Exam 3: Calcivirus Flashcards
How do you morphologically characterize a calcivirus?
Virions have a capsid and are non-enveloped
Round capsid/nucleocapsid with icosahedral symmetry
Capsomere is clearly visible
Capsid has 32 cup-shaped depressions
What are the genomic characteristics of calcivirus?
Genome is not segmented and consists of a single molecule of linear positive-sense single-stranded RNA
By itlsef, genomic nucleid acid is infectious
Genomes code for one major structural capsid protein (VP1) and a minor capsid protein (VP2) and a large polyprotein (NS)
What is San Miguel sea lion virus synonymous with?
It is related to vesicular exanthema of swine viruses morphologically and antigenically
What viruses are in the genera Vesivirus?
San Miguel sealion viruses
Vesicular exanthema of swine viruses
Feline calcivirus
What are hosts of San Miguel sealion viruses?
Sea lion
Pinnipeds
What is the host of vesicular exanthema of swine viruses?
Swine
What is the host of feline calcivirus?
Feline
What is the disease associated with San Miguel sealion viruses?
Vesicular, neonatal hemorrhagic syndrome
What is the disease associated with vesicular exanthema of swine viruses?
Vesicular, purpura hemorrhagica in aborted piglets
What is the disease associated with feline calcivirus?
Oral ulcers
URT disease
Pneumonia
Arthritis, hemorrhagica, and enteritis are rare
What is the virus in the Lagovirus genera?
Rabbit calcivirus disease
What is the host of rabbit calcivirus dsease?
European rabbit
What is the disease associated with rabbit calcivirus disease?
Hemorrhagic, systemic, and hepatotropic
What is the virus in the Norovirus genera?
Bovine enteric calciviruses
What is the host of bovine enteric calciviruses?
Bovine, European