Exam 3 (chapter 12 part 4) Flashcards

1
Q

high intensity exercises uses ____________ fibers, causes a buildup of ____________, strong contractions cause compression of ______________ _______________, causes neuromuscular ___________, altered __________ activity, and recovery happens within ___________ to hours

A

glycolytic, lactate, blood vessels, fatigue, enzyme, minutes

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2
Q

neuromuscular fatigue is due to the depletion of _________________

A

acetylcholine

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3
Q
  • lacks striations
  • found in internal organs and blood vessels
  • under involuntary control by the ANS
  • spindle shaped
  • small in size
  • contains actin and myosin
  • does not have sarcomeres
  • dense bodies
A

smooth muscle

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4
Q

Align actin/myosin filaments in smooth muscles

A

dense bodies

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5
Q

does smooth muscle have sarcomeres?

A

no, no striations

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6
Q

does smooth muscle have actin AND myosin?

A

yes

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7
Q

do lungs have much smooth muscle? if not, what in the respiratory system does?

A

no, Bronchi

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8
Q

actin and myosin are ______________ in smooth muscle than in skeletal muscle
- myosin heads whole length giving a longer range of contraction

A

longer

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9
Q

in smooth muscle, myosin heads are along the whole length, what does this give you?

A

longer range of contraction

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10
Q

what are the 6 steps of smooth muscle excitation contraction coupling?

A
  1. Ca++ comes in from ECF through voltage gated channels,
  2. Ca++ triggers release of Ca++ from SR,
  3. Ca++ binds to calmodulin,
  4. Ca++calmodulin activates MLCK,
  5. MLCK phosphorylates myosin,
  6. cross bridge cycling
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11
Q

kinase that phosphorylates the myosin head in smooth muscule

A

MLCK

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12
Q

to relax smooth muscle:

  • phosphatase removes phosphate from ____________
  • _____________ is removed from cytoplasm
A

Myosin,

Ca2+

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13
Q

what are the 2 ways that Ca++ is removed from the cytoplasm in smooth muscle?

A

Ca++ ATPase, Ca++/Na+ countertransport

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14
Q

smooth muscle is innervated by the _______________ nervous system

A

autonomic (sympathetic and/or parasympathetic)

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15
Q

is smooth muscle excitatory or inhibitory?

A

both

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16
Q
  • striated due to sarcomeres
  • troponin-tropomyosin regulation
  • gap junctions
  • pacemaker cells
  • innervated by ANS
  • Ca++ comes from ECF and SR
  • action potential lasts as long as tension
  • no summation
A

cardiac muscle

17
Q

smooth muscle can be connected by _________ _____________

A

gap junctions

18
Q

can cardiac muscle stimuli be summed?

A

no (long refractory period)

19
Q

what is smooth muscle regulated by?

A

Ca++

20
Q

what are skeletal and cardiac contraction muscle regulated by?

A

troponin-tropomyosin

21
Q

troponin-tropomyosin are leated to which types of muscle

A

cardiac and skeletal

22
Q

does cardiac muscle have gap junctions?

A

yes

23
Q

skeletal muscle:

  • striations?
  • actin and myosin?
  • level of control?
  • neural input?
  • neuroeffector junction?
  • hormonal control?
  • source of Ca++?
  • regulatory protein that binds to Ca++?
  • gap junctions?
  • pacemaker activity?
  • myosin ATPase activity?
  • recruitment?
A

skeletal muscle:

  • striations: yes
  • actin and myosin: yes
  • level of control: voluntary
  • neural input: somatic
  • neuroeffector junction: neuromuscular junction
  • hormonal control: none
  • source of Ca++: SR
  • regulatory protein that binds to Ca++: troponin
  • gap junctions: no
  • pacemaker activity: no
  • myosin ATPase activity: fastest
  • recruitment: yes
24
Q

smooth muscle:

  • striations?
  • actin and myosin?
  • level of control? (voluntary or involuntary)
  • neural input?
  • neuroeffector junction?
  • hormonal control?
  • source of Ca++?
  • regulatory protein that binds to Ca++?
  • gap junctions?
  • pacemaker activity?
  • myosin ATPase activity?
  • recruitment?
A

smooth muscle:

  • striations: no
  • actin and myosin: yes
  • level of control? (voluntary or involuntary): involuntary
  • neural input: N/A
  • neuroeffector junction: several
  • hormonal control: SR and ECF
  • source of Ca++: Calmodulin
  • regulatory protein that binds to Ca++: sometimes
  • gap junctions: sometimes
  • pacemaker activity: no
  • myosin ATPase activity: slowest
  • recruitment: sometimes
25
Q

cardiac muscle:

  • striations?
  • actin and myosin?
  • level of control?
  • neural input?
  • neuroeffector junction?
  • hormonal control?
  • source of Ca++?
  • regulatory protein that binds to Ca++?
  • gap junctions?
  • pacemaker activity?
  • myosin ATPase activity?
  • recruitment?
A

cardiac muscle:

  • striations: yes
  • actin and myosin: yes
  • level of control: involuntary
  • neural input: N/A
  • neuroeffector junction: epinephrine
  • hormonal control: SR and ECF
  • source of Ca++: Troponin
  • regulatory protein that binds to Ca++: yes
  • gap junctions: yes
  • pacemaker activity: yes
  • recruitment: no
26
Q

what are the 2 hormones that affect skeletal muscle development? can they affect contraction?

A

growth hormone, testosterone, no

27
Q

does smooth muscle have fast or slow myosin ATPase activity?

A

slow