Exam 2 - 2/9 Flashcards
_________ - Small and medium blood vessel don’t get blood to hands, fingers, toes
Buerger’s Disease
A drug is a _________ that on entering the body changes the body or its _________
- substance
- functioning
A drug is a substance that on entering the _________ changes the _________ or its functioning
- body
- body
_________ mimics the effect of a neurotransmitter
-agonist
_________ sits on neurotransmitter receptors blocking the effects of the neurotransmitter
antagonist
An antagonist sits on neurotransmitter receptors _________ the effects of the neurotransmitter
blocking
An agonist mimics the effect of a _________
neurotransmitter
Drugs can alter neurotransmission by:
-Acting as _________ or antagonists
-agonists
Drugs can alter neurotransmission by:
-Increasing or decreasing the amount of _________ released
-neurotransmitter
Drugs can alter neurotransmission by:
-Blocking the _________ of neurotransmitter into the _________ neuron
- re-uptake
- presynaptic
Psychoactive drugs – those that have _________ effects
psychological
Psychoactive drugs – those that have psychological effects (e.g., _________ relief, _________ )
- anxiety
- hallucinations
-Categories of Psychoactive Drugs-
_________ -
Cocaine, amphetamine, ecstasy (MDMA), caffeine, nicotine
Stimulants
-Categories of Psychoactive Drugs-
Stimulants-
_________, amphetamine, ecstasy (MDMA), caffeine, _________
- Cocaine
- nicotine
-Categories of Psychoactive Drugs-
Stimulants-
Cocaine, _________, ecstasy (MDMA), _________ , nicotine
- amphetamine
- caffeine
-Categories of Psychoactive Drugs-
_________ -
Alcohol
Sedatives/depressants
-Categories of Psychoactive Drugs-
_________ -
Morphine, heroin
Opiates
-Categories of Psychoactive Drugs-
Opiates-
Morphine, _________
heroin
-Categories of Psychoactive Drugs-
_________-
LSD, psilocybin, (ecstasy)
Hallucinogens (Psychedelics)
Drugs are categorized according to their _________ action
predominant
_________ drugs increase excitement, alertness, motor activity and elevate mood
Stimulant
Stimulant drugs increase excitement, alertness, _________ activity and _________ mood
- motor
- elevate
Stimulant drugs increase excitement, alertness, motor activity and elevate mood
Examples: _________, cocaine, methylphenidate, _________, nicotine
- amphetamines
- MDMA (Ecstasy)
-Stimulants: _________ -
Elevation of mood and increased alertness
Cocaine
-Stimulants: Cocaine-
From South American _________ plant
-Leaves chewed or used to make tea in Bolivia, Columbia, and Peru – increases _________ , sense of well-being
- coca
- endurance
-Stimulants: Cocaine-
From South American coca plant
-Leaves chewed or used to make tea in Bolivia, Columbia, and Peru – increases endurance, sense of _________
-well-being
_________ - ritalin
methylphenidate
_________ - ritalin
methylphenidate
-Stimulants: _________ -
Euphoria, appetite suppressant, increased alertness, decreases fatigue
Cocaine
-Stimulants: Cocaine-
Euphoria, appetite _________, increased alertness, decreases _________
- suppressant
- fatigue
-Stimulants: _________ -
Snorted as a powder, injected as a solution, or smoked (freebase, crack) – fast onset increases addiction potential
-Cocaine
-Stimulants: Cocaine-
Snorted as a powder, _________ as a solution, or smoked (freebase, crack) – fast onset increases _________ potential
- injected
- addiction
-Stimulants: Cocaine-
Mechanism of action:
Blocks _________ transporters on presynaptic terminals increasing the amount of _________ in the synaptic cleft
- dopamine
- dopamine
-Stimulants: Cocaine-
Mechanism of action:
_________ dopamine transporters on presynaptic terminals increasing the amount of dopamine in the _________
- Blocks
- synaptic cleft
Methylphenidate (Ritalin) used to treat ADHD also blocks _________ of dopamine
-reuptake
Methylphenidate (_________) used to treat ADHD also blocks reuptake of _________
- Ritalin
- dopamine
-Stimulants: Cocaine-
Mechanism of action:
Blocks reuptake of _________
serotonin
-Stimulants: Cocaine-
Mechanism of action:
- Reduces _________ inhibition of lower brain structures
- _________
- cortical
- Euphoria
-Stimulants: Cocaine-
Mechanism of action:
- Reduces cortical inhibition of _________ brain structures
- -Euphoria
-lower
-Stimulants: Cocaine-
Withdrawal is _________
-mild
-Stimulants: Cocaine-
Withdrawal is mild
- _________ (lack of pleasure), anxiety, lack of motivation
Anhedonia
-Stimulants: Cocaine-
Withdrawal is mild
-Anhedonia (lack of pleasure), _________, lack of _________
- anxiety
- motivation
-Stimulants: Cocaine-
Withdrawal is mild
-Tolerance to _________ effects causes escalation of _________
- euphoric
- dose
-Stimulants: Cocaine-
Withdrawal is mild
Long-term use can cause stimulant _________ (sensitization), _________
- psychosis
- seizures
Stimulants: _________
Synthetic drug with similar effects to those of cocaine
Amphetamine
Stimulants: Amphetamine
_________ , increased confidence and concentration, decreased _________
- Euphoria
- appetite
Stimulants: _________
Euphoria, increased confidence and concentration, decreased appetite
Amphetamine
Stimulants: Amphetamine
Euphoria, increased _________ and _________ , decreased appetite
- confidence
- concentration
Stimulants: _________
Used to treat narcolepsy
Amphetamine
Stimulants: _________
Methamphetamine
Amphetamine
Stimulants: Amphetamine
_________ -
Meth, speed, crank, crystal
Freebase = ice (smokable)
Methamphetamine
Stimulants: Amphetamine
Methamphetamine -
Meth, speed, _________ , crystal
Freebase = _________ (smokable)
- crank
- ice
XXXXXXXXXX
Meth, like other stimulants, suppresses _________ and can lead to _________ due to long periods without eating.
-appetite
undernourishment
XXXXXXXXXX
Meth Mouth” is caused by several factors; tooth enamel is dissolved by the harsh _________ of the drug, the blood vessels contained in healthy gums and teeth shrink, increasing the rate of decay, the production of saliva _________ , allowing harmful acids to further damage the mouth, cravings for sugary foods increases with meth use,
- chemicals
- diminishes
XXXXXXXXXX
Meth Mouth” is caused by several factors; tooth enamel is dissolved by the harsh chemicals of the drug, the blood vessels contained in healthy gums and teeth _________, increasing the rate of decay, the production of saliva diminishes, allowing harmful acids to further damage the mouth, cravings for sugary foods _________ with meth use,
- shrink
- increases
-Stimulants: Amphetamine-
Also produces stimulant _________
psychosis
Anhedonia (lack of _________),
pleasure
-Stimulants: Amphetamine-
Also produces stimulant psychosis
–Symptoms of paranoid _________
schizophrenia
-Stimulants: Amphetamine-
Mechanism of action:
-Increases the release of _________ and dopamine
norepinephrine
-Stimulants: Amphetamine-
Mechanism of action:
-Increases the release of norepinephrine and _________
dopamine
-Stimulants: _________ -
Mechanism of action:
Increases the release of norepinephrine and dopamine
Amphetamine
Cocaine is a _________
vasoconstrictor
Cocaine blocks the _________ channels - creating a local _________
- sodium
- anesthetic
-Stimulants: Amphetamine-
Mechanism of action:
- Increases the release of norepinephrine and dopamine
- _________ depletion
Dopamine
-Stimulants: _________ -
Addictive substance in tobacco
Nicotine
-Stimulants: _________ -
Smoked (stimulant/sedative – dose dependent), chewed, inhaled (snuff, sedative)
Nicotine
-Stimulants: Nicotine-
Smoked (stimulant/sedative – dose dependent), _________ , inhaled (snuff, _________ )
- chewed
- sedative
-Stimulants: Nicotine-
Large doses - nausea, _________, headaches, convulsions and _________
- vomiting
- death
-Stimulants: _________ -
Large doses - nausea, vomiting, headaches, convulsions and death
Nicotine
-Stimulants: Nicotine-
Large doses - _________ , vomiting, headaches, _________ and death
- nausea
- convulsions
-Stimulants: _________ -
Withdrawal – nervousness, anxiety, headaches
Nicotine
-Stimulants: Nicotine-
Withdrawal – _________, anxiety, _________
- nervousness
- headaches
-Stimulants: Nicotine-
_________ use – increased health risks from tobacco _________
- Continuous
- smoke
-Stimulants: _________ -
Coughing, bronchitis, emphysema, cancer
Greatest number of preventable deaths
Nicotine
- LAST CARD -
- Stimulants: Nicotine-
Coughing, bronchitis, _________, cancer
Greatest number of _________ deaths
- emphysema
- preventable