Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Infectious Agents II > Exam 2: Coronaviridae > Flashcards

Exam 2: Coronaviridae Flashcards

1
Q

What are the properties of coronaviruses?

A

Linear plus sense ssRNA genome
75-160 nm
Envelop with large widely spaced, club-shaped peplomers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Where do coronaviruses replicate?

A

Cytoplasm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are coronavirus virions released by?

A

Exocytosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What are the 4 structural proteins that make up coronaviruses?

A

Peplomer glycoprotein S
Transmembrane glycoprotein M
Nucleocapsid phosphoprotein N
Hemagglutintin plus acetylesterase activities, HE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What are the viruses in coronavirus antigenic group I (mammalian)?

A

Human coronavirus 229E
Transmissible gastroenteritis virus of swine
Feline infectious peritonitis virus
Canine coronavirus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What disease is associated with human coronavirus 229E?

A

Common cold

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What disease is associated with transmissible gastroenteritis virus of swine?

A

Gastroenteritis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What disease is associated with feline infectious peritonitis virus?

A 
Peritonitis
Pneumonia
Meningoencephalitis
Panophthalmitis
Wasting
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What disease is associated with canine coronavirus?

A

Enteritis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What are the viruses in antigenic group II (mammalian)?

A

Human coronavirus OC43
Mouse hepatitis virus
Bovine coronavirus
Porcine hemagglutinating encephalomyelitis virus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What disease is associated with human coronavirus OC43?

A

Common cold

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What disease is associated with mouse hepatitis virus?

A

Hepatitis
Encephalomyelitis
Enteritis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What disease is associated with bovine coronavirus?

A

Gastroenteritis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What disease is associated with porcine hemagglutinating encephalomyelitis virus?

A

Vomiting
Wasting
Encephalomyelitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What are the viruses in antigenic group III (avian)?

A

Infectious bronchitis virus of chickens

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What are the diseases associated with infectious bronchitis virus of chickens?

A

Tracheobronchitis

Nephritis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What are the viruses in antigenic group IV (avian)?

A

Bluecomb disease virus of turkeys

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What disease is associated with bluecomb disease virus of turkeys?

A

Enteritis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

When does transmissible gastroenteritis (TGE) of swine occur?

A

Winter months

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

What is transmissible gastroenterits (TGE) of swine characterized by?

A

Vomiting and profuse diarrhea

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

What does TGE cause in piglets?

A

High mortality

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

What is the efficacy of vaccines for TGE like?

A

Limited

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

When does TGE occur?

A

Farrowing time

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

What is the incubation time for TGE?

A

1-3 days

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

What are the sign of TGE in infected piglets?

A

Show vomiting, watery diarrhea, and rapid loss of weight

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

How quickly do pigs less than 7 days of age with TGE die?

A

Generally within 2 to 7 days

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

What happens to piglets infected with TGE that are more than 3 weeks of age?

A

They usually live, but weak

28
Q

What are the signs of TGE in growing, finishing, and adult swine?

A

Inappetence, diarrhea, or unnoticed

29
Q

What happens to sows infected with TGE late in pregnancy?

A

They may develop fever, but rarely abort

30
Q

How can you diagnose TGE?

A

Sudden death in piglets, accompanies by vomiting and diarrhea
Immunofluorescence
Virus isolation
Rising antibody titers in paired sera from sows with affected litters or from pigs that have recovered from the disease
Electron microscopy- negative stain

31
Q

When should you vaccinate sows for TGE?

A

Vaccinate with an attenuated vaccine 3 weeks before farrowing in order to provide piglets with high levels of protective Ab in the colostrum

32
Q

What ages does feline infectious peritonitis (FIPV) affect?

A

Cats of all ages

33
Q

How many cats have antibodies against FIPV?

A

Over 90%

34
Q

What does FIPV occur in association with?

A

Retroviruses (parvovirus)

35
Q

What may be a variant of FIPV?

A

Feline coronavirus that causes diarrhea

36
Q

What are the clinical signs of FIP?

A 
Depressed and may have a fever
Classic wet form abdominal distention
Peritonitis
Pleuritis results in dyspnea
Neurologic and ocular disease
37
Q

What are the methods of diagnosis for FIP?

A

Virus isolation
Detection of antibody
Hypergammaglobulinemia

38
Q

How is FIP spread?

A

By aerosol

39
Q

Which cats develop a more rapidly progressive form of FIP, seropositive or seronegative?

A

Seropositive

40
Q

What does canine coronavirus cause?

A

A mild gasstroenteritis

41
Q

What does canine coronovirus occur in association with?

A

Canine parvovirus infection

42
Q

What does canine coronavirus commonly infect?

A

Pups

43
Q

What is canine coronavirus serologically closely related to?

A

TGE, but canine coronavirus does not infect pigs

44
Q

What are the methods of diagnosing canine coronavirus?

A

Virus isolation

EM

45
Q

What kind of vaccine is available for canine coronavirus?

A

Inactivated vaccine

46
Q

What did mouse hepatitis virus (MHV) serve as a model system for?

A

Coronavirus infection

47
Q

What does MHV cause?

A

Hepatitis
Encephalomyelitis
Enteritis
Nephritis

48
Q

What are the type and severity of MHV dependent on?

A

The strain of the virus and the age and strain of the mouse

49
Q

What happens to neonatal mice if there are brought into an environment infected with MHV?

A

They suffer high mortality

50
Q

What is porcine hemagglutinating encephalomyelitis virus (PHEV) in?

A

Primarily in piglets under 2 weeks of age

51
Q

What are the signs of PHEV?

A 
Anorexia
Hyperesthesia
Muscle tremors
Paddling of the legs
Vomiting
Often leading to emaciation and death
52
Q

Where is infection with PHEV?

A

The upper respiratory tract and pharynx and spread to the brain via peripheral nerves

53
Q

How is PHEV clinically diagnosed?

A

Virus isolation in primary cultures of porcine cells and detecting the virus by HA

54
Q

What does bovine coronavirus primarily affect?

A

The villi of the small intestine

It also affects glucose and lactose metabolism

55
Q

Which has a more severe villous atrophy, rotavirus or bovine coronavirus?

A

Bovine coronavirus

56
Q

What does bovine coronavirus destroy?

A

The absorptive cells in the intestine

57
Q

What is infectious bronchitis virus caused by?

A

Coronavirus

58
Q

What are the clinical manifestations infectious bronchitis virus?

A

Respiratory associated:

  • Wet eyes
  • Gasping
  • Coughing and sneezing
  • Tracheal rales
  • Nasal discharge

Nonrespiratory associated:

  • Decreased egg production
  • Misshapen eggs
  • Nephritis/nephrosis
59
Q

What is the importance of infectious bronchitis virus to the poultry industry?

A 
Increased mortality
Decreased production
Increased condemnation at processing
Increased downgrading of carcasses
Slowing of the line speed during the inspection process
60
Q

What is the method of prevention for infectious bronchitis virus?

A

Biosecurity

61
Q

What does bluecomb disease affect?

A

Turkeys of all ages, but is most severe in 1 to 6 week old poults

62
Q

What is bluecomb disease characterized by?

A 
Loss of appetite
Chirping
Diarrhea
Loss of weight
Skin of the head and neck may become cyanosed
Enteritis
63
Q

What causes porcine epidemic?

A

Porcine coronavirus

64
Q

What does porcine epidemic cause?

A

Acute diarrhea in swine of all ages

65
Q

What is the mortality rate in piglets with porcine epidemic?

A

50% or higher

66
Q

What is the specificity of coronavirus?

A

Host-specific

Infectious Agents II (25 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions