Exam 3: Physiology of Liver & Pancreas Flashcards
How does blood flow from the portal vein through the liver?
Portal vein–>Sinusoids–>Central vein–>Hepatic veins
How does blood flow from the hepatic artery through the liver?
Hepatic artery–>Sinusoids–>Central vein–>Hepatic veins
What does the Space of Disse flow into?
Lymph ducts
What effect does cirrhosis have on blood flow of the liver?
Increases resistance to blood flow
What is the normal volume of the liver?
450ml (10% of blood volume in body)
T/F: Liver cannot store blood or supply blood in times of excess or need.
False, it can do both
Hepatic sinusoids are highly permeable to _____.
Proteins
Higher than normal pressure in hepatic veins and large fluid build up in abdominal cavity is called…?
Ascites
Which vitamins are stored in the liver?
A, D, B12
What is the major pigment in bile?
Bilirubin
Where is urobilinogen created and where can it go?
Intestines.Out in feces as stercobilin or back to liver & circulation again
What disease is caused by bilirubin in the extracellular matrix?
Jaundice
Increased hemolysis & obstruction of bile ducts or damage to liver are causes of what?
Jaundice
What do Alpha cells in the pancreas secrete?
Glucagon
What do Beta cells in the pancreas secrete?
Insulin & Amylin