbilical cord inflammation?

a. villitis
b. funcitis
c. umbilitis

A

b. funcitis

38
Q

What type of vaccine is BCG?

a. Conjugated vaccine
b. Attenuated vaccine
c. Toxoid vaccine

A

b. Attenuated vaccine

39
Q

What is shown on both helper and cytotoxic t cells?

a. CD4
b. CD8
c. CD3
d. CD25

A

c. CD3

40
Q

Which Antifungal is associated with gynecomastia and inhibition of testosterone synthesis?

a. Fluconazole
b. Ketoconazole
c. Voriconazole

A

b. Ketoconazole

41
Q

Which one of the following is associated with stagnant basal lamia/ basement membrane?

a. germinal centers
b. splenic sinuses
c. splenic cords
d. trabeculae

A

b. splenic sinuses

42
Q 
A tourist was visiting Thailand and he suffered from an infection after doing a laboratory exam it showed a spherical yeast-like cell; short hyphal (arthroconidia forms) divide by septum/fission?
A. Aspergillus
B. Mucor circinelloides
C. Penicillium marneffei
D. Coccidyotes
A

C. Penicillium marneffei

AKA- Talaromyces marneffei

43
Q

What is given as treatment to a patient w/swine flu (H1N1)?

a. Tetracycline
b. Oseltamivir
c. Chloramphenicol

A

b. Oseltamivir

44
Q

Which of the following antibiotics binds reversibly to 30s subunit?

a. Tetracycline
b. Macrolide
c. Clindamycin

A

a. Tetracycline

45
Q

In renal transplant patient, What is the most common manifestation of BK virus?

a. retinitis
b. nephropathy
c. haemorrhagic cystitis
d. Pneumonitis

A

b. nephropathy

46
Q

Which of the following is a component of Blood-Thymic barrier?

a. epithelioreticular Type 1
b. epithelioreticular Type 2
c. epithelioreticular Type 3
d. epithelioreticular Type 4

A

a. epithelioreticular Type 1

47
Q

What does Helicobacter pylori use for colonization?

a. coagulase
b. urease
c. haemagglutinin
d. protease

A

c. haemagglutinin

48
Q

Which of the following is a protease inhibitor?

a. nystatin
b. Indinavir
c. oseltamivir

A

b. Indinavir

49
Q

A group of 300 people were isolated in a hotel for 1 week after recognizing that one of the people in the hotel is diagnosed with A/H1N1, what is this called?

a. Quarantine
b. Elimination
c. Isolation

A

a. Quarantine

50
Q

What mechanism of Amphotericin B kills fungal cell?

a. Loss of K
b. Accumulation of K
c. Synthesis of ergosterol

A

a. Loss of K

51
Q

Which of the following has no absorption from mucous membrane or skin?

a. linezolid
b. nystatin
c. Vancomycin
d. dabtomycin

A

b. nystatin

52
Q

What is the most specific and sensitive method used to diagnose HSV?

a. DNA PCR
b. RNA PCR
c. Seroconversion

A

a. DNA PCR

53
Q

Is used to prevent transmission from person to health care environment?

a. Gloves
b. Hand washing

A

a. Gloves

54
Q

HIV-1 infected patient had developed multifocal leukoencephalopathy due to which pathogen?

a. BK virus
b. JC virus
c. HSV-1
d. HSV-2

A

b. JC virus

55
Q

What is the most infectious virus in a hospital setting?

a. varicella zoster virus
b. parvovirus
c. cytomegalovirus

A

a. varicella zoster virus

airborne transmission

56
Q

Which has both live and killed vaccines?

a. Polio vaccine
b. Yellow fever vaccine
c. HBV vaccine
d. Rabies vaccine

A

a. Polio vaccine

57
Q

Hyper-IgM result because of?

a. mutation in CD8 ligand
b. mutation in CD4 ligand
c. mutation in CD35 ligand
d. mutation in CD40 ligand

A

d. mutation in CD40 ligand

58
Q

What is the function of Bacillus anthracis capsule?

a. attachment
b. preventing phagocytosis
c. survive the acidic stomach

A

b. preventing phagocytosis

59
Q

Which technique is used to detect surface Antigen?

a. coagulase test
b. Immunofluorescence
c. hemagglutination
d. serology

A

b. Immunofluorescence

60
Q

What organism need oil supplementation for its growth?

A

Malassezia furfur

61
Q

Which of the following organism associated with heart Cross-reactive Auto-antigens autoimmune disease? (molecular mimicry)

a. Streptococcus pyogenes
b. Cryptococcus neoformans
c. Campylobacter pylori

A

a. Streptococcus pyogenes

62
Q

What do we call the process when we separate mononuclear cells from blood?

A

density gradient sedimentation

63
Q

What antibiotic inhibits the synthesis of folic acid in its early stage?

a. Sulphonamide
b. Trimethoprim

A

a. Sulphonamide

64
Q

a diabetic patient developed a rhino-cerebral infection with hemorrhage. A specimen was taken and it revealed non-septate hyphae. What is the causative organism?

a. Aspergilosis
b. Mucorales
c. Candida

A

b. Mucorales

65
Q

What can occur as a result of C3 deficiency?

A

Recurrent sinu-pulmonary infections

66
Q

what are the symptoms of the Exotoxin of streptococcus pyogen?

a. Pyrogenic effect
b. Necrosis of skin
c. Erythema

A

a. Pyrogenic effect

67
Q

Which of the following organisms cause transient bacteremia after tooth extraction?

a. staph aureus
b. staph epidermidis
c. strept viridans
d. strept pyogen

A

c. strept viridans

68
Q

Which of the following is transmitted from person to person in ICU setting?

a. Clostridium dificile
b. Clostridium botulism
a. Clostridium perfringens
a. Clostridium tetani

A

a. Clostridium dificile

69
Q

How are HLA class 1 molecules coded?
A. coded by HLA -A, -B, -C
B. codeed by HLA -DP, -DQ, -DR

A

A. coded by HLA -A, -B, -C genes

70
Q

Which of the following antibiotic works on inhibiting to topoisomerases?

a. Aztreonam
b. Nitofurantoin
c. Ciprofloxacin
d. Vancomycin

A

c. Ciprofloxacin

71
Q

What is used as a prophylaxis for Haemophilus influenza type b meningitis?

A

rifampicin

72
Q

Which of the following pathogens is carried through a vector (vector-mediated)?

a. Yellow fever
b. Escherichia coli

A

a. Yellow fever

I&I Past Exams (14 decks)

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