Exam 3 - Spinal Cord Flashcards
The spinal cord begins as a continuation of the medulla oblongata (the most inferior portion of the brain stem) extending
from the foramen magnum of the occipital bone to its termination as the conus medullaris between L1 - L2.
I.E. spine runs from Medulla to L2 (conus medullaris)
Where does the spinal cord terminate?
conus medullaris between L1 - L2
What surrounds the spinal cord?
The spinal meninges (singular = meninx) surround the spinal cord, and are continuous with the cranial meninges, which encircle the brain
The three meninges, from outermost inward, are:
Dura mater (DOO-ra MĀ-ter) Arachnoid mater Pia mater (PĒ-a MĀ-ter)
The arachnoid is continuous with the…
arachnoid mater of the brain
Between the dura mater and the arachnoid mater is the______, which contains interstitial fluid
thin subdural space
the subdural space is full of?
interstitial fluid
Contains blood vessels that supply oxygen and nutrients to the spinal cord.
Pia mater
Is a thin transparent connective tissue layer that adheres to the surface of the spinal cord and brain
Pia mater
Between the arachnoid mater and the pia mater is a space filled with cerebrospinal fluid called the…
subarachnoid space
Membranous, thickened extensions of the pia mater that project laterally and fuse with arachnoid mater and inner surface of dura mater
Denticulate ligaments
Suspend the spinal cord within its dural sheath, protecting it against sudden displacement
Denticulate ligaments
Delicate strands of tissue emanating from the arachnoid mater
Arachnoid trabeculae
Span the subarachnoid space, connecting the arachnoid and the pia
Arachnoid trabeculae
Look at picture of slide 9… remember what he said about the arachnoid villae being near the dural sinuses***
Good job
In adults the spinal cord extends from the medulla oblongata (the inferior part of the brain) to the ____ of the second lumbar vertebra
superior border
The cervical enlargement and lumbar enlargement accommodate nerves to and from the…
upper and lower limbs, respectively
Inferior to the lumbar enlargement the spinal cord tapers to a conical-shaped portion termed the conus medullaris, which in adults ends at the level of…
the IV disc between vertebrae L1 & L2
The _______ is an extension of the pia mater that arises from the conus medullaris to anchor the spinal cord to the coccyx
filum terminale
Nerves that arise from the inferior part of the spinal cord do not immediately leave the vertebral column, but rather continue in the vertebral canal in fine strands collectively termed the ….
cauda equina (horse’s tail)
Lumbar puncture AKA
spinal tap
Lumbar puncture AKA spinal tap
After administration of a local anesthetic, long needle is inserted into the ____
subarachnoid space
Lumbar puncture AKA spinal tap
Patient lies on side with vertebral column flexed (similar to fetal position), which increases distance between….
spinous process of the vertebrae
Lumbar puncture AKA spinal tap
Uses of spinal tap?
Withdraw CSF for diagnostic purposes Introduce antibiotics Introduce contrast media **** Introduce anesthetics Administer chemotherapy Measure CSF pressure
Spinal nerves are the paths of communication between the spinal cord and…
the nerves innervating specific regions of the body
Spinal Nerves:
___ bundles of axons connect each spinal nerve to a segment of the cord
-Each bundle is called a ___, which in turn is composed of smaller bundles of axons called rootlets
-The roots are The posterior (or dorsal) root The anterior (or ventral) root
Two
root
Spinal Nerves:
-Each bundle is called a root, which in turn is composed of smaller bundles of axons called ____
-The roots are:
Two types
rootlets
The posterior (or dorsal) root The anterior (or ventral) root
Spinal Nerves:
-Each bundle is called a root, which in turn is composed of smaller bundles of axons called ____
-The roots are:
Two types or pathways?
rootlets
The posterior (or dorsal) root The anterior (or ventral) root
External Cord Anatomy
Each posterior root has a swelling, the posterior (dorsal) root ganglion, which contains….
the cell bodies of sensory neurons.
External Cord Anatomy
The anterior (ventral) root and rootlets contain axons of motor neurons, which conduct nerve impulses from…
the CNS to effectors (muscles and glands).
the bump on the external cords means what?
if it has a bump it is full of cell bodies therefore it is a POSTERIOR (DORSAL) root ganglion
The ___ matter of the spinal cord is shaped like the letter H, or a butterfly, and is surrounded by white matter
The gray ____ forms the crossbar of the H
gray
commissure
______ contain cell bodies of somatic motor neurons and motor nuclei that provide nerve impulses for the contraction of skeletal muscles.
Anterior horns
______ contain somatic and autonomic sensory nuclei. The gray commissure connects gray matter of the right and left sides.
Posterior gray horns
The ______extends the length of the spinal cord, and is continuous with the fourth ventricle in the medulla oblongata of the brain
central canal
The central canal extends the length of the spinal cord, and is continuous with the ____ in the medulla oblongata of the brain
fourth ventricle
Anterior to the gray commissure is the anterior (ventral) white commissure, which connects….
the white matter of the right and left sides of the spinal cord
Lateral gray horns are present only in….
the thoracic and upper lumbar, (T1 – L2 or T1 – L3) and sacral (S2 – S4) segments of the spinal cord.
______ contain cell bodies of autonomic motor neurons that regulate activity of smooth muscle, cardiac muscle, and glands.
Lateral gray horns
____ receives and integrates incoming and outgoing information
Gray matter
Poliomyelitis is caused by the poliovirus
Onset is marked by fever, severe headache, stiff neck and back, deep muscle pain and weakness
Polio
The virus produces damage and paralysis by destroying cell bodies of motor neurons in the anterior horn of the spinal cord and in nuclei of cranial nerves. It can cause death from respiratory or heart failure if the virus invades neurons in centers that control breathing and heart function
Polio vaccines have virtually eradicated polio in the U.S., but it still exists in other parts of the world
Polio
Polio damages what and where?
How can it cause death?
The virus produces damage and paralysis by destroying cell bodies of motor neurons in the anterior horn of the spinal cord and in nuclei of cranial nerves.
It can cause death from respiratory or heart failure if the virus invades neurons in centers that control breathing and heart function
The anterior and posterior gray horns divide the white matter into three broad areas called columns:
Anterior (ventral) white columns
Posterior (dorsal) white columns
Lateral white columns
Bundles of myelinated axons, called ____, have a common origin or destination, and carry similar information up or down the spinal cord
tracts
____ comprise axons that conduct nerve impulses toward the brain
Sensory (ascending) tracts
_____ carry nerve impulses down the spinal cord
Motor (descending) tracts
____ matter tracts ascend to or descend from the brain.
____ matter processes information input and output.
White
Gray
____ matter tracts ascend to or descend from the brain.
____ matter processes information input and output.
White: ascend or descend
Gray: input / output
Spinal nerves and the nerves that branch from them are part of the ______
They connect the _____ to sensory receptors, muscles, and glands in all parts of the body—i.e. spinal nerves connect the PNS to the CNS
There are ___ pairs of spinal nerves
peripheral nervous system
central nervous system
31
Spinal nerves are named and numbered according to….
the region and level of the vertebral column from which they emerge
Naming Spinal Nerves:
The first cervical pair emerges between the….
All other spinal nerves emerge through _____ between adjoining vertebrae
occipital bone and the atlas
intervertebral foramina
Spinal Nerves are named in sequence:
List # of pairs and their names
8 pairs of cervical nerves are named C1 – C8
12 pairs of thoracic nerves named T1 – T12
5 pairs of lumbar nerves named L1 – L5
5 pairs of sacral nerves named S1 – S5
1 pair of coccygeal nerves named Co1
Most spinal nerves exit ___ to the vertebra of the same number, the exception being …. ?
inferior
Exception: cervical nerves due to the fact that C1 exits superior to the atlas (which is the first cervical vertebra)
Spinal nerve names correlate with exit from vertebral column:
Spinal nerves do not necessarily exit the spinal cord in the same plane as….
Illustrated: spinal nerve L1 exits the vertebral column inferior to L1 vertebra, but it exits the spinal cord on a plane between T11 & T12 vertebrae
their corresponding vertebrae
Look at L1 on slide 32 of ppt
Spinal nerve names correlate with exit from vertebral column:
During early childhood, both the spinal cord and vertebral column grow longer as part of overall growth
Spinal cord elongation stops about age ____, but _____ growth continues
4 or 5 years
vertebral column
Spinal nerve names correlate with exit from vertebral column :
The consequence is the observed ____, and the fact that in adults, the spinal cord does not…
offset
extend the entire length of the vertebral column
Spinal nerve names correlate with exit from vertebral column :
The resulting cauda equina comprises roots of the….
lower lumbar, sacral, and coccygeal nerves
Several rootlets emerge from the dorsal and ventral surfaces of the spinal cord
The rootlets converge to form the….
The dorsal and ventral nerve roots unite at…
Each spinal nerve divides almost immediately into….
dorsal and ventral roots of the spinal nerves
their points of exit from the vertebral canal to form a spinal nerve
a dorsal primary ramus and a ventral primary ramus
The rootlets converge to form the….
dorsal and ventral roots of the spinal nerves
The dorsal and ventral nerve roots unite at…
their points of exit from the vertebral canal to form a spinal nerve
Each spinal nerve divides almost immediately into….
a dorsal primary ramus and a ventral primary ramus
Spinal nerves technically comprise only that brief interval between union of the dorsal and ventral roots, and subsequent division into
dorsal and ventral rami
Spinal nerves technically comprise only that brief interval between union of the ____, and subsequent division into dorsal and ventral rami
dorsal and ventral roots
Individual axons (myelinated or unmyelinated) are covered by an _____
Groups of axons comprise a ____
Each fascicle is wrapped in ____
The entire nerve is covered by an _____
endoneurium
fascicle
perineurium
epineurium
The _______ is a white matter motor pathway starting at the cerebral cortex that terminates on lower motor neurons and interneurons in the spinal cord, controlling movements of the limbs and trunk.
corticospinal tract
Each nerve divides into several branches just after passing through its ____
Each branch is a _____
Rami are the terminal branches of ____
intervertebral foramen
ramus (= branch; rami is plural)
spinal nerves
____ innervates deep muscles and skin of the dorsal surface of the trunk
The posterior (dorsal) ramus
_______ serves muscles and structures of the upper and lower limbs and the skin of the lateral and ventral surfaces of the trunk
The anterior (ventral) ramus
The ____ branch of each spinal nerve reenters the vertebral canal to supply the vertebrae and associated structures
meningeal
Other branches form the ____ and contribute to the trunk ganglia of the autonomic nervous system
rami communicantes
Except for most thoracic nerves, the ____ of spinal nerves do not go directly to the body structures they supply
Rather, they form networks on both the left and right sides of the body by joining with….
This network of axons is called a ____
anterior rami
…other axons from anterior rami of adjacent nerves
plexus (meaning braid, or network)
Principal plexuses:
Cervical plexus
Brachial plexus
Lumbar plexus
Sacral plexus
(Also, a smaller coccygeal plexus)
Nerves emerge from the ____
The nerve names are often descriptive of the general regions they serve, or the course they take
plexuses
Each of the nerves may have several branches, each named for…
the specific structure they innervate
There is no “thoracic plexus” corresponding to the cervical plexus, lumbar plexus, etc.
True
______ of spinal nerves T2 – T12 are called intercostal nerves. Another name for them is thoracic nerves.
Anterior rami