Exam 3: Viruses Flashcards

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1
Q
  • gram pos.
  • rod shaped
  • anaerobic
A

clostridium tetani

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2
Q
  • spore forming bacteria

- description of disease by hippocrates exists from at least far back as 5BC

A

clostridium tetani

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3
Q

clostridium tetani produces a toxin called

A

tetanospasmin

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4
Q

when it comes to clostridium tetani, it has a potent neuotoxin (tetanospasmin) that is similar to

A

stychnine

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5
Q

tetanospasmin is the 2nd highest toxin known next to __ toxin from another Clostrium sp.

A

botulinum

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6
Q

tetanospasmin can lead to ___ failure

A

respiratory

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7
Q

clostridium tetani migrates through the __ __ system and then is transported to the __ ___ system

A

peripheral nervous, central nervous

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8
Q

clostridium tetani causes generalized contracions of the __ and __ musculature

A

agonist, antagonist

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9
Q

tetanic spasms can occur in a distinctive form called __ and be sufficiently severe to fracture long bones

A

opisthotonos

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10
Q

vaccines against tetanospasmin needs to be vaccinated every __ years

A

10

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11
Q

member of the orthmoyxoviridae family

A

influenza

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12
Q
  • enveloped virus with 7 or 8 (-) ssRNA strands

- different strains are identified by 2 envelope proteins

A

influenza

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13
Q

type A influenza infects…? how many segments?

A

avian and mammals. 8 RNA segments

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14
Q

type B influenza infects..? how many segments?

A

humans and seals. 8 RNA segments

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15
Q

type C influenza infects..? how many segments?

A

humans and pigs. 7 RNA segments

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16
Q

major type A epidemics:

A

H1N1, H2N2, H3N2, H5N1,H5N7

17
Q

caused spanish flu (1918) and swine flu (2009)

A

H1N1

18
Q

caused Asian flu (1957)

A

H2N2

19
Q

H3N2 caused what kind of flu?

A

Hong Kong flu

20
Q

H5N1 caused what kind of flu?

A

bird flu

21
Q

___ primarily an avian virus but has a very high mortality rate in humans (70%)

A

H5N1

22
Q

H1N1 may have started in more than one location:

A

Haskell county, Kansas, Brest, France

23
Q

bunyaviridae family

A

hantavirus

24
Q

(-)ssRNA genome segmented

  • 3 RNA strands
  • ambisense
A

hantavirus

25
Q

single stranded genome that contains both positive sense and negative sense

A

hantavirus

26
Q

all bunyavinidae family members are transmitted by arthropods except for

A

hantavirus

27
Q

member of the paramxoviridae family

A

measles

28
Q

single -stranded, neg sense, enveloped RNA virus (-ssRNA)

A

measles

29
Q

___ are the only natural hosts of the virus in measles

A

humans

30
Q

mutation rate of the virus indicates the measles virus emerged from rinderpest virus as __ disease between 1100 to 1200 AD

A

zoonotic

31
Q

who developed vaccine for measles

A

Maurice Hilleman

32
Q

measles attack what cells?

A

immune