Exam 3 Lecture 4 Flashcards
Meth increases what NTM
Glutamate
Pleasure Reward Center NTM?
*Function
*Parkinson’s
Dopamine
*Inhibit Motor System
*Decreased dopamine = increased motor system [shakes]
How many ACh to open? How many do we have at that receptor?
2, 3
CO2 Influence: Hyperventilate
More CO2 blown off = more alkalotic = less free Ca++ = increased CNS activitiy
Alkalotic: Albumin Plasma Protein Binding
Less P+ inside, so more Ca++ bind inside Albumin; less free Ca++ = increased CNS Activity
Formula Given per Lecture with Bicarb
H+ HCO3- = H2HCO3 = CO2 + H2O
NDMR Onset and Duration
Few minutes; may last minutes - hours
More Important Muscles = ? block
*why
More important muscles = harder to paralyze; more receptors and more NTM than what is needed
How to increase ACh?
*S/S
AChesterase Inhibitor
*Bradycardia by blocking vagus nerve
*increased secretions
The Ulnar Nerve innervates what muscle?
Adductor Pollicis
Where can fetal/immature nACh-R be located
*why is this bad for SUX
*What Ion can come in with Sux
NMJ and Postjunctional area
*Bad for SUX as more K+ is released
*Ca++
2 Main Inhibitory NTM of the Spinal Cord
GABA and Glycine
Tetatnic
High Frequency in short period of time >4 twitches/impulses
Outermost Part of Skeletal Muscle where Immature nACh-R are place in a Neuro injury?
Postjunctional Area
What is a response from TO4 on the Ulnar Nerve?
Thumb moves forward and pinky twitches
TOF: All twitch disappear %
90 to 95%
Post-Tetanic Count [PTC]
After tetanic stimulus, counting to see how muscle reacts
Supramaximal Stimulus
Strong enough depolarization to recruit all of the motor neurons in the underlying nerves to get best result in TO4
What nerves do the Phrenic Nerve connect to the Diaphragm
C3, C4, C5
Which nerve connects C3, C4, and C4 nerves to the diaphragm?
Phrenic Nerve
How is Benadryl categorized per lecture
Anti-Histamine and mACh-R antagonist