Exam 5 - 4/11 Flashcards

1
Q

Intellectual Disability -

American Psychiatric Association criteria of intellectual disability based on IQ < ___ and difficulty dealing with routine needs such as _________

A
  • 70

- self-care

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2
Q

Intellectual Disability -

A limitation in intellectual functioning and in _________ behavior

A

adaptive

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3
Q

Intellectual Disability -

Severity:

  • Mild
  • _________
  • Severe
  • _________
A
  • Moderate

- Profound

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4
Q

Intellectual Disability -

Deficits are based on adaptive functioning not IQ scores:

  • Communication
  • _________
  • Social participation
  • _________ functioning
A
  • Independence

- Occupational

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5
Q

Intellectual Disability -

Deficits are based on adaptive functioning not _________ scores:

A

IQ

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6
Q

Intellectual disability -

Definition of intellectual disability depends on _________ and situation

-Could function well in a _________ environment

A
  • culture

- simpler

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7
Q

Intellectual disability -

Disability is due to both _________ and _________ influences

A
  • genetic

- environmental

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8
Q

Intellectual disability -

_________ genes linked to mild disability – each gene has a small influence but effects of genes are _________

A
  • Four

- cumulative

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9
Q

Intellectual disability -

More than _________ physical disorders that cause intellectual disability – account for 25% of cases

A

200

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10
Q

Intellectual disability -

Maternal _________ is the leading cause of intellectual disability – _________ alcohol syndrome

A
  • alcoholism

- fetal

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11
Q

Down syndrome-

Most common _________ cause of intellectual disability

A

genetic

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12
Q

_________ -

Most common genetic cause of intellectual disability

A

Down syndrome

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13
Q

Down syndrome-

Caused by three copies of chromosome ___ (trisomy)

A

21

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14
Q

_________ -

IQ typically 40 – 55

A

Down syndrome

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15
Q

Down syndrome-

All Down syndrome individuals develop amyloid _________ and Alzheimer’s if live to age ___

A
  • plaques

- 50

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16
Q

Phenylketonuria-

Inability to metabolize _________, an amino acid

A

phenylalanine

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17
Q

Phenylketonuria-

Excess phenylalanine interferes with _________

A

myelination

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18
Q

Phenylketonuria-

Can cause profound _________ disability

A

intellectual

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19
Q

Phenylketonuria-

Newborns tested for levels of _________

A

phenylalanine

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20
Q

Phenylketonuria-

Controlled by _________ modification – eg, avoid aspartame which is high in phenylalanine

A

-diet

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21
Q

_________ -

Increased volume of cerebrospinal fluid in cerebral ventricles of brain crush surrounding tissue leading to intellectual disability in some but not all individuals

A

Hydrocephalus

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22
Q

Hydrocephalus -

Increased volume of cerebrospinal fluid in cerebral _________ of brain crush surrounding tissue leading to _________ disability in some but not all individuals

A
  • ventricles

- intellectual

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23
Q

Hydrocephalus -

Increased volume of _________ fluid in cerebral ventricles of brain crush surrounding tissue leading to intellectual disability in some but not all _________

A
  • cerebrospinal

- individuals

24
Q

_________ – includes early infantile autism, childhood autism, pervasive development disorder, and Asperger’s disorder etc.

A

Autism Spectrum Disorder

25
Autism - Persistent deficits in social _________ and social interaction across _________ contexts
- communication | - multiple
26
Autism - Restricted, repetitive patterns of _________, interests, or _________
- behavior | - activities
27
Autism - Symptoms must be present in the _________ development period
early
28
Autism - Symptoms cause clinically significant impairment in social, _________, or other important areas of _________ functioning
- occupational | - current
29
Autism - These disturbances are not better explained by intellectual _________ or global development delay
disability
30
Autism - Includes _________ impairment, compulsive, ritualistic behavior (rocking, flapping, head banging) as well as _________ disability
- social | - intellectual
31
Autism - Includes social impairment, _________, ritualistic behavior (rocking, _________, head banging) as well as intellectual disability
- compulsive | - flapping
32
Autism - 86% of children with _________ intellectual disability are autistic and 42% of _________ affected children are autistic
- profound | - severely
33
Autism - _________ or impaired language development, often repeat what others say, obsessive interest in facts, prefer to be _________, treat other people as objects (walk over them)
- Mute | - alone
34
Autism - Mute or impaired language development, often _________ what others say, obsessive interest in facts, prefer to be alone, treat other people as _________ (walk over them)
- repeat | - objects
35
Autistic individuals do not _________ with other people, infer what others are thinking (theory of mind), and do not form strong _________ bonds – could be due to a malfunction in the activity of mirror neurons
- empathize | - social
36
Autistic individuals do not empathize with other people, infer what others are _________ (theory of mind), and do not form strong social bonds – could be due to a malfunction in the activity of _________ neurons
- thinking | - mirror
37
Autistic individuals do not show _________ activity when watching other people
mirror neuron
38
Mirror neurons are active when we perform a task but also when we see _________ perform the same task
someone else
39
Mirror neurons are important for understanding other people, identifying with them, and imitating them – mentally _________ other people’s behavior may give us insight to their thoughts
mimicking
40
Autism - Apparent increase in incidence of autism likely due to increased _________ of disorder rather than actually increase in cases
diagnosis
41
_________ – very similar to autism but language, cognitive development and self-help skills more normal
Asperger’s syndrome
42
Asperger’s syndrome – very similar to autism but language, _________ development and self-help skills more _________
- cognitive | - normal
43
Autistic savants – have isolated _________ abilities but overall functioning is _________
- exceptional | - impaired
44
Autism – Biological Bases Across individuals, no consistent _________ in brain abnormalities
pattern
45
Autism – Biological Bases Anomalies in brain stem, _________, and temporal lobes
cerebellum
46
Autism – Biological Bases Unusual patterns and _________ of brain activity
timing
47
Autism – Biological Bases Controversy over role of vaccines containing mercury in autism - Correlation between _________ of vaccines and onset of autism - Evidence does not support a link between _________ and autism
- timing | - vaccines
48
Autism – Biological Bases Controversy over role of vaccines containing mercury in autism - Correlation between timing of vaccines and onset of _________ - Evidence _________ support a link between vaccines and autism
- autism | - does not
49
Autism – Biological Bases Autoimmune reaction- Autistic children have brain _________ that affect neurons and myelin – autopsies of autistic individuals have found increased levels of _________ and microglia in the brain suggesting increased immune activity
- autoantibodies | - astroglia
50
Autism – Biological Bases Autoimmune reaction- Autistic children have brain autoantibodies that affect neurons and _________ – autopsies of autistic individuals have found increased levels of astroglia and microglia in the brain suggesting _________ immune activity
- myelin | - increased
51
Autism – Biological Bases Levels of serotonin- Increasing _________ activity (e.g., antidepressant drugs) improve some autistic symptoms in adults
serotonin
52
Autism – Biological Bases Levels of oxytocin are _________ than normal - Intravenous infusions of oxytocin reduced the number and severity of repetitive behavior - May improve _________ interaction
- lower | - social
53
Autism – Biological Bases Levels of oxytocin are lower than normal - Intravenous infusions of _________ reduced the number and severity of _________ behavior - May improve social interaction
- oxytocin | - repetitive
54
Autism – Biological Bases Genetic influences- Risk of autism in an identical twin is ___% but many twins without autism still have social and cognitive _________
- 60 | - impairments
55
Autism – Biological Bases Genetic influences- _________ twins have a 10% concordance
Fraternal
56
Autism – Biological Bases Genetic influences- Autism is likely to be _________ so severity depends on how many genes inherited – _________ also show mild social and cognitive abnormalities
- polygenic | - parents
57
- LAST CARD - Autism – Biological Bases ``` Genetic influences- More common (4 times) in _________ – may be linked to ___ chromosome ```
- males | - X